Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 410 time(s) and present in 345 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
WSMSamoa West0.454022See
CHNChina Shanghai0.187026266See
RUSRussia Nenet Mixed0.182055See
PERPeru Arequipa Mestizo32.20.1760168See
CHNChina Han31.20.1705314See
JPNJapan pop 80.1700308See
TWNTaiwan Chinese immigrants from South China0.1640172See
CHNChina Jiangsu Province0.162020248See
CHNChina Wuhan30.60.1570121See
JPNJapan pop 100.1570332See
TWNTaiwan Hakka pop 20.1570714See
TWNTaiwan Chinese immigrants from Middle China0.1560211See
TWNTaiwan Minnan pop 20.15407137See
CHNChina Guangdong Province25.80.1386403See
TWNTaiwan Chinese immigrants from North China0.1360152See
CHNChina Shaanxi Province Han0.132010000See
CHNChina Beijing and Guangzhou0.13101592See
THAThailand pop 20.1250124See
CHNChina Shandong Province22.70.12107418See
ARGArgentina Kolla0.120061See
THAThailand pop 40.115016807See
RUSRussia Mari0.1140202See
BRABrazil Parana Oriental21.20.106033See
CANCanada British Columbia Athabaskan0.105062See
INDIndia Northeast Lachung0.103058See
USAUSA OPTN Asian0.1030261See
ECUEcuador Amazonia Mixed Ancestry0.102639See
KORSouth Korea pop 80.10207096See
VNMVietnam Hanoi0.100050See
CANCanada British Columbia Penutian0.096026See
MNGMongolia Khalkha0.0950200See
ECUEcuador Andes Mixed Ancestry0.0922824See
INDIndia Andhra Pradesh Sunni4.60.0900100See
MYSMalaysia Perak Rawa0.090023See
INDIndia Northeast Mech0.087063See
KORSouth Korea pop 10.0850324See
THAThailand Northeast0.084066See
ECUEcuador Mixed Ancestry0.08351173See
INDIndia Andhra Pradesh Brahmin3.90.077098See
MNGMongolia Oold0.0770104See
NORNorway Sami0.0730200See
THAThailand Northeast pop 20.0710400See
TURTurkey pop 20.0680228See
USAUSA Southeast African American12.50.0670112See
MMRMyanmar Shan13.00.064854See
CHNChina Shandong Province Linqu County12.20.0629139See
MMRMyanmar Rakhine12.50.062548See
TTOTrinidad African0.060067See
CODCongo Kinshasa Bantu11.10.056090See
ARGArgentina Salta Wichi pop 210.50.053019See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks8.90.0490112See
RUSRussia South Ural Bashkir9.60.0480146See
RUSRussia Murmansk Saomi Mixed0.043070See
ECUEcuador Coast Mixed Ancestry0.0420238See
TWNTaiwan Aborigine pop 20.042048See
BRABrazil Para Cord Blood Unit8.00.0416841See
PRTAzores Terceira Island0.0390130See
BRABrazil South Ribeirao Preto0.0380184See
INDIndia Northeast Rastogi0.0380196See
INDIndia Northeast Shia0.0370190See
MYSMalaysia pop 20.037062See
RUSRussia Tatars0.0366355See
MYSMalaysia pop 30.03601445See
MEXMexico Veracruz, Cordoba0.035756See
BRABrazil Curitiba-Parana Mixed0.0339264See
MEXMexico Veracruz, Poza Rica0.033345See
MEXMexico Jalisco, Tlajomulco0.033330See
CUBCuba Mixed pop 20.0320189See
RUSRussia Arkhangelsk Pomor0.032063See
TWNTaiwan Aborigine0.0320111See
MMRMyanmar Mon6.30.031364See
INDIndia Northeast Rajbanshi0.031098See
RUSRussia Arkhangelsk0.031081See
RUSRussia South Ural Tatar5.90.0300135See
MYSMalaysia Negeri Sembilan Minangkabau0.030034See
BRABrazil Rio Grande do Sul Black0.0300248See
BFABurkina Faso Mossi0.030053See
MEXMexico Campeche, Campeche city0.029434See
INDIndia Northeast Kayastha0.0280190See
BRABrazil Sao Paulo Mixed5.40.0280239See
MNGMongolia Tsaatan0.0280144See
BRABrazil REDOME Amapa0.027817864See
BRABrazil REDOME Amazonas0.027724129See
MEXMexico Coahuila Rural0.0275216See
BRABrazil REDOME Para0.027072637See
BRABrazil Guarani M bya0.027093See
BRABrazil Para State5.80.02705000See
USAUSA OPTN African American0.02701510See
BRABrazil REDOME Roraima0.02564140See
