Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 255 time(s) and present in 126 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SENSenegal Dakar16.10.0760112See
SDNSudan East Rashaida11.10.057127See
VENVenezuela Colonia Tovar0.034986See
ROMRomania pop 20.03006936See
CUBCuba Mixed pop 20.0160189See
GRCGreece pop32.80.0141246See
ESPSpain North Cabuerniga0.013095See
COLColombia San Basilio de Palenque0.012042See
USAUSA African American Bethesda2.10.0110187See
USAUSA OPTN African American0.01101510See
IRQIraq Arabs2.00.0101149See
VENVenezuela Caracas Mestizo0.010050See
TTOTrinidad African0.010067See
MEXMexico Quintana Roo Rural0.010050See
PAKPakistan Mixed Pathan0.0100100See
MARMorocco pop 20.0090110See
MEXMexico Nayarit Rural0.007864See
GBRUnited Kingdom Central0.0075135See
MEXMexico Hidalgo Rural0.006281See
PRTPortugal Castelo Branco0.0060327See
GBRUnited Kingdom Orkney0.006088See
MEXMexico Veracruz, Veracruz city0.0058171See
MKDMacedonia pop 40.0050216See
MEXMexico Puebla Mestizo0.005099See
BRABrazil Pernambuco Mixed0.0050101See
TZATanzania Dodoma Kongwa0.0050212See
ESPSpain Pas Valley0.005088See
PAKPakistan Burusho0.005092See
GBRUnited Kingdom North0.0046330See
ALBAlbania pop 20.90.0046432See
MEXMexico Chihuahua Chihuahua City0.0042119See
BRABrazil Para Cord Blood Unit0.00.0042841See
MEXMexico Chiapas Rural0.0041121See
PRTPortugal Evora0.0040737See
GTMGuatemala, Guatemala City Mixed Ancestry0.80.0039127See
MEXMexico Yucatan Rural0.0037132See
MEXMexico Guerrero state0.0035144See
MEXMexico Oaxaca, Oaxaca city0.0033151See
BRABrazil REDOME Para0.003272637See
INDIndia sub-Himalayan West Bengal Kami0.60.0032158See
GBRUnited Kingdom East0.0031163See
MKDMacedonia pop 30.0030172See
PRTPortugal Center pop 20.0030562See
PRTPortugal Santarem0.00303865See
COLColombia Barranquilla0.0030188See
BRABrazil Parana Cafuzo0.60.0030319See
BGDBangladesh Dhaka Bangalee0.0030141See
ARGArgentina Buenos Aires0.60.0030466See
BRABrazil REDOME Amapa0.003017864See
CHLChile Santiago0.0027920See
ROMRomania pop 30.50.00271469See
MEXMexico Coahuila, Torreon0.0025396See
ECUEcuador Coast Mixed Ancestry0.0021238See
ARGArgentina Cuyo Region0.50.0020420See
BRABrazil Para State0.20.00205000See
PRTPortugal Porto0.00207937See
PRTPortugal Guarda0.0020797See
PRTPortugal Braga0.00201971See
PRTPortugal Bragança0.0020301See
USAUSA OPTN Hispanic0.00201580See
MEXMexico Veracruz Rural0.0018539See
BRABrazil REDOME Acre0.0018859See
BRABrazil REDOME Bahia0.001747399See
BRABrazil REDOME Maranhao0.001510180See
MEXMexico Durango Rural0.0015326See
PRTPortugal North pop 20.00151801See
MEXMexico Michoacan Rural0.0014348See
BRABrazil Rio Grande do Sul Caucasoid0.00144428See
BRABrazil REDOME Tocantins0.001320692See
BRABrazil REDOME Piaui0.001346140See
MEXMexico Puebla, Puebla city0.00131994See
BRABrazil REDOME Rio de Janeiro0.0012139322See
BRABrazil REDOME Mato Grosso0.001234649See
BRABrazil REDOME Ceara0.0012101217See
BRABrazil REDOME Amazonas0.001224129See
BRABrazil REDOME Rio Grande do Norte0.001246603See
BRABrazil REDOME Pernambuco0.001192332See
BRABrazil South East Cord Blood0.001111409See
BRABrazil Piaui Mixed0.001021943See
BRABrazil Rio Grande do Norte Mestizo0.001012973See
AUSAustralia West Caucasian0.10.0010891See
BRABrazil Minas Gerais State Mixed0.20.00101000See
BRABrazil Parana Caucasian0.10.00102775See
MEXMexico Oaxaca Rural0.0010485See
SAUSaudi Arabia pop 20.0010383See
PRTMadeira pop 30.0010538See
PRTPortugal Faro0.00101242See
PRTPortugal Coimbra0.00105057See
PRTPortugal South pop 20.00101021See
PRTPortugal Aveiro0.00105933See
PRTPortugal Beja0.0010699See
PRTPortugal Leiria0.00101847See
PRTPortugal Lisbon0.001017420See
PRTPortugal Portalegre0.00101254See
PRTPortugal Setubal0.00105268See
PRTPortugal Viana do Castelo0.0010706See
PRTPortugal Vila Real0.00101167See
PRTPortugal Viseu0.00102915See
WALWales pop 20.00.001039979See
BRABrazil REDOME Sergipe0.00097321See
BRABrazil REDOME Santa Catarina0.0009106673See
