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Population: 
   

  

United Arab Emirates Pop 1

Polymorphic Region:
HLA

Demographic Data

 
  Ethnic origin: Arab
  Geographic Region: Western Asia
  Latitude: 24º 42' N
  Longitude: 54º 82' E
  Family: Parents live at same location
  Urban/Rural: Urban and Rural

Sample Data

 
  Sample Size: 570
  Test date: 2024
  Method(s): NGS
  Source: Other
  Loci typed: A, B, C, DPA1, DPB1, DQA1, DQB1, DRB1, DRB3, DRB4, E, F, G
  Additional notes: If the outputs of xHLA and HLA-LA did not match, the following workflow was followed, as described in the publication: In summary, bioinformatics tools (xHLA and HLA-LA) were benchmarked and validated against gold standard targeted sequencing (i.e. O
 

Bibliographic Reference

 
  Author(s): Nour al dain Marzouka & Halima Alnaqbi et al
  Publication details: Marzouka, N. al dain, Alnaqbi, H., Al-Aamri, A., Tay, G. & Alsafar, H. Investigating the genetic makeup of the major histocompatibility complex (MHC) in the United Arab Emirates population through next-generation sequencing. Sci Rep 14, 3392 (2024). https://www.nature.com/articles/s41598-024-53986-1
  Author's e-mail: habiba.alsafar@ku.ac.ae
 

Frequency Data

 
Allele Frequencies Haplotype Frequencies 
 




   

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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