Allele Frequencies in World Populations

HLA Database Breakdowns

Summary

To summarise HLA data stored in the Allele Frequency Net Database we have classified alleles grouped by Locus. Most frequently alleles are listed on the right side.
   

HLA Alleles


Locus Alleles
(IMGT/HLA)
 HLA-A 3,094
 HLA-B 3,866
 HLA-C 2,618
 HLA-DMA 7
 HLA-DMB 13
 HLA-DOA 12
 HLA-DOB 13
 HLA-DPA1 39
 HLA-DPB1 520
 HLA-DQA1 54
 HLA-DQB1 777
 HLA-DRA 7
 HLA-DRB1 1,719
 HLA-DRB2 1
 HLA-DRB3 59
 HLA-DRB4 15
 HLA-DRB5 21
 HLA-DRB6 3
 HLA-DRB7 2
 HLA-DRB8 1
 HLA-DRB9 1
 HLA-E 17
 HLA-F 22
 HLA-G 50
 HLA-H 12
 HLA-J 9
 HLA-K 6
 HLA-L 5
 HLA-P 5
 HLA-V 3
 HLA-Y 3
Total 12,974




          



          
 

Top HLA Allele Entries


Allele Total Entries
 HLA-DRB1*03:01 507
 HLA-DQB1*03:01 498
 HLA-DQB1*03:02 495
 HLA-DRB1*01:01 464
 HLA-DRB1*15:01 461
 HLA-DRB1*13:01 459
 HLA-DRB1*04:03 457
 HLA-DRB1*04:04 454
 HLA-DRB1*10:01 448
 HLA-DRB1*11:01 446
 HLA-B*35 446
 HLA-DRB1*07:01 445
 HLA-B*51 443
 HLA-B*07 439
 HLA-DRB1*14:01 439
 HLA-DRB1*13:02 437
 HLA-A*24 436
 HLA-B*44 435
 HLA-A*02 433
 HLA-A*33 427
 HLA-A*03 427
 HLA-B*39 425
 HLA-DRB1*07 424
 HLA-B*27 421
 HLA-B*13 420
 HLA-A*11 420
 HLA-DRB1*12:01 419
 HLA-B*18 415
 HLA-A*01 415
 HLA-DRB1*04:05 413

 


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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