BRABrazil REDOME Federal District0.000929549See
BRABrazil REDOME Goias0.000988574See
BRABrazil REDOME Minas Gerais0.0009211275See
GRCGreece pop 70.000911250See
MEXMexico Jalisco, Guadalajara city0.00081189See
BRABrazil REDOME Mato Grosso do Sul0.000895667See
BRABrazil REDOME Rondonia0.000854396See
BRABrazil REDOME Paraiba0.000743868See
BRABrazil REDOME Sao Paulo0.0007800809See
ESPSpain, Castilla y Leon, Northwest,0.20.00071743See
BRABrazil REDOME Parana0.0006341639See
BRABrazil REDOME Espirito Santo0.000688485See
BRABrazil REDOME Alagoas0.000625349See
BRABrazil REDOME Rio Grande do Sul0.0005241329See
BRABrazil REDOME Roraima0.00054140See
SWESweden pop 40.10.0005966See
ECUEcuador Mixed Ancestry0.00041173See
MKDMacedonia MBMDR - Macedonian0.10.00041283See
ISRIsrael Jews pop 20.10.000323000See
FRAFrance Lyon0.00.00024813See
FRAFrance Grenoble, Nantes and Rennes0.00006094See
FRAFrance Rennes pop 30.0000200See
ECUEcuador Amazonia Mixed Ancestry0.000039See
ECUEcuador Andes Mixed Ancestry0.0000824See
CZECzech Republic0.0000106See
HRVCroatia pop 20.0000100See
CHNChina North Han0.0000105See
CHNChina Jiangsu Province0.000020248See
CHNChina Shanghai0.000026266See
CHNChina Shandong Province0.00.00007418See
BRABrazil Sao Paulo Bauru Mixed0.00003542See
BRABrazil Sao Paulo Mixed0.00.0000239See
BRABrazil Parana Mixed race0.00.0000186See
BRABrazil Parana Afro Brazilian0.00.000077See
BRABrazil Parana Oriental0.00.000033See
BIHBosnia and Herzegovina0.0000134See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
ARGArgentina Buenos Aires pop 20.00.00001216See
ARGArgentina Corrientes0.00.0000155See
ARGArgentina La Plata0.00.0000100See
ITAItaly South Campania Region0.00.00001089See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
ITAItaly North Pavia pop 20.00.00002416See
KORSouth Korea pop 80.00007096See
GRCGreece North0.0000500See
IRNIran Royan Cord Blood Bank0.00.000015600See
IRLIreland South pop 20.000017624See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Mexico City North0.0000751See
MEXMexico Mexico City East0.000079See
MEXMexico Mexico City Center0.0000152See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Sinaloa Mestizo0.000056See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
MYSMalaysia pop 20.000062See
MEXMexico Mexico City Mestizo0.0000121See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
TTOTrinidad South Asian0.000087See
TURTurkey pop 50.0000142See
AREUnited Arab Emirates pop 20.00.0000373See
GBRUnited Kingdom South West0.0000163See
SDNSudan Mixed0.00.0000200See
ZAFSouth Africa Natal Zulu0.00.0000100See
ESPSpain Majorca0.0000407See
ESPSpain Minorca0.000094See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ESPSpain Murcia0.0000173See
USAUSA South Texas Hispanic0.0000194See
USAUSA OPTN Caucasian0.00008525See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA OPTN Asian0.0000261See
SCOScotland Orkney0.00.000099See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
RUSRussia Moscow0.00002650See
RUSRussia South Ural Russian0.00.0000207See
RUSRussia South Ural Bashkir0.00.0000146See
RUSRussia South Ural Tatar0.00.0000135See
RUSRussia Northwest pop 30.00.0000100See
MEXMexico Morelos Rural0.000030See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Jalisco Rural0.0000585See
MEXMexico Campeche Rural0.000047See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Sindhi0.0000101See
PRTPortugal North0.000046See
PAKPakistan Karachi Parsi0.000091See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Tlaxcala Rural0.0000830See
MEXMexico Puebla Rural0.0000833See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Zacatecas Rural0.0000266See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See

See also higher resolution data of this allele

Allele  Number of Populations 
 B*78:01 108 
 B*78:02 54 
 B*78:02:01 10 
 B*78:03 29 
 B*78:04 19 
 B*78:05 15 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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