Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 283 time(s) and present in 131 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Yunnan Province Han pop 20.1790129See
TWNTaiwan Chinese immigrants from South China0.1720172See
TWNTaiwan Hakka pop 20.1560714See
TWNTaiwan Chinese immigrants from Middle China0.1500211See
TWNTaiwan Minnan pop 20.14607137See
TWNTaiwan Minnan and Hakka0.1360190See
CHNChina Wuhan26.70.1350121See
THAThailand pop 40.132016807See
CHNChina Guangdong Province24.60.1316403See
CHNChina Shanghai0.112026266See
VNMVietnam Hanoi0.110050See
CHNChina Jiangsu Province0.094020248See
TWNTaiwan Chinese immigrants from North China0.0860152See
CHNChina Shaanxi Province Han0.079010000See
JPNJapan Aichi15.20.076050See
MMRMyanmar Shan13.00.064854See
JPNJapan Kyoto and Osaka0.0640165See
USAUSA OPTN Asian0.0620261See
CHNChina Yunnan Province Naxi0.0610118See
CHNChina Shandong Province10.90.05607418See
BRABrazil Parana Japanese10.00.0521192See
JPNJapan Hyogo Osaka and Nagano0.0510195See
KORSouth Korea pop 80.04907096See
JPNJapan Hyogo9.40.047032See
MMRMyanmar Mon9.40.046964See
KORSouth Korea pop 10.0460324See
MMRMyanmar Bamar8.70.043547See
JPNJapan pop 20.0410916See
CHNChina Harbin Manchu0.0410172See
JPNJapan Tohoku Region0.0390322See
JPNJapan pop 116.50.033062See
CHNChina Shandong Province Linqu County6.50.0330139See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks5.40.0270112See
MYSMalaysia pop 20.026062See
MYSMalaysia Sabah Kadazan0.026057See
RUSRussia South Ural Bashkir4.80.0240146See
MYSMalaysia Perak Rawa0.020023See
MYSMalaysia pop 30.01901445See
RUSRussia Sakhalin Island Nivkhi0.019053See
MNGMongolia Oold0.0190104See
CHNChina Harbin Korean0.0170201See
MEXMexico Jalisco, Tonala0.014335See
MKDMacedonia MBMDR - Macedonian Muslims2.60.013276See
MEXMexico Hidalgo, Pachuca0.012241See
MNGMongolia Ulaanbaatar Khalkha0.012041See
RUSRussia South Ural Tatar2.20.0110135See
MYSMalaysia Negeri Sembilan Minangkabau0.010034See
MEXMexico Mexico City South0.009652See
MMRMyanmar Kayah1.80.009155See
TWNTaiwan Aborigine0.0090111See
BRABrazil Curitiba-Parana Mixed0.0082264See
MMRMyanmar Kachin1.60.007963See
RUSRussia Transbaikal Territory Buryats1.00.0070150See
ARMArmenia Shirak0.007076See
RUSRussia Tatars0.0056355See
MNGMongolia Khalkha pop 20.0050202See
MNGMongolia Khalkha0.0050200See
PAKPakistan Brahui0.0050104See
RUSRussia Northwest pop 31.00.0050100See
BRABrazil Belem Mixed1.00.0050100See
BIHBosnia and Herzegovina pop 20.80.0042120See
TURTurkey pop 50.0040142See
GRCGreece pop30.80.0040246See
MEXMexico Mexico City Metropolitan Area Rural0.0033150See
MEXMexico Mexico City Center0.0032152See
PERPeru Arequipa Mestizo0.70.0030168See
RUSRussia Samara Region0.00302500See
SAUSaudi Arabia pop 20.0030383See
BGDBangladesh Dhaka Bangalee0.0030141See
INDIndia North Gujarat0.60.0030338See
ITAItaly pop 60.50.0027184See
FRAFrance Marseille0.50.00261000See
SWESweden pop 40.30.0021966See
GBRUnited Kingdom renal patients0.30.00207007See
RUSRussia Moscow0.00202650See
IRNIran Royan Cord Blood Bank0.40.002015600See
BRABrazil Parana Cafuzo0.30.0020319See
RUSRussia Moscow Pop 20.40.00182000See
MEXMexico Jalisco Rural0.0017585See
MEXMexico Puebla, Puebla city0.00101994See
BRABrazil South East Cord Blood0.001011409See
MEXMexico Oaxaca Rural0.0010485See
AUSAustralia West Caucasian0.10.0010891See
WALWales pop 20.10.001039979See
BRABrazil Rio Grande do Norte Mestizo0.001012973See
FRAFrance Bordeaux0.20.0010990See
USAUSA OPTN Hispanic0.00101580See
PRTPortugal Portalegre0.00101254See
BRABrazil REDOME Parana0.0008341639See
BRABrazil REDOME Sao Paulo0.0007800809See
NORNorway ethnic Norwegians0.10.00064510See
MEXMexico Tlaxcala Rural0.0006830See
IRNIran pop 40.0006855See
BRABrazil REDOME Mato Grosso do Sul0.000595667See
FRAFrance Rennes pop 40.10.00051000See
FRAFrance Lyon0.10.00054813See
BRABrazil REDOME Alagoas0.000425349See
BRABrazil REDOME Sergipe0.00047321See
MKDMacedonia MBMDR - Macedonian0.10.00041283See
BRABrazil REDOME Tocantins0.000320692See
BRABrazil REDOME Rio Grande do Norte0.000346603See
BRABrazil REDOME Federal District0.000329549See
BRABrazil REDOME Maranhao0.000310180See
BRABrazil REDOME Mato Grosso0.000334649See
ROMRomania pop 30.10.00031469See
SRBSerbia pop 30.10.00031992See
SVKSlovakia pop 20.00034234See
