Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 35 time(s) and present in 26 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ZAFSouth African Black17.70.0916142See
USAUSA African American pop 30.0740564See
CPVCape Verde Northwestern Islands0.073062See
USAUSA Spain Ancestry0.0610279See
CRICosta Rica African -Caribbean (G)11.80.0590102See
BRABrazil Barra Mansa Rio State Black0.034273See
CPVCape Verde Southeastern Islands0.024062See
BRABrazil Rio de Janeiro Parda0.0237170See
BRABrazil Rio de Janeiro Black0.022168See
CRICosta Rica Guanacaste Mestizo (G)2.80.0140110See
BRABrazil Rio de Janeiro Caucasian0.0106521See
MARMorocco Settat Chaouya0.010098See
MARMorocco Atlantic Coast Chaouya0.010098See
USAUSA Mexican American Mestizo0.0080553See
BRABrazil Barra Mansa Rio State Caucasian0.0062405See
BRABrazil Mixed0.0050108See
LBYLibya Cyrenaica0.0040118See
INDIndia Kerala Malayalam speaking0.30.0030356See
NICNicaragua Mestizo (G)0.60.0030155See
USAUSA Italy Ancestry0.0020273See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
RUSRussia Nizhny Novgorod, Russians0.10.00031510See
POLPoland BMR0.00.000223595See
USAUSA Arizona Gila River Pima0.00023000See
USAUSA Caucasian0.00.000061655See
NIRIreland Northern0.00.00001000See
MKDMacedonia pop 10.0000158See
GNBGuinea Bissau0.000065See
KORSouth Korea pop 30.0000485See
MARMorocco Nador Metalsa0.000099See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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