Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 82 time(s) and present in 49 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
COLColombia Arhuaco NA-DHS_16 (G)70.60.441217See
COLColombia Kogi NA-DHS_17 (G)71.40.428615See
COLColombia North Wiwa El Encanto0.384652See
CRICosta Rica Guaymi NA-DHS_10 (G)55.60.277818See
CRICosta Rica Cabecar NA-DHS_9 (G)36.80.210519See
COLColombia Zenu NA-DHS_18 (G)37.50.187516See
VENVenezuela Perja Mountain Bari0.159055See
COLColombia North Chimila Amerindians0.138247See
COLColombia Inga NA-DHS_11 (G)21.40.107116See
COLColombia Bogotá Cord Blood16.50.08651463See
COLColombia Wayuu NA-DHS_15 (G)13.30.066715See
GTMGuatemala Kaqchikel NA-DHS_8 (G)10.50.052619See
NICNicaragua Managua9.00.0482339See
MEXMexico Zapotec NA-DHS_7 (G)5.90.029420See
MEXMexico Oaxaca Jamiltepec Mixtec0.021096See
MEXMexico Mixtec0.021097See
MEXMexico Mexico City Mestizo pop 20.0192234See
USAUSA NMDP Hispanic South or Central American0.0185146714See
MEXMexico Tixcacaltuyub Maya0.014967See
MEXMexico Chiapas Lacandon Mayans0.0115218See
USAUSA Spain Ancestry0.0110279See
MEXMexico Mexico City Mestizo population0.0105143See
MEXMexico Guadalajara Mestizo pop 20.0100103See
MEXMexico Oaxaca Mixe0.009055See
USAUSA Hispanic pop 20.00801999See
ESPSpain, Canary Islands, Gran canaria island0.90.0047215See
USAUSA NMDP Mexican or Chicano0.0047261235See
USAUSA Mexican American Mestizo0.0040553See
USAUSA NMDP American Indian South or Central America0.00405926See
CHNChina Tibet Region Tibetan0.0030158See
USAUSA NMDP Caribean Hispanic0.0019115374See
USAUSA NMDP Caribean Indian0.001014339See
USAUSA African American pop 30.0010564See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00054335See
USAUSA African American pop 40.00042411See
DEUGermany DKMS - Spain minority0.00051107See
USAUSA NMDP Caribean Black0.000433328See
USAUSA NMDP Hawaiian or other Pacific Islander0.000311499See
USAUSA NMDP North American Amerindian0.000235791See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
ISRIsrael Argentina Jews0.00014307See
USAUSA NMDP African American pop 20.0001416581See
USAUSA NMDP Filipino0.000150614See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP Southeast Asian0.000027978See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Chinese0.000099672See
NLDNetherlands Leiden0.00001305See
DEUGermany pop 80.000039689See
USAUSA Asian pop 20.00001772See
MARMorocco Settat Chaouya0.00.000098See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
CHNChina North Han0.0000105See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
MEXMexico Mestizo0.00.000041See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
NIRIreland Northern0.00.00001000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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