Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 106 time(s) and present in 67 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MYSMalaysia Kedah Baling Kensiu0.060025See
MYSMalaysia Kelantan7.10.054028See
IDNIndonesia Java pop 20.042036See
MYSMalaysia Patani8.00.040025See
SGPSingapore Thai0.0400100See
MYSMalaysia Mandailing7.40.037027See
THAThailand pop 30.031049See
IDNIndonesia Java Western5.90.0300236See
IDNIndonesia Sundanese and Javanese0.0270201See
MYSMalaysia Peninsular Malay4.60.0242951See
MYSMalaysia Kedah Kensiu4.80.024021See
SGPSingapore SGVP Malay MAS0.024089See
USAUSA NMDP Filipino0.023650614See
MYSMalaysia Jelebu Temuan0.021025See
VNMVietnam Kinh4.00.0198101See
MYSMalaysia Champa3.50.017029See
USAUSA NMDP Vietnamese0.010843540See
TWNTaiwan Minnan pop 12.00.0100102See
SGPSingapore Javaneses0.010051See
SGPSingapore Riau Malay0.0100132See
VNMVietnam Hanoi Kinh pop 20.0090170See
PNGPapua New Guinea Wanigela Keapara0.008066See
CHNChina Yunnan Province Lisu0.0070111See
USAUSA Asian0.0070358See
MYSMalaysia Peninsular Chinese1.00.0052194See
CHNChina Guangxi Region Maonan0.0050108See
USAUSA NMDP Southeast Asian0.004127978See
CHNChina Southwest Dai0.0040124See
CHNChina Yunnan Bulang0.0040116See
MYSMalaysia Peninsular Indian0.70.0037271See
USAUSA NMDP Hawaiian or other Pacific Islander0.003411499See
USAUSA North American Native0.0030187See
SGPSingapore Chinese0.70.0030149See
USAUSA Asian pop 20.00281772See
USAUSA San Diego0.30.0020496See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.30.00145266See
HKGHong Kong Chinese BMDR0.00127595See
HKGHong Kong Chinese cord blood registry0.00103892See
CHNChina Jiangsu Han0.00103238See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
TWNTaiwan Han Chinese0.0010504See
HKGHong Kong Chinese0.20.0010569See
USAUSA African American pop 30.0010564See
USAUSA NMDP Chinese0.001099672See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000946682See
DEUGermany DKMS - China minority0.00081282See
CHNChina Zhejiang Han0.00061734See
CHNChina Hubei Han0.10.00053732See
DEUGermany DKMS - France minority0.00041406See
USAUSA African American pop 40.00042411See
SAUSaudi Arabia pop 6 (G)0.000328927See
DEUGermany DKMS - Netherlands minority0.00041374See
USAUSA NMDP African American pop 20.0003416581See
DEUGermany DKMS - Turkey minority0.00024856See
USAUSA NMDP Mexican or Chicano0.0001261235See
USAUSA NMDP African0.000128557See
JPNJapan pop 160.000118604See
USAUSA NMDP South Asian Indian0.0001185391See
USAUSA NMDP Hispanic South or Central American0.0001146714See
USAUSA NMDP Korean0.000177584See
USAUSA NMDP Japanese0.000124582See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000070890See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP Caribean Hispanic0.0000115374See
USAUSA NMDP North American Amerindian0.000035791See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA Hispanic pop 20.00001999See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
ZAFSouth Africa Natal Zulu0.00.0000100See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
DEUGermany pop 80.000039689See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
USAUSA Hispanic0.0000234See
SGPSingapore SGVP Chinese CHS0.000096See
SGPSingapore SGVP. Indian INS0.000086See
NCLNew Caledonia0.000065See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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