Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.

   

B*35:12

Allele reported 110 time(s) and present in 61 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
MEXMexico Mixtec NA-DHS_5 (G)45.00.250020See
MEXMexico Oaxaca Mixe0.240055See
COLColombia Wayuu NA-DHS_15 (G)33.30.166715See
MEXMexico Oaxaca Mixtec0.1570103See
MEXMexico Mixe NA-DHS_6 (G)30.00.150020See
MEXMexico Chiapas Lacandon Mayans0.1101218See
GTMGuatemala Kaqchikel NA-DHS_8 (G)21.10.105319See
MEXMexico Tixcacaltuyub Maya0.104567See
MEXMexico Zapotec NA-DHS_7 (G)17.60.088220See
VENVenezuela Sierra de Perija Yucpa0.081073See
MEXMexico Mestizo12.20.061041See
MEXMexico Oaxaca Zapotec0.052090See
MEXMexico Guadalajara Mestizo pop 20.0490103See
MEXMexico Mexico City Mestizo population0.0455143See
MEXMexico Mexico City Mestizo pop 20.0385234See
COLColombia Embera NA-DHS_19 (G)7.10.035714See
COLColombia Zenu NA-DHS_18 (G)6.30.031316See
USAUSA South Texas Hispanic0.0300194See
COLColombia Arhuaco NA-DHS_16 (G)5.90.029417See
COLColombia Bogotá Cord Blood5.50.02841463See
NICNicaragua Managua4.80.0241339See
USAUSA Hispanic0.0240234See
USAUSA Mexican American Mestizo0.0230553See
USAUSA NMDP Mexican or Chicano0.0223261235See
MEXMexico Chichen Itza Maya (prehispanic)0.021347See
MEXMexico Mixtec0.021097See
MEXMexico Oaxaca Jamiltepec Mixtec0.021096See
COLColombia North Wiwa El Encanto0.019252See
USAUSA Hispanic pop 20.01901999See
USAUSA NMDP Hispanic South or Central American0.0179146714See
BRABrazil Mixed0.0140108See
PANPanama0.0121462See
CUBCuba Mixed Race2.40.012042See
INDIndia West Coast Parsi0.010050See
USAUSA NMDP Caribean Hispanic0.0081115374See
USAUSA NMDP Caribean Indian0.008014339See
USAUSA San Diego1.00.0050496See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0050146See
CHLChile Santiago Mixed1.00.005070See
USAUSA NMDP American Indian South or Central America0.00405926See
USAUSA Philadelphia Caucasian0.70.0040141See
USAUSA North American Native0.0030187See
USAUSA Spain Ancestry0.0020279See
USAUSA Alaska Yupik0.0020252See
USAUSA Eastern European0.0010558See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA NMDP North American Amerindian0.000835791See
USAUSA NMDP Hawaiian or other Pacific Islander0.000611499See
USAUSA NMDP Caribean Black0.000533328See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00034335See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
USAUSA NMDP African American pop 20.0001416581See
USAUSA NMDP European Caucasian0.00011242890See
USAUSA NMDP Filipino0.000150614See
USAUSA NMDP African0.000128557See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Southeast Asian0.000027978See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP Japanese0.000024582See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP Chinese0.000099672See
USAUSA African American pop 80.0000605See
USAUSA African American pop 40.00002411See
USAUSA Asian pop 20.00001772See
USAUSA Asian0.0000358See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA European American pop 20.00001245See
ZAFSouth Africa Natal Zulu0.00.0000100See
HKGHong Kong Chinese0.00.0000569See
HRVCroatia0.0000150See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
ITAItaly Bergamo0.00.0000101See
ITAItaly pop 50.0000975See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
BGRBulgaria0.000055See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
DEUGermany pop 80.000039689See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
OMNOman0.00.0000118See
PHLPhilippines Ivatan0.00.000050See
ROMRomania0.00.0000348See
SGPSingapore Chinese0.00.0000149See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA San Antonio Caucasian0.0000222See

See also higher resolution data of this allele


Allele  Number of Populations 
 B*35:12:01 
 B*35:12:02 
 B*35:121 
 B*35:123 
 B*35:124 
 B*35:125 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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