Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 233 time(s) and present in 92 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CMRCameroon Ewondo0.040038See
ZAFSouth Africa Tswana7.30.037041See
TZATanzania Dodoma Kongwa0.0330212See
USAUSA OPTN African American0.02401510See
MEXMexico Tabasco, Villahermosa0.018382See
BRABrazil Rio Grande do Sul Black0.0180248See
CMRCameroon Bamileke 20.014035See
BRABrazil Parana Afro Brazilian2.60.013077See
AREUnited Arab Emirates pop 22.10.0110373See
BRABrazil South Ribeirao Preto0.0110184See
USAUSA African American Bethesda2.10.0110187See
BRABrazil REDOME Bahia0.007947399See
BRABrazil REDOME Sergipe0.00797321See
BRABrazil REDOME Piaui0.007646140See
BRABrazil Para Cord Blood Unit0.00.0071841See
BRABrazil REDOME Roraima0.00704140See
BRABrazil REDOME Paraiba0.007043868See
BRABrazil Piaui Mixed0.007021943See
MEXMexico Tapachula, Chiapas Mestizo Population1.40.007072See
BRABrazil REDOME Rio de Janeiro0.0068139322See
BRABrazil REDOME Pernambuco0.006492332See
BRABrazil REDOME Acre0.0064859See
BRABrazil REDOME Maranhao0.006210180See
BRABrazil REDOME Tocantins0.006120692See
BRABrazil South East Cord Blood0.006011409See
BRABrazil Parana Cafuzo1.20.0060319See
BOLBolivia La Paz Aymaras0.006087See
BRABrazil REDOME Alagoas0.006025349See
BRABrazil REDOME Espirito Santo0.005988485See
MEXMexico Veracruz, Veracruz city0.0058171See
COLColombia Barranquilla0.0055188See
BRABrazil REDOME Rio Grande do Norte0.005546603See
MEXMexico Sonora Rural0.0051197See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.005094See
BRABrazil Parana Mixed race1.10.0050186See
BRABrazil Minas Gerais State Mixed0.90.00501000See
BRABrazil Belem Mixed1.00.0050100See
BRABrazil Rio Grande do Norte Mestizo0.005012973See
BRABrazil REDOME Ceara0.0050101217See
MEXMexico Puebla Mestizo0.005099See
MEXMexico Baja Californa, Mexicali0.0050100See
MEXMexico Zacatecas, Fresnillo0.0048103See
BRABrazil REDOME Rondonia0.004754396See
BRABrazil Para State0.00.00465000See
BRABrazil REDOME Mato Grosso0.004534649See
BRABrazil REDOME Mato Grosso do Sul0.004595667See
BRABrazil REDOME Minas Gerais0.0045211275See
ECUEcuador Coast Mixed Ancestry0.0042238See
BRABrazil REDOME Federal District0.004229549See
BRABrazil REDOME Goias0.004288574See
BRABrazil REDOME Sao Paulo0.0041800809See
BRABrazil REDOME Para0.003972637See
BRABrazil REDOME Amazonas0.003824129See
BRABrazil REDOME Amapa0.003517864See
MEXMexico Tabasco Rural0.0035142See
BRABrazil Rio Grande do Sul Mixed0.0030324See
BGDBangladesh Dhaka Bangalee0.0030141See
ARGArgentina Corrientes0.60.0030155See
SAUSaudi Arabia pop 40.60.0030499See
BRABrazil REDOME Parana0.0028341639See
MEXMexico Veracruz Rural0.0028539See
MEXMexico Yucatan, Merida0.0026192See
BRABrazil Parana Japanese1.00.0026192See
MEXMexico Coahuila, Torreon0.0025396See
KURIraq Kurdistan Region0.50.0020209See
BRABrazil Sao Paulo Bauru Mixed0.00203542See
CHNChina Shandong Province0.30.00207418See
BRABrazil REDOME Rio Grande do Sul0.0019241329See
MEXMexico Zacatecas Rural0.0019266See
MEXMexico Jalisco, Guadalajara city0.00171189See
BRABrazil Paraná Caucasian0.30.0016641See
BRABrazil REDOME Santa Catarina0.0014106673See
ECUEcuador Mixed Ancestry0.00131173See
BRABrazil Rio Grande do Sul Caucasoid0.00114428See
BRABrazil Parana Caucasian0.20.00102775See
ARGArgentina Buenos Aires0.20.0010466See
CHNChina Shaanxi Province Han0.001010000See
IRNIran Royan Cord Blood Bank0.30.001015600See
CHNChina Jiangsu Province0.001020248See
SAUSaudi Arabia pop 20.0010383See
THAThailand pop 40.001016807See
