Allele Frequencies in World Populations

Accessing AFND from external websites


Users can link the different searches available on the website from external sites by using a reference code (i.e., hla_selection, hla_locus, hla_allele, etc).

To include additional criteria in the same query, users can simply add an ampersand (&) to the link and the additional criteria. E.g. hla_region=Asia Note: If you are using this facility please cite our database in your website.


HLA SEARCHES

HLA Allele Frequency Search (hla6006a.asp)

Reference Code Description Value(s) Example
hla_locusLocus name{A, B, C, DRB1, ...}hla6006a.asp?hla_locus=A
hla_allele1Starting alleleA*01:01hla6006a.asp?hla_allele1=A*01:01
hla_allele2Ending allele (needs a starting allele)A*01:02hla6006a.asp?hla_allele1=A*01:01&hla_allele2=A*01:02
hla_selectionSelection of specific allelesA*01:01,A*01:02,A*02:01
(use commas to separate alleles)
hla6006a.asp?hla_selection=A*01:01,A*01:02,A*02:01
hla_countryCountry name{Albania, Argelia, American Samoa, ...}hla6006a.asp?hla_country=Albania
hla_regionGeographic Region{Asia, Australia, Eastern Europe, ...}hla6006a.asp?hla_region=Asia
hla_ethnicEthnic Origin{Amerindian, Black, Caucasian, ...}hla6006a.asp?hla_ethnic=Amerindian
hla_studyType of study{Anthropology, Blood Donor, Bone Marrow Registry, ...}hla6006a.asp?hla_study=Anthropology Study
hla_datasetSource of data{Literature, Proceedings of IHWs, Unpublished}hla6006a.asp?hla_dataset=Literature
hla_orderSort by{order_1=Allele, order_2=Allele and highest to lowest frequency, order_3=Population, order_4=Population and highest to lowest frequency}hla6006a.asp?hla_selection=A*01:01&hla_order=order_2

HLA Haplotype Frequency Search (hla6003a.asp)

Reference Code Description Value(s) Example
hla_selectionHaplotype{Allele_1-Allele_2-Allele_n}
e.g. A*01-B*08
hla6003a.asp?hla_selection=A*01-B*08
hla_countryCountry name{Albania, Argelia, American Samoa, ...}hla6003a.asp?hla_country=Albania
hla_regionGeographic Region{Asia, Australia, Eastern Europe, ...}hla6003a.asp?hla_region=Asia
hla_ethnicEthnic Origin{Amerindian, Black, Caucasian, ...}hla6003a.asp?hla_ethnic=Amerindian
hla_studyType of study{Anthropology, Blood Donor, Bone Marrow Registry, ...}hla6003a.asp?hla_study=Anthropology Study
hla_datasetSource of data{Literature, Proceedings of IHWs, Unpublished}hla6003a.asp?hla_dataset=Literature
hla_orderSort by{order_1=Haplotype, order_2=Population name, order_3=Highest to lowest frequency}hla6003a.asp?hla_selection=A*01-B*08&hla_order=order_3

HLA Rare Alleles Search (hla6001a.asp)

Reference Code Description Value(s) Example
all_nameAllele nameA*01:01:01:01hla6001a.asp?all_name=A*01:01:01:01


KIR SEARCHES

KIR Allele/Gene Frequency Search (kir6002a.asp)

Reference Code Description Value(s) Example
kir_locusLocus name{2DL1, 2DL2, 2DL3, ...}kir6002a.asp?kir_locus=2DL1
kir_allele1Starting allele2DL1*001kir6002a.asp?kir_allele1=2DL1*001
kir_allele2Ending allele (needs a starting allele)2DL1*002kir6002a.asp?kir_allele1=2DL1*001&kir_allele2=2DL1*002
kir_selectionSelection of specific alleles2DL1*001,2DL1*002,2DL1*003 (use commas to separate alleles)kir6002a.asp?kir_selection=2DL1*001,2DL1*002,2DL1*003
kir_countryCountry name{Albania, Argelia, American Samoa, ...}kir6002a.asp?kir_country=Argentina
kir_regionGeographic Region{Asia, Australia, Eastern Europe, ...}kir6002a.asp?kir_region=Asia
kir_ethnicEthnic Origin{Amerindian, Black, Caucasian, ...}kir6002a.asp?kir_ethnic=Amerindian
kir_studyType of study{Anthropology, Blood Donor, Bone Marrow Registry, ...}kir6002a.asp?kir_study=Anthropology Study
kir_datasetSource of data{Literature, Proceedings of IHWs, Unpublished}kir6002a.asp?kir_dataset=Literature
kir_orderSort by{order_1=Allele, order_2=Allele and highest to lowest frequency, order_3=Population, order_4=Population and highest to lowest frequency}kir6002a.asp?kir_selection=2DL1*001&kir_order=order_2

KIR Genotype Frequency Search (kir6001a.asp)