RUSRussia Vologda0.0250121See
MEXMexico Hidalgo, Pachuca0.024441See
TZATanzania Dodoma Kongwa0.0240212See
BRABrazil REDOME Maranhao0.023910180See
BRABrazil Piaui Mixed0.022021943See
BRABrazil REDOME Piaui0.022046140See
ARGArgentina Cuyo Region4.30.0220420See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
BRABrazil REDOME Tocantins0.021320692See
BRABrazil Rio Grande do Sul Mixed0.0210324See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.021096See
MEXMexico Tapachula, Chiapas Mestizo Population4.20.020872See
BRABrazil REDOME Mato Grosso do Sul0.020295667See
BRABrazil REDOME Bahia0.020247399See
BRABrazil Parana Cafuzo4.10.0200319See
BRABrazil Mato Grosso do Sul0.0200203See
ARGArgentina Buenos Aires pop 24.00.02001216See
BFABurkina Faso Rimaibe0.020047See
MEXMexico Quintana Roo Rural0.020050See
RUSRussia Northwest pop 34.00.0200100See
PHLPhilippines National Capital Region0.020051See
MEXMexico Oaxaca Rural0.0195485See
BRABrazil REDOME Goias0.019588574See
BRABrazil REDOME Pernambuco0.019492332See
MEXMexico Sinaloa Rural0.0191183See
MEXMexico Guadalajara Mestizo0.019054See
BRABrazil Parana Mixed race3.80.0190186See
BLRBelarus Brest Region0.0190105See
BRABrazil REDOME Alagoas0.018825349See
GBRUnited Kingdom Central0.0188135See
BRABrazil REDOME Paraiba0.018543868See
GBRUnited Kingdom Orkney0.018488See
MMRMyanmar Kayah3.60.018255See
MEXMexico Sinaloa Mestizo0.018056See
INDIndia Northeast Vaish0.0180198See
BRABrazil Minas Gerais State Mixed3.40.01801000See
BRABrazil REDOME Acre0.0180859See
ARGArgentina La Plata4.00.0180100See
SWESweden pop 50.01801569See
BRABrazil REDOME Rondonia0.017954396See
BRABrazil REDOME Mato Grosso0.017934649See
BRABrazil South East Cord Blood0.017311409See
BRABrazil REDOME Ceara0.0172101217See
ESPSpain Northwest Lugo3.40.0171145See
BRABrazil Rio Grande do Norte Mestizo0.017012973See
BRABrazil North East Mixed0.0170205See
BRABrazil REDOME Federal District0.016829549See
MEXMexico Chihuahua Chihuahua City0.0168119See
MEXMexico San Luis Potosi, San Luis Potosi city0.016730See
MEXMexico Chihuahua Rural0.0167236See
BRABrazil REDOME Rio Grande do Norte0.016746603See
MEXMexico Oaxaca, Oaxaca city0.0166151See
BRABrazil REDOME Sao Paulo0.0165800809See
BRABrazil REDOME Parana0.0162341639See
BRABrazil REDOME Rio de Janeiro0.0161139322See
ARGArgentina Corrientes3.20.0160155See
HRVCroatia Gorski Kotar Region0.016063See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.016094See
BRABrazil REDOME Rio Grande do Sul0.0158241329See
BRABrazil REDOME Minas Gerais0.0157211275See
GBRUnited Kingdom East0.0157163See
NORNorway ethnic Norwegians3.10.01574510See
GBRUnited Kingdom South West0.0156163See
BRABrazil REDOME Sergipe0.01567321See
BRABrazil REDOME Espirito Santo0.015588485See
GBRUnited Kingdom North0.0153330See
BRABrazil Southeast Campinas Mixed3.00.015199See
GBRUnited Kingdom pop 20.0150101See
BRABrazil Sao Paulo Bauru Mixed0.01503542See
ARMArmenia living in Karabakh0.0150445See
RUSRussia Samara Region0.01502500See
SWESweden Stockholm2.90.01501347See
SWESweden pop 43.00.0150966See
UKRUkraine Lvov0.0150102See
MEXMexico Zacatecas Rural0.0149266See
MEXMexico Sinaloa, Culiacán0.0146103See
ENGEngland Sheffield2.80.01414755See
DEUGermany Essen2.90.0140174See
BRABrazil Rio Grande do Sul Caucasoid0.01404428See
MEXMexico Puebla, Puebla city0.01401994See
RUSRussia South Ural Russian2.90.0140207See
RUSRussia Moscow0.01402650See
NORNorway pop 20.0140576See
MEXMexico Jalisco, Guadalajara city0.01381189See
MEXMexico Mexico City Metropolitan Area Rural0.0132150See
INDIndia Northeast Sunni0.0130188See
