Below are some frequently asked questions. Try to read these before you ask a new query.
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The Allele Frequency Net Database (AFND) is a public database which contains frequency information of several immune genes such as
Human Leukocyte Antigens (HLA), Killer-cell Immunoglobulin-like Receptors (KIR), Major histocompatibility complex class I chain-related (MIC) genes, and a
number of cytokine gene polymorphisms.
The AFND contains information at allele, haplotype and genotype level depending on the polymorphism. Users can navigate
in a number of different options to search population frequencies. There are also some other tools that can be useful for the community.
Please select one of the options from the left menu on the home page.
For each searching tool you will find a set of instructions to perform a particular query. A complete list of all available searches can be found
on the Site Map.
If you have a population study that has not been entered on the Allele Frequency Net Database you can
submit your data by entering the demographic information in the submission section. After entering your
demographic data you will receive a spreadsheet to enter the corresponding frequencies.
We have developed this website as a system that can run in any browser and any platform. However, for a best
performance please click here to check browser compatibilities and system recommendations.
Allele frequency net 2015 update:
new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and
Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.