USAUSA OPTN Hispanic0.00101580See
WALWales pop 20.00.001039979See
ECUEcuador Andes Mixed Ancestry0.0006824See
CHNChina Shanghai0.000626266See
CHLChile Santiago0.0005920See
MEXMexico Puebla, Puebla city0.00051994See
IRLIreland South pop 20.000117624See
ISRIsrael Jews pop 20.00.000123000See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
ITAItaly South Campania Region0.00.00001089See
ITAItaly North Pavia pop 20.00.00002416See
MARMorocco pop 20.0000110See
MEXMexico Mexico City Mestizo0.0000121See
ESPSpain Majorca0.0000407See
ESPSpain Minorca0.000094See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ESPSpain Murcia0.0000173See
ESPSpain, Castilla y Leon, Northwest,0.00.00001743See
FRAFrance Grenoble, Nantes and Rennes0.00006094See
GRCGreece North0.0000500See
HRVCroatia pop 20.0000100See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Sinaloa Mestizo0.000056See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Puebla Rural0.0000833See
MEXMexico Oaxaca Rural0.0000485See
MEXMexico Morelos Rural0.000030See
MEXMexico Baja California Rural0.000050See
MEXMexico Nayarit Rural0.000064See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Tlaxcala Rural0.0000830See
MEXMexico Jalisco Rural0.0000585See
MEXMexico Michoacan Rural0.0000348See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Durango Rural0.0000326See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Xalapa0.0000187See
CHNChina North Han0.0000105See
ECUEcuador Amazonia Mixed Ancestry0.000039See
CMRCameroon Uldeme0.000035See
CMRCameroon Podokwo0.000043See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
ARGArgentina Buenos Aires pop 20.00.00001216See
ARGArgentina Cuyo Region0.00.0000420See
AUSAustralia West Caucasian0.00.0000891See
ARGArgentina La Plata0.00.0000100See
BIHBosnia and Herzegovina0.0000134See
BRABrazil Sao Paulo Mixed0.00.0000239See
BRABrazil Parana Oriental0.00.000033See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
MYSMalaysia Perak Rawa0.000023See
MEXMexico Nayarit, Tepic0.000097See
MYSMalaysia pop 20.000062See
USAUSA OPTN Caucasian0.00008525See
USAUSA OPTN Asian0.0000261See
USAUSA South Texas Hispanic0.0000194See
USAUSA Caucasian Bethesda0.00.0000307See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
RUSRussia South Ural Russian0.00.0000207See
RUSRussia South Ural Bashkir0.00.0000146See
RUSRussia South Ural Tatar0.00.0000135See
RUSRussia Northwest pop 30.00.0000100See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Guerrero state0.0000144See
MKDMacedonia pop 40.0000216See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Mexico City North0.0000751See
MEXMexico Mexico City East0.000079See
MEXMexico Mexico City Center0.0000152See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
PRTPortugal North0.000046See
PRTPortugal South pop 20.00001021See
PRTPortugal Aveiro0.00005933See
PRTPortugal Beja0.0000699See
PRTPortugal Braga0.00001971See
PRTPortugal Bragança0.0000301See
PRTPortugal Vila Real0.00001167See
PRTPortugal Viseu0.00002915See
PRTMadeira pop 30.0000538See
PRTPortugal Lisbon0.000017420See
PRTPortugal Portalegre0.00001254See
PRTPortugal Porto0.00007937See
PRTPortugal Santarem0.00003865See
PRTPortugal Setubal0.00005268See
PRTPortugal Viana do Castelo0.0000706See
PRTPortugal Castelo Branco0.0000327See
PRTPortugal Coimbra0.00005057See
PRTPortugal Evora0.0000737See
PRTPortugal Faro0.00001242See
PRTPortugal Guarda0.0000797See
PRTPortugal Leiria0.00001847See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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