The KIR and Diseases Database (KDDB)

Introduction

The KIR and Diseases Database (KDDB) is also a section of the Allele Frequencies Net Database (AFND). The aim of this module is to provide users with an open source database listing known disease interactions between killer-cell immunoglobulin-like receptors (KIR) variants. Many infectious and autoimmune diseases have been associated with KIR genes in different ways, e.g. associations with single genes (or single alleles) to associations with groups of genes and full genotypes. As KIR disease association studies are in its infancy compared with HLA, we decided to start collecting KIR disease associations, as a new module within AFND.

The success of this module depends on your contribution. Please contact us if you have data to contribute.

Please cite this website using the following reference: Takeshita LY, Gonzalez-Galarza FF, dos Santos EJ, Maia MH, Rahman MM, Zain SM, Middleton D, Jones AR. A database for curating the associations between killer-cell immunoglobulin-like receptors and diseases in worldwide populations. Database (2013). doi: 10.1093/database/bat021 [Full text]

Database Information	Total
Published Studies	274
Countries	50
Disease Association Records	1474

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