Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 214 time(s) and present in 160 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Druze0.18555914See
ISRIsrael Tunisia Jews0.15279070See
ISRIsrael Ethiopia Jews0.11845928See
ISRIsrael Morocco Jews0.107236718See
CMRCameroon Bamileke0.104077See
ISRIsrael YemenJews0.104015542See
SENSenegal Niokholo Mandenka0.0910165See
GNBGuinea Bissau Bijago0.087023See
CMRCameroon Yaounde0.082092See
GNBGuinea Bissau Papel0.080025See
MLIMali Bandiagara0.0760138See
ISRIsrael Bukhara Jews0.07142317See
KENKenya Nandi0.0660240See
GNBGuinea Bissau Fula0.065031See
GHAGhana Ga-Adangbe12.20.0649131See
CRICosta Rica African -Caribbean (G)11.80.0640102See
GNBGuinea Bissau Balanta0.063048See
STPSao Tome Island Angolar0.063032See
GNBGuinea Bissau0.062065See
CMRCameroon Beti0.0600174See
BFABurkina Faso Rimaibe0.053047See
USAUSA NMDP African0.046628557See
STPSao Tome Island Forro0.045066See
USAUSA African American pop 40.04202411See
USAUSA NMDP Caribean Black0.041533328See
USAUSA NMDP African American pop 20.0414416581See
ARGArgentina Rosario Toba7.00.041086See
BRABrazil Mixed0.0400108See
USAUSA African American Bethesda7.90.0400187See
GEOGeorgia Svaneti Region Svan0.038080See
ISRIsrael Iran Jews0.03728153See
USAUSA African American pop 20.0370149See
UGAUganda Kampala pop 20.0370175See
MYSMalaysia Peninsular Malay6.90.0368951See
ZWEZimbabwe Harare Shona0.0360230See
ZAFSouth Africa Natal Zulu7.00.0350100See
ISRIsrael Iraq Jews0.034013270See
USAUSA African American0.0340252See
UGAUganda Kampala0.0340161See
KENKenya Luo0.0300265See
USAUSA African American pop 30.0290564See
PRTAzores Terceira Island0.0270130See
PRTPortugal Azores Terceira Island5.30.0263130See
TZATanzania Maasai5.10.0254336See
KENKenya, Nyanza Province, Luo tribe4.00.0250100See
MEXMexico Mexico City Tlalpan4.80.0242330See
SAUSaudi Arabia Guraiat and Hail4.20.0240213See
CPVCape Verde Southeastern Islands0.024062See
MYSMalaysia Peninsular Chinese4.60.0232194See
PAKPakistan Brahui0.0230104See
ZMBZambia Lusaka0.023044See
USAUSA NMDP Caribean Indian0.022014339See
ISRIsrael Arab Druze0.0200101See
USAUSA NMDP Caribean Hispanic0.0184115374See
SDNSudan Mixed3.50.0180200See
PRTAzores Central Islands0.018059See
MEXMexico Veracruz Xalapa3.60.017984See
PAKPakistan Karachi Parsi0.017091See
LBYLibya Cyrenaica0.0170118See
INDIndia Delhi pop 23.30.017090See
SAUSaudi Arabia pop 52.50.0158158See
CRICosta Rica Guanacaste Mestizo (G)2.80.0140110See
CHNChina Qinghai Province Hui0.0140110See
SDNSudan Central Shaigiya Mixed2.70.013536See
PRTAzores Oriental Islands0.013043See
CUBCuba Mixed Race2.40.012042See
AREUnited Arab Emirates Pop 10.0110570See
PRTPortugal North0.011046See
GEOGeorgia Tibilisi0.0100109See
ZAFSouth Africa Caucasians0.0100102See
ZAFSouth Africa Worcester2.00.0090159See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0090146See
CPVCape Verde Northwestern Islands0.008062See
USAUSA North American Native0.0080187See
CHLChile Mapuche0.007766See
USAUSA NMDP Hispanic South or Central American0.0076146714See
MARMorocco Settat Chaouya1.40.007098See
MARMorocco Atlantic Coast Chaouya0.007098See
USAUSA Hispanic pop 20.00681999See
USAUSA NMDP Middle Eastern or North Coast of Africa0.006070890See
SGPSingapore SGVP. Indian INS0.006086See
USAUSA Hispanic0.0060234See
USAUSA Caucasian pop 30.006088See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
MYSMalaysia Peninsular Indian1.10.0055271See
DEUGermany DKMS - Portugal minority0.00511176See
CZECzech Republic0.0050106See
MEXMexico Guadalajara Mestizo pop 20.0050103See
USAUSA Mexican American Mestizo0.0050553See
USAUSA NMDP Mexican or Chicano0.0041261235See
