Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 74 time(s) and present in 37 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CMRCameroon Ewondo0.079038See
SENSenegal Niokholo Mandenka0.0250165See
GNQEquatorial Guinea Bioko Island Bubi0.0250100See
VENVenezuela Zulia Maracaibo Mixed0.025020See
VENVenezuela Zulia San Jose de Heras Mixed0.025020See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.021096See
CMRCameroon Bamileke 20.014035See
POLPoland North2.50.012580See
MEXMexico Mexico City Mestizo pop 30.0120256See
ENGEngland North West Mixed pop 21.90.0092379See
ALBAlbanian Kosovo0.0083120See
MEXMexico Tapachula, Chiapas Mestizo Population1.40.006972See
SAUSaudi Arabia pop 41.00.0051499See
BRABrazil Pernambuco Mixed0.0050101See
ITAItaly Rome1.00.0050100See
ARGArgentina La Plata1.00.0040100See
SRBSerbia pop 30.60.00321992See
ARGArgentina Buenos Aires0.60.0030466See
BRABrazil Parana Japanese1.00.0026192See
CHESwitzerland Graubunden0.0024759See
ESPSpain, Castilla y Leon, Northwest,0.20.00141743See
FRAFrance Grenoble0.20.00101000See
RUSRussia Moscow0.00102650See
WALWales pop 20.00.001039979See
ENGEngland London Ashkenazi Jews0.0010500See
ESPSpain Galicia and Murcia0.20.0010473See
ITAItaly North Pavia pop 30.0009685See
PRTPortugal North pop 20.00081801See
GRCGreece pop 70.000711250See
FRAFrance Bordeaux0.10.0005990See
ENGEngland Sheffield0.10.00054755See
FRAFrance Lyon0.10.00044813See
NORNorway ethnic Norwegians0.10.00034510See
POLPoland Wroclaw0.00.0000123See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CMRCameroon Uldeme0.000035See
CMRCameroon Podokwo0.000043See
RUSRussia Northwest pop 30.00.0000100See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHNChina North Han0.0000105See
CHNChina Inner Mongolia Region0.0000102See
CHNChina Qinghai Province Hui0.0000110See
ROMRomania pop 20.00006936See
FRAFrance Grenoble, Nantes and Rennes0.00006094See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.000094See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
MYSMalaysia Perak Rawa0.000023See
ESPSpain Majorca0.0000407See
ESPSpain Minorca0.000094See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ESPSpain Murcia0.00.0000173See
CHESwitzerland Geneva0.000080See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
USAUSA South Texas Hispanic0.0000194See
CZECzech Republic0.0000106See
FRAFrance West0.00.0000100See
USAUSA African American Bethesda0.00.0000187See
MKDMacedonia pop 40.0000216See

See also higher resolution data of this allele

Allele  Number of Populations 
 C*18:01 120 
 C*18:02 24 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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