Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 93 time(s) and present in 53 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHLChile Mapuche0.061566See
ARGArgentina Gran Chaco Mataco Wichi10.90.054049See
ARGArgentina Gran Chaco Western Toba Pilaga7.10.036019See
BRABrazil Terena5.20.034060See
PERPeru Titikaka Lake Uro0.0140105See
PERPeru Titikaka Lake Uros0.0140105See
BRABrazil Belo Horizonte Caucasian2.10.011095See
PRTPortugal South0.010049See
COLColombia North Wiwa El Encanto0.009652See
ARGArgentina Gran Chaco Eastern Toba1.70.0090135See
PRTPortugal Azores Terceira Island1.80.0088130See
PRTAzores Terceira Island0.0080130See
USAUSA South Texas Hispanic0.0080194See
USAUSA Hispanic0.0060234See
CZECzech Republic0.0050106See
USAUSA NMDP Hispanic South or Central American0.0043146714See
COLColombia Bogotá Cord Blood0.80.00411463See
USAUSA Caucasian pop 20.0040265See
MYSMalaysia Peninsular Indian0.70.0037271See
CHESwitzerland Basel0.00361888See
USAUSA NMDP Caribean Hispanic0.0033115374See
USAUSA NMDP Caribean Indian0.003014339See
USAUSA San Antonio Caucasian0.0030222See
NIRIreland Northern0.40.00201000See
USAUSA Caucasian pop 40.00191070See
NICNicaragua Managua0.30.0015339See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
USAUSA European American pop 20.00101245See
USAUSA NMDP American Indian South or Central America0.00105926See
USAUSA NMDP Mexican or Chicano0.0007261235See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00064335See
USAUSA Hispanic pop 20.00051999See
DEUGermany DKMS - Netherlands minority0.00041374See
ISRIsrael USA Jews0.00026058See
USAUSA NMDP Caribean Black0.000233328See
JPNJapan pop 160.000118604See
USAUSA NMDP North American Amerindian0.000135791See
USAUSA NMDP Hawaiian or other Pacific Islander0.000011499See
ISRIsrael Poland Jews0.000013871See
USAUSA NMDP Japanese0.000024582See
USAUSA NMDP African American pop 20.0000416581See
USAUSA NMDP African0.000028557See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000070890See
ISRIsrael Morocco Jews0.000036718See
USAUSA NMDP Korean0.000077584See
ISRIsrael YemenJews0.000015542See
ISRIsrael USSR Jews0.000045681See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA African American0.0000252See
USAUSA Alaska Yupik0.0000252See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
NLDNetherlands Leiden0.00001305See
POLPoland DKMS0.000020653See
PRTPortugal North0.000046See
PRTPortugal Center0.000050See
SGPSingapore Chinese0.00.0000149See
CHNChina Tibet Region Tibetan0.0000158See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
HKGHong Kong Chinese0.00.0000569See
ITAItaly North pop 30.00.000097See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHNChina North Han0.0000105See
USAUSA North American Native0.0000187See
USAUSA Asian0.0000358See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA African American pop 80.0000605See
USAUSA African American pop 40.00002411See
USAUSA Asian pop 20.00001772See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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