COLColombia Bogotá Cord Blood0.80.00411463See
ISRIsrael Arab pop 20.004012301See
ITAItaly pop 50.0040975See
FRAFrance Southeast0.80.0040130See
USAUSA Spain Ancestry0.0040279See
MEXMexico Mexico City Mestizo population0.0035143See
NICNicaragua Managua0.60.0030339See
NICNicaragua Mestizo (G)0.60.0030155See
DEUGermany DKMS - Italy minority0.00301159See
USAUSA NMDP American Indian South or Central America0.00305926See
USAUSA Asian0.0030358See
USAUSA San Diego0.60.0030496See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.50.00244335See
GRCGreece pop 60.0021242See
MEXMexico Mexico City Mestizo pop 20.0021234See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
USAUSA NMDP Alaska Native or Aleut0.00201376See
USAUSA Italy Ancestry0.0020273See
USAUSA South Dakota Lakota Sioux0.0020302See
DEUGermany DKMS - Turkey minority0.00194856See
CHNChina Jiangsu Province Han0.0018334See
ISRIsrael Ashkenazi Jews pop 30.00174625See
DEUGermany DKMS - Romania minority0.00161234See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00151028See
USAUSA NMDP North American Amerindian0.001435791See
USAUSA NMDP Hawaiian or other Pacific Islander0.001311499See
DEUGermany DKMS - Spain minority0.00141107See
DEUGermany DKMS - Greece minority0.00131894See
CZECzech Republic NMDR0.00125099See
ISRIsrael Argentina Jews0.00094307See
DEUGermany DKMS - United Kingdom minority0.00101043See
USAUSA Caucasian pop 40.00091070See
USAUSA NMDP European Caucasian0.00091242890See
DEUGermany pop 80.000839689See
DEUGermany DKMS - France minority0.00081406See
ISRIsrael USA Jews0.00076058See
ISRIsrael Poland Jews0.000613871See
DEUGermany DKMS - German donors0.00063456066See
DEUGermany DKMS - Austria minority0.00061698See
ISRIsrael USSR Jews0.000645681See
DEUGermany pop 60.00058862See
HRVCroatia pop 40.00044000See
ISRIsrael Kavkazi Jews0.00042840See
POLPoland DKMS0.000320653See
DEUGermany DKMS - Netherlands minority0.00041374See
USAUSA NMDP Southeast Asian0.000327978See
USAUSA NMDP Vietnamese0.000343540See
USAUSA NMDP South Asian Indian0.0002185391See
USAUSA Asian pop 20.00031772See
DEUGermany DKMS - Croatia minority0.00022057See
USAUSA NMDP Filipino0.000250614See
INDIndia North UCBB0.00.00025849See
INDIndia Central UCBB0.00.00014204See
USAUSA NMDP Chinese0.000199672See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
CHNChina Hubei Han0.00.00013732See
INDIndia West UCBB0.00.00015829See
INDIndia South UCBB0.00.000011446See
USAUSA NMDP Japanese0.000024582See
ISRIsrael Libya Jews0.00003739See
USAUSA NMDP Korean0.000077584See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
SGPSingapore SGVP Malay MAS0.000089See
SGPSingapore Chinese0.00.0000149See
SGPSingapore SGVP Chinese CHS0.000096See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA Caucasian Bethesda0.00.0000307See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
MEXMexico Mestizo0.00.000041See
MARMorocco Nador Metalsa pop 20.000073See
KORSouth Korea pop 30.0000485See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PRTPortugal Center0.000050See
PRTPortugal South0.000049See
PAKPakistan Baloch0.000066See
PHLPhilippines Ivatan0.00.000050See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
SCOScotland Orkney0.00.000099See
TURTurkey pop 50.0000142See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
HKGHong Kong Chinese0.00.0000569See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
BFABurkina Faso Fulani0.000049See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina Inner Mongolia Region0.0000102See
CUBCuba Caucasian0.00.000070See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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