Reference Code Description Value(s) Example
kgen_groupHaplotype group{AA, Bx}kir6001a.asp?kgen_group=AA
kgen_countryCountry name{Albania, Argelia, American Samoa, ...}kir6001a.asp?kgen_country=Argentina
kgen_regionGeographic Region{Asia, Australia, Eastern Europe, ...}kir6001a.asp?kgen_region=Asia
kgen_ethnicEthnic Origin{Amerindian, Black, Caucasian, ...}kir6001a.asp?kgen_ethnic=Amerindian
kgen_studyType of study{Anthropology, Blood Donor, Bone Marrow Registry, ...}kir6001a.asp?kgen_study=Anthropology Study
kgen_datasetSource of data{Literature, Proceedings of IHWs, Unpublished}kir6001a.asp?kgen_dataset=Literature
kgen_orderSort by{order_1=Haplotype group and gene, order_2=Genotype ID, order_3=Number of Populations, order_4=Individuals}kir6001a.asp?kgen_country=Argentina&kgen_order=order_4


CYTOKINE SEARCHES

Cytokine Frequency Search (cyt6001a.asp)

Reference Code Description Value(s) Example
cyt_geneGene name{AIF-1/, bFGF/, EGF/, ...}cyt6001a.asp?cyt_gene=AIF-1/
cyt_allele1Starting cytokineAIF-1/ -932 CCcyt6001a.asp?cyt_allele1=AIF-1/ -932 CC
cyt_allele2Ending cytokine (needs a starting cytokine)AIF-1/ -932 TTcyt6001a.asp?cyt_allele1=AIF-1/ -932 CC&cyt_allele2=AIF-1/ -932 TT
cyt_selectionSelection of specific cytokinesAIF-1/ -932 CC,AIF-1/ -932 CT,AIF-1/ -932 TT
(use commas to separate alleles)
cyt6001a.asp?cyt_selection=AIF-1/ -932 CC,AIF-1/ -932 CT,AIF-1/ -932 TT
cyt_countryCountry name{Albania, Argelia, American Samoa, ...}cyt6001a.asp?cyt_country=Argentina
cyt_regionGeographic Region{Asia, Australia, Eastern Europe, ...}cyt6001a.asp?cyt_region=Asia
cyt_ethnicEthnic Origin{Amerindian, Black, Caucasian, ...}cyt6001a.asp?cyt_ethnic=Amerindian
cyt_studyType of study{Anthropology, Blood Donor, Bone Marrow Registry, ...}cyt6001a.asp?cyt_study=Anthropology Study
cyt_datasetSource of data{Literature, Proceedings of IHWs, Unpublished}cyt6001a.asp?cyt_dataset=Literature
cyt_orderSort by{order_1=Gene order, order_2=Population name, order_3=Frequency}cyt6001a.asp?cyt_selection=AIF-1/ -932 CC&cyt_order=order_3


MIC SEARCHES

MIC Frequency Search (mic6001a.asp)

Reference Code Description Value(s) Example
mic_locusLocus name{MICA, MICB}mic6001a.asp?mic_locus=MICA
mic_allele1Starting alleleMICA*001mic6001a.asp?mic_allele1=MICA*001
mic_allele2Ending allele (needs a starting allele)MICA*002mic6001a.asp?mic_allele1=MICA*001&mic_allele2=MICA*002
mic_selectionSelection of specific cytokinesMICA*001,MICA*002,MICA*003 (use commas to separate alleles)mic6001a.asp?mic_selection=MICA*001,MICA*002,MICA*003
mic_countryCountry name{Albania, Argelia, American Samoa, ...}mic6001a.asp?mic_country=Argentina
mic_regionGeographic Region{Asia, Australia, Eastern Europe, ...}mic6001a.asp?mic_region=Asia
mic_ethnicEthnic Origin{Amerindian, Black, Caucasian, ...}mic6001a.asp?mic_ethnic=Amerindian
mic_studyType of study{Anthropology, Blood Donor, Bone Marrow Registry, ...}mic6001a.asp?mic_study=Anthropology Study
mic_datasetSource of data{Literature, Proceedings of IHWs, Unpublished}mic6001a.asp?mic_dataset=Literature
mic_orderSort by{order_1=Allele/Gene, order_2=Allele/Gene and highest to lowest frequency, order_3=Population name, order_4=Population highest to lowest frequency}mic6001a.asp?mic_selection=MICA*001&mic_order=order_2

MIC Associations Frequency Search (mic6003a.asp)

Reference Code Description Value(s) Example
mic_selectionAssociationMICA*001-B*08mic6003a.asp?mic_selection=MICA*001-B*08
mic_countryCountry name{Albania, Argelia, American Samoa, ...}mic6003a.asp?mic_country=Argentina
mic_regionGeographic Region{Asia, Australia, Eastern Europe, ...}mic6003a.asp?mic_region=Asia
mic_ethnicEthnic Origin{Amerindian, Black, Caucasian, ...}mic6003a.asp?mic_ethnic=Amerindian
mic_studyType of study{Anthropology, Blood Donor, Bone Marrow Registry, ...}mic6003a.asp?mic_study=Anthropology Study
mic_datasetSource of data{Literature, Proceedings of IHWs, Unpublished}mic6003a.asp?mic_dataset=Literature
mic_orderSort by{order_1=Haplotype, order_2=Population name, order_3=Highest to lowest frequency}mic6003a.asp?mic_selection=A*01-B*08&mic_order=order_3





Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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