Allele Frequencies in World Populations

HLA Database Breakdowns

Summary

To summarise HLA data stored in the Allele Frequency Net Database we have classified alleles grouped by Locus. Most frequently alleles are listed on the right side.
   

HLA Alleles


Locus Alleles
(IMGT/HLA)
 HLA-A 3,094
 HLA-B 3,866
 HLA-C 2,618
 HLA-DMA 7
 HLA-DMB 13
 HLA-DOA 12
 HLA-DOB 13
 HLA-DPA1 39
 HLA-DPB1 520
 HLA-DQA1 54
 HLA-DQB1 777
 HLA-DRA 7
 HLA-DRB1 1,719
 HLA-DRB2 1
 HLA-DRB3 59
 HLA-DRB4 15
 HLA-DRB5 21
 HLA-DRB6 3
 HLA-DRB7 2
 HLA-DRB8 1
 HLA-DRB9 1
 HLA-E 17
 HLA-F 22
 HLA-G 50
 HLA-H 12
 HLA-J 9
 HLA-K 6
 HLA-L 5
 HLA-P 5
 HLA-V 3
 HLA-Y 3
Total 12,974




          



          
 

Top HLA Allele Entries


Allele Total Entries
 HLA-DRB1*03:01 510
 HLA-DQB1*03:01 501
 HLA-DQB1*03:02 499
 HLA-B*35 463
 HLA-B*51 460
 HLA-B*07 457
 HLA-B*44 455
 HLA-A*24 453
 HLA-A*02 450
 HLA-A*33 447
 HLA-DRB1*07 445
 HLA-A*03 445
 HLA-B*39 443
 HLA-B*13 442
 HLA-DRB1*01:01 441
 HLA-B*27 438
 HLA-A*11 438
 HLA-DRB1*15:01 438
 HLA-DRB1*13:01 435
 HLA-DRB1*08 435
 HLA-A*01 434
 HLA-B*18 433
 HLA-B*57 433
 HLA-DRB1*04:03 430
 HLA-DRB1*09 428
 HLA-A*26 427
 HLA-B*08 426
 HLA-DRB1*10:01 424
 HLA-B*55 423
 HLA-DRB1*11:01 423

 


Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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