Allele Frequencies in World Populations

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The Allele Frequency Net Database is a free resource, we therefore welcome all kind of feedback. We envisage that this will benefit the research and medical community. If you have a comment, suggestion or query please send an e-mail to one of the following addresses:



Derek Middleton DSc, PhD, FRCPath
Transplant Immunology
Royal Liverpool University Hospital
Liverpool, L7 8XP
United Kingdom
Bioinformatics Staff
(General website queries)



Whilst AFND cannot assess the typing accuracy of data provided, >75% of the data on the website has been peer-reviewed and published. Thus, the AFND relies on the accuracy of data being verified by the reviewers of the journals and acts mainly as a source for compiling data. It is our intention in the future to collect the raw data in order that we can be more proactive in assessing the quality of data. Click here to consult a set of validations that are performed by our team.


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Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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