 |
HLA Database >> Rare Alleles
This module describes all classical HLA alleles registered on the IMGT/HLA Database
as of Release 3.37.0 and the
number of times that each allele has been reported to different databases such as the
Allele Frequency Net Database (AFND), the
National Marrow Donor Program (NMDP) in the US
as of Release 3.9.0 and other individual laboratories.
The aim of this page is that a user can identify HLA rare alleles by filtering the total times an HLA allele has been reported
to these Databases.
E.g. Cells < 3, Groups < 3, Pops < 2, NMDP < 2, Labs < 2.
Contribute to this project
Dear Colleagues
We would like to thank your contribution to the Rare HLA Alleles project, which was considered as part of the past 15th and 16th International HLA and Immunogenetics Workshops (IHIWS) in Buzios and Liverpool respectively. Since last workshop we have been receiving confirmations of rare alleles which data is deposited into the Allele Frequency Net Database (AFND, www.allelefrequencies.net). Some of the contributors have sent data in spreadsheets and others have submitted data directly using the AFND website. As a continuation of this project, we invite people to participate in the project entitled "Study of rare alleles and novel HLA alleles by NGS HLA" which is part of the 17th IHIWS, to be held in Pacific Grove, CA, USA from 6-10 September 2017 (www.ihiws.org). You can either submit data on an allele that has been sequenced in your laboratory or you may submit material and the allele will be typed by NGS. We also can provide a tool for filtering your rare alleles from a file of individual types. We need your help to ensure this project is successful.
If an allele that we consider to be rare has been typed in your laboratory, please report it by clicking on the "
" image beside the allele.
Basic information will be required to complete your submissions. Your contribution is vital to confirm the number of rare alleles!.
Click here to see the list of current contributors.New tool: Rare Allele Detector
To facilitate the analysis of large datasets (i.e. 1000 individuals typed) the Rare Allele Detector tool has been incorporated to the AFND website. This tool simplifies the detection of alleles which are considered to be very rare, rare or frequent. Click here to try this tool.
How to browse
Rare alleles can be filtered according to how many times it is since they were first sequenced. Please select your criteria by using different options and click "Search".
| Displaying 10,891 to 10,920 (from 12,689) records | Pages:
  361 362 363 364 365 366 367 368 369 370 of 423 
|
 |
| Displaying 10,891 to 10,920 (from 12,689) records | Pages: |
|
|
361 362 363 364 365 366 367 368 369 370 of 423 |
|
|
|
Report Information
|
||||||||||||||||||||||||||||||||||||
Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.
support@allelefrequencies.net