INDIndia Northeast Mathur0.0130155See
MEXMexico Mestizo pop 40.0130269See
ARMArmenia Shirak0.013076See
BRABrazil Parana Afro Brazilian2.60.013077See
CHLChile Huilliche0.013040See
USAUSA OPTN Hispanic0.01301580See
MEXMexico Durango, Durango city0.0129153See
MEXMexico Guanajuato, Leon0.012878See
BRABrazil REDOME Santa Catarina0.0124106673See
MEXMexico Hidalgo Rural0.012381See
RUSRussia Moscow Pop 22.50.01232000See
FRAFrance Rennes pop 42.40.01211000See
INDIndia Lucknow2.50.0120123See
ENGEngland Leeds2.40.01205024See
ARMArmenia Ghegharkunik0.0120242See
RUSRussia Northwest2.30.01201011See
RUSRussia Northwest pop 22.30.0120346See
PRTPortugal Faro0.01201242See
USAUSA OPTN Caucasian0.01208525See
KURIraq Kurdistan Region2.40.0120209See
WALWales pop 22.40.012039979See
ENGEngland North West Mixed pop 22.40.0119379See
MEXMexico Jalisco, Zapopan0.0119168See
MEXMexico Queretaro Rural0.011643See
FRAFrance Marseille2.30.01151000See
MMRMyanmar Kayin2.30.011444See
BRABrazil Parana Caucasian2.20.01102775See
MMRMyanmar Bamar2.20.010946See
ITAItaly pop 62.20.0109184See
ESPSpain Valencia2.10.0105577See
ENGEngland Newcastle2.10.01052739See
ENGEngland Manchester2.10.01051640See
MEXMexico Jalisco Rural0.0102585See
MEXMexico Baja California Rural0.010050See
MEXMexico Puebla Mestizo0.010099See
INDIndia New Delhi pop 20.0100102See
FRAFrance West Breton0.0100150See
INDIndia Uttar Pradesh0.0100202See
AUSAustralia West Caucasian1.90.0100891See
PAKPakistan Mixed Pathan0.0100100See
PRTPortugal Aveiro0.01005933See
RUSRussia Northwest Slavic0.0100200See
TURTurkey pop 10.0100250See
TURTurkey Ankara0.010050See
MEXMexico Michoacan, Morelia0.0099150See
FRAFrance Lyon1.90.00944813See
MEXMexico Guanajuato Rural0.0092162See
ARMArmenia living in USA0.0090233See
PRTPortugal Evora0.0090737See
PRTPortugal Porto0.00907937See
PRTPortugal Viseu0.00902915See
PRTPortugal Beja0.0090699See
PRTPortugal North pop 20.00881801See
ENGEngland Liverpool1.70.00851343See
HRVCroatia pop 31.70.0083120See
ALBAlbanian Kosovo0.0083120See
MEXMexico Tlaxcala, Tlaxcala city0.0083181See
IRQIraq Erbil1.60.0081372See
INDIndia Bikaner Raikas1.50.0080143See
MEXMexico Mexico City Mestizo0.0080121See
GRCGreece North0.0080500See
GRCGreece pop21.60.0080120See
FRAFrance Southeast1.50.0080130See
FRAFrance Grenoble, Nantes and Rennes0.00806094See
ESPSpain Murcia0.0080173See
PRTPortugal Braga0.00801971See
PRTPortugal Center pop 20.0080562See
PRTPortugal Coimbra0.00805057See
MMRMyanmar Kachin1.60.007963See
MEXMexico Nayarit Rural0.007864See
MEXMexico Puebla Rural0.0078833See
MEXMexico Durango Rural0.0076326See
MEXMexico Sonora Rural0.0076197See
POLPoland pop 31.50.00762907See
MEXMexico Coahuila, Torreon0.0075396See
MEXMexico Yucatan Rural0.0075132See
INDIndia North Gujarat1.50.0075338See
ENGEngland Lancaster1.50.0075545See
SAUSaudi Arabia pop 41.40.0072499See
SVKSlovakia pop 20.00714234See
ESPSpain, Castilla y Leon, Northwest,0.60.00711743See
ESPSpain Northwest1.40.00701818See
ESPSpain Minorca0.007094See
IRNIran Royan Cord Blood Bank1.40.007015600See
IRNIran pop 40.0070855See
USAUSA Philadelphia Caucasian1.40.0070141See
PRTPortugal Viana do Castelo0.0070706See
PRTMadeira pop 30.0070538See
RUSRussia Kostroma Region0.0070126See
FRAFrance Bordeaux1.40.0069990See
IRQIraq Arabs1.30.0067149See
MEXMexico Veracruz Rural0.0065539See
INDIndia sub-Himalayan West Bengal Kami1.30.0063158See
IRLIreland South pop 20.006317624See
MEXMexico Mexico City East0.006379See
ITAItaly North Pavia pop 30.0062685See
TURTurkey Istanbul1.20.0061250See
RUSRussia Smolensk0.0060156See
PRTPortugal Setubal0.00605268See
PRTPortugal Lisbon0.006017420See
PRTPortugal Vila Real0.00601167See
ITAItaly Sardinia0.006086See
MEXMexico Tlaxcala Rural0.0060830See
ISRIsrael Non Ashkenazi Jews0.006080See
CAFCentral African Republic Aka Pygmy1.20.006093See
CZECzech Republic pop 31.10.0060180See
ARMArmenia living in Iran0.006085See
FRAFrance Grenoble1.10.00571000See
INDIndia North pop 30.0051587See
SDNSudan Khartoum0.005198See
SRBSerbia Vojvodina1.00.0050400See
PRTPortugal Leiria0.00501847See
PRTPortugal Santarem0.00503865See
PRTPortugal Castelo Branco0.0050327See
PRTPortugal Guarda0.0050797See
IRLIreland Donegal1.00.0050200See
IRLIreland Wexford1.00.0050200See
ISRIsrael Iranian Jews0.0050101See
MEXMexico Guanajuato and Jalisco Mestizo1.00.0050101See
LKASri Lanka Colombo Sinhalese0.0050101See
ESPSpain Madrid1.00.0050504See
ESPSpain Majorca0.0050407See
ARMArmenia Lori0.0050102See
ARMArmenia Yerevan0.0050445See
MEXMexico Chihuahua, Ciudad Juarez0.0046106See
ROMRomania pop 30.80.00411469See
PRTPortugal Portalegre0.00401254See
PRTPortugal South pop 20.00401021See
UKRUkraine Khmelnytskyi0.0040138See
ITAItaly North Pavia pop 20.70.00402416See
INDIndia Bikaner Non-Raikas0.80.0040127See
AREUnited Arab Emirates pop 20.80.0040373See
ARMArmenia Syunik0.0040117See
ARMArmenia living in Lebanon0.0040368See
BRABrazil Kaingang0.0040235See
FRAFrance South0.80.0040350See
SRBSerbia pop 30.80.00381992See
MEXMexico Tabasco Rural0.0035142See
MEXMexico Guerrero state0.0035144See
GRCGreece pop 70.003411250See
BGDBangladesh Dhaka Bangalee0.0030141See
ITAItaly Lombardy0.60.0030674See
MEXMexico Highlands Mestizos0.60.0030160See
ITAItaly North pop 20.60.00302054See
ISRIsrael Jews pop 20.60.003023000See
PRTPortugal Bragança0.0030301See
MEXMexico Michoacan Rural0.0029348See
MEXMexico Veracruz, Xalapa0.0027187See
MEXMexico Nuevo Leon, Monterrey city0.0022226See
MEXMexico Mexico City North0.0020751See
GRCGreece pop 50.0020500See
MKDMacedonia MBMDR - Macedonian0.30.00161283See
ITAItaly Central0.0010380See
ITAItaly Sardinia pop20.10.00101129See
SAUSaudi Arabia pop 20.0010383See
ITAItaly South Campania Region0.10.00051089See
ITAItaly pop 20.000053See
MARMorocco pop 20.0000110See
MEXMexico Huasteca Region Teenek0.000055See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Morelos Rural0.000030See
MEXMexico Baja California, Tijuana0.000025See
ISRIsrael Libyan Jews0.0000119See
ITAItaly North pop 30.00.000097See
ISRIsrael Ethiopian Jews0.0000122See
ISRIsrael Yemenite Jews0.000076See
ISRIsrael Arab0.0000109See
MEXMexico Mexico City Center0.0000152See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Mexico City South0.000052See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Colima, Colima city0.000061See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Tamaulipas Rural0.0000125See
HRVCroatia pop 20.0000100See
INDIndia Tamil Nadu Dravidian0.0000156See
INDIndia Tamil Nadu Chennai0.00.0000137See
ESPSpain Malaga Romani0.00.000080See
ESPSpain Malaga0.00.0000160See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
DZAAlgeria pop 20.00.0000106See
BIHBosnia and Herzegovina0.0000134See
BLRBelarus Vitebsk Region0.000070See
BFABurkina Faso Fulani0.000049See
BLRBelarus Gomel Region0.0000100See
BORBorneo Bandjarmasin0.000021See
ROMRomania pop 20.00006936See
PNGPapua New Guinea East New Britain Tolai0.000048See
PNGPapua New Guinea Highland pop20.000028See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
SDNSudan Mixed0.00.0000200See
TTOTrinidad South Asian0.000087See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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