Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 188 time(s) and present in 94 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Mexico City West0.059733See
MEXMexico Mexico City East0.037579See
MEXMexico Veracruz, Poza Rica0.033345See
MEXMexico Mexico City Mestizo pop 20.0321234See
MEXMexico Mixtec0.031097See
MEXMexico Oaxaca Jamiltepec Mixtec0.031096See
MEXMexico Hidalgo Rural0.030981See
MEXMexico Tlaxcala, Tlaxcala city0.0276181See
MEXMexico Mestizo4.90.024041See
MEXMexico Mexico City Mestizo population0.0210143See
MEXMexico Mexico City Metropolitan Area Rural0.0197150See
MEXMexico Guadalajara Mestizo pop 20.0190103See
MEXMexico Tlaxcala Rural0.0169830See
MEXMexico San Luis Potosi, San Luis Potosi city0.016730See
MEXMexico Coahuila Rural0.0161216See
MEXMexico Nayarit Rural0.015664See
MEXMexico Nayarit, Tepic0.015597See
MEXMexico Jalisco, Tonala0.014335See
MEXMexico Sinaloa Rural0.0137183See
MEXMexico Zacatecas Rural0.0130266See
NICNicaragua Mestizo (G)2.60.0130155See
MEXMexico Jalisco, Guadalajara city0.01261189See
ARGArgentina Rosario Toba2.30.012086See
CUBCuba Mixed Race2.40.012042See
MEXMexico Tamaulipas Rural0.0119125See
USAUSA NMDP Mexican or Chicano0.0106261235See
MEXMexico Guerrero state0.0104144See
CHNChina North Han0.0100105See
CHNChina Guangdong Province Meizhou Han0.0100100See
MEXMexico Coahuila, Torreon0.0100396See
MEXMexico Baja Californa, Mexicali0.0100100See
MEXMexico Mexico City South0.009652See
MEXMexico Guanajuato Rural0.0092162See
MEXMexico Puebla Rural0.0090833See
MEXMexico Veracruz, Cordoba0.008956See
MEXMexico Nuevo Leon, Monterrey city0.0089226See
MEXMexico Michoacan Rural0.0086348See
CPVCape Verde Northwestern Islands0.008062See
MEXMexico Mexico City North0.0080751See
USAUSA South Texas Hispanic0.0080194See
USAUSA Hispanic pop 20.00781999See
MEXMexico Jalisco Rural0.0077585See
USAUSA Mexican American Mestizo0.0070553See
USAUSA Spain Ancestry0.0070279See
MEXMexico Oaxaca, Oaxaca city0.0066151See
MEXMexico Michoacan, Morelia0.0066150See
MEXMexico Durango, Durango city0.0065153See
USAUSA San Antonio Caucasian0.0060222See
MEXMexico Puebla, Puebla city0.00601994See
MEXMexico San Luis Potosi Rural0.005787See
MEXMexico Aguascalientes state0.005395See
MEXMexico Veracruz, Xalapa0.0053187See
CRICosta Rica Central Valley Mestizo (G)1.00.0050221See
MEXMexico Chihuahua, Ciudad Juarez0.0046106See
NICNicaragua Managua0.90.0045339See
USAUSA NMDP Hispanic South or Central American0.0043146714See
MEXMexico Chihuahua Chihuahua City0.0042119See
MEXMexico Chihuahua Rural0.0042236See
RUSRussia Bashkortostan, Bashkirs0.80.0042120See
MEXMexico Chiapas Rural0.0041121See
USAUSA Hispanic0.0040234See
CHNChina Beijing pop 20.0037826See
MEXMexico Tabasco Rural0.0035142See
MEXMexico Mexico City Center0.0032152See
MEXMexico Oaxaca Rural0.0031485See
MEXMexico Jalisco, Zapopan0.0030168See
USAUSA North American Native0.0030187See
USAUSA Asian0.0030358See
MEXMexico Veracruz, Veracruz city0.0029171See
CHESwitzerland Geneva pop 20.00251267See
BRABrazil Barra Mansa Rio State Caucasian0.0025405See
USAUSA San Diego0.30.0020496See
USAUSA African American0.0020252See
MEXMexico Veracruz Rural0.0018539See
MEXMexico Durango Rural0.0015326See
HKGHong Kong Chinese0.20.0010569See
USAUSA NMDP Caribean Hispanic0.0008115374See
USAUSA NMDP Hawaiian or other Pacific Islander0.000211499See
USAUSA Arizona Gila River Pima0.00023000See
ISRIsrael Argentina Jews0.00014307See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
USAUSA NMDP Korean0.000177584See
USAUSA NMDP Japanese0.000124582See
USAUSA NMDP African0.000128557See
USAUSA NMDP North American Amerindian0.000135791See
ISRIsrael USA Jews0.00016058See
ISRIsrael Georgia Jews0.00004471See
USAUSA NMDP Caribean Black0.000033328See
USAUSA NMDP Filipino0.000050614See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP European Caucasian0.00001242890See
ISRIsrael Iran Jews0.00008153See
USAUSA NMDP South Asian Indian0.0000185391See
DEUGermany DKMS - German donors0.00003456066See
DEUGermany pop 80.000039689See
GNBGuinea Bissau0.000065See
NIRIreland Northern0.00.00001000See
ITAItaly Bergamo0.00.0000101See
KORSouth Korea pop 30.0000485See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Rimaibe0.000047See
CPVCape Verde Southeastern Islands0.000062See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina Inner Mongolia Region0.0000102See
CHNChina Qinghai Province Hui0.0000110See
CHNChina Tibet Region Tibetan0.0000158See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
ECUEcuador Coast Mixed Ancestry0.0000238See
ECUEcuador Amazonia Mixed Ancestry0.000039See
ECUEcuador Andes Mixed Ancestry0.0000824See
ECUEcuador Mixed Ancestry0.00001173See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Morelos Rural0.000030See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
MEXMexico Coahuila, Saltillo0.000072See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
PHLPhilippines Ivatan0.00.000050See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
NLDNetherlands Leiden0.00001305See
USAUSA African American pop 40.00002411See
USAUSA Asian pop 20.00001772See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Caucasian pop 20.0000265See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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