POLPoland pop 30.00.00022907See
BRABrazil REDOME Bahia0.000247399See
BRABrazil REDOME Minas Gerais0.0002211275See
BRABrazil REDOME Para0.000272637See
BRABrazil REDOME Paraiba0.000243868See
BRABrazil REDOME Pernambuco0.000292332See
BRABrazil REDOME Rio de Janeiro0.0002139322See
BRABrazil REDOME Roraima0.00024140See
BRABrazil REDOME Rondonia0.000254396See
BRABrazil REDOME Santa Catarina0.0002106673See
BRABrazil REDOME Goias0.000288574See
BRABrazil REDOME Rio Grande do Sul0.0001241329See
BRABrazil REDOME Piaui0.000146140See
BRABrazil Rio Grande do Sul Caucasoid0.00014428See
BRABrazil REDOME Espirito Santo0.000188485See
BRABrazil REDOME Ceara0.0001101217See
BRABrazil REDOME Amazonas0.000124129See
BRABrazil REDOME Amapa0.000117864See
GRCGreece pop 70.000111250See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
PRTPortugal North0.000046See
ARGArgentina La Plata0.00.0000100See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
ESPSpain Majorca0.0000407See
ESPSpain Minorca0.000094See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ESPSpain Murcia0.0000173See
ZAFSouth Africa Natal Zulu0.00.0000100See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
BRABrazil Sao Paulo Mixed0.00.0000239See
GRCGreece North0.0000500See
MNGMongolia Tsaatan0.0000144See
FRAFrance Southeast0.00.0000130See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
MKDMacedonia pop 40.0000216See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Baloch0.000066See
ARGArgentina Cuyo Region0.00.0000420See
USAUSA OPTN African American0.00001510See
BRABrazil Parana Mulatto0.00.0000186See
BRABrazil Parana Afro Brazilian0.00.000077See
BRABrazil Parana Oriental0.00.000033See
CHNChina North Han0.0000105See
PRTPortugal South pop 20.00001021See
PAKPakistan Karachi Parsi0.000091See
ENGEngland Leeds0.00.00005024See
HRVCroatia pop 20.0000100See
ARGArgentina Buenos Aires pop 20.10.00001216See
MNGMongolia Tarialan Khoton0.000085See
ITAItaly South Campania Region0.00.00001089See
BRABrazil Parana Caucasian0.00.00002775See
IRLIreland South pop 20.000017624See
ARGArgentina Corrientes0.00.0000155See
BRABrazil Piaui Mixed0.000021943See
MARMorocco pop 20.0000110See
MEXMexico Mexico City Mestizo0.0000121See
MEXMexico Puebla Mestizo0.000099See
MEXMexico Sinaloa Mestizo0.000056See
RUSRussia Northwest pop 20.00.0000346See
RUSRussia South Ural Russian0.00.0000207See
AREUnited Arab Emirates pop 20.00.0000373See
PRTPortugal Porto0.00007937See
PRTPortugal Santarem0.00003865See
PRTPortugal Setubal0.00005268See
PRTPortugal Viana do Castelo0.0000706See
PRTPortugal Vila Real0.00001167See
PRTPortugal Viseu0.00002915See
PRTMadeira pop 30.0000538See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.000094See
TZATanzania Dodoma Kongwa0.0000212See
BIHBosnia and Herzegovina0.0000134See
USAUSA OPTN Caucasian0.00008525See
PRTPortugal Aveiro0.00005933See
PRTPortugal Beja0.0000699See
PRTPortugal Braga0.00001971See
PRTPortugal Bragança0.0000301See
PRTPortugal Castelo Branco0.0000327See
PRTPortugal Coimbra0.00005057See
PRTPortugal Evora0.0000737See
PRTPortugal Faro0.00001242See
PRTPortugal Guarda0.0000797See
PRTPortugal Leiria0.00001847See
PRTPortugal Lisbon0.000017420See
BRABrazil Sao Paulo Bauru Mixed0.00003542See
GBRUnited Kingdom South West0.0000163See
ECUEcuador Coast Mixed Ancestry0.0000238See
ECUEcuador Amazonia Mixed Ancestry0.000039See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Guerrero state0.0000144See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Jalisco, Guadalajara city0.00001189See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Coahuila, Torreon0.0000396See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Durango Rural0.0000326See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Zacatecas Rural0.0000266See
MEXMexico Nayarit Rural0.000064See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
ECUEcuador Andes Mixed Ancestry0.0000824See
ECUEcuador Mixed Ancestry0.00001173See
MEXMexico Michoacan Rural0.0000348See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Veracruz Rural0.0000539See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Puebla Rural0.0000833See
MEXMexico Mexico City North0.0000751See
MEXMexico Mexico City East0.000079See
MEXMexico Morelos Rural0.000030See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional