Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 124 time(s) and present in 52 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MYSMalaysia Jelebu Temuan0.063025See
CHNChina Guizhou Province Miao0.036085See
CHNChina Yunnan Province Yao0.032066See
THAThailand Bangkok pop 20.030050See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0290138See
CHNChina Han Guandong Province0.0220208See
TWNTaiwan Han0.020050See
TWNTaiwan Hakka3.60.018055See
TWNTaiwan Thao3.30.017030See
USAUSA NMDP Vietnamese0.014643540See
HKGHong Kong Chinese cord blood registry0.01253892See
HKGHong Kong Chinese BMDR0.01217595See
VNMVietnam HoaBinh Muong0.012083See
CHNChina Lijiang Naxi0.0110100See
CHNChina Yunnan Province Lisu0.0100111See
COKCook Islands0.010050See
CHNChina Hubei Han2.00.00983732See
CHNChina Yunnan Province Lahu0.009070See
USAUSA NMDP Chinese0.008199672See
TWNTaiwan Minnan and Hakka0.0080190See
CHNChina Canton Han0.0080264See
CHNChina Yunnan Province Bai0.0080128See
CHNChina Marrow Donor Registry0.0080600See
STPSao Tome Island Forro0.008066See
CHNChina Zhejiang Han pop 20.0078833See
MYSMalaysia Peninsular Chinese1.60.0077194See
CHNChina Jiangsu Province Han0.0074334See
TWNTaiwan Han Chinese0.0060504See
TWNTaiwan pop 20.0060364See
VNMVietnam Hanoi Kinh0.0050103See
CHNChina Yunnan Province Nu0.0050107See
TWNTaiwan Minnan pop 11.00.0050102See
DEUGermany DKMS - China minority0.00471282See
TWNTaiwan Tzu Chi Morrow Donor Registry0.004546682See
USAUSA Asian pop 20.00421772See
CHNChina Jiangsu Han0.00313238See
RUSRussia Tuva pop 20.0030169See
TWNTaiwan Tzu Chi Cord Blood Bank0.0030710See
USAUSA NMDP Southeast Asian0.002427978See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0022233See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
JPNJapan pop 30.00101018See
USAUSA San Diego0.20.0010496See
USAUSA NMDP Filipino0.000350614See
USAUSA NMDP Hawaiian or other Pacific Islander0.000111499See
USAUSA NMDP South Asian Indian0.0001185391See
USAUSA NMDP Hispanic South or Central American0.0001146714See
USAUSA NMDP Korean0.000177584See
USAUSA NMDP Mexican or Chicano0.0000261235See
USAUSA NMDP African American pop 20.0000416581See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA Hispanic pop 20.00001999See
WSMSamoa pop20.000050See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American pop 40.00002411See
TWNTaiwan Tsou pop 20.000050See
TWNTaiwan Paiwan pop 20.000050See
TWNTaiwan Rukai pop 20.000050See
TWNTaiwan Orchid Island Yami0.000050See
TWNTaiwan Ami pop 20.000050See
TWNTaiwan Puyuma pop 20.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Atayal pop 20.000050See
TWNTaiwan Saisiat pop 20.000050See
TWNTaiwan Bunun pop 20.000050See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Caucasian Pittsburgh0.00.0000177See
ESPSpain Barcelona0.00.0000941See
ESPSpain Murcia0.0000173See
FRAFrance West0.00.0000100See
CODCongo Kinshasa Bantu0.00.000090See
COLColombia Bogota and Medellin Mestizo0.000065See
CZECzech Republic0.0000106See
CHNChina Jiangxi Province0.000098See
CHNChina Yunnan Province Drung0.000070See
CHNChina Urumqi Uyghur0.00.000057See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
BRABrazil North East Mixed0.0000205See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Caucasian0.00.0000103See
BRABrazil Southeast Mixed Race0.00.000042See
CAFCentral African Republic Aka Pygmy0.00.000093See
KORSouth Korea pop 20.00.0000207See
KORSouth Korea pop 30.0000485See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
MEXMexico Highlands Mestizos0.00.0000160See
MEXMexico Nuevo Leon Mestizo0.00.000040See
MKDMacedonia pop 10.0000158See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PHLPhilippines Ivatan0.00.000050See
PRYParaguay Lengua0.000017See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
ITAItaly pop 50.0000975See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
DEUGermany pop 80.000039689See
STPSao Tome Island Angolar0.000032See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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