Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 41 time(s) and present in 39 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHLChile Easter Island0.095021See
ESPSpain, Canary Islands, Gran canaria island13.50.0721215See
ZAFSouth African Black12.70.0634142See
ZAFSouth Africa Caucasians0.0600102See
BRABrazil Rio de Janeiro Caucasian0.0537521See
CHLChile Huilliche NA-DHS_14 (G)10.00.050020See
BRABrazil Rio de Janeiro Parda0.0500170See
USAUSA San Francisco Caucasian0.0480220See
BRABrazil Barra Mansa Rio State Black0.047973See
BRABrazil Barra Mansa Rio State Caucasian0.0469405See
CRICosta Rica Guanacaste Mestizo (G)8.30.0460110See
BRABrazil Rio de Janeiro Black0.044168See
MARMorocco Nador Metalsa pop 20.041073See
ZAFSouth African Mixed ancestry8.00.040050See
USAUSA African American pop 30.0380564See
CRICosta Rica Amerindians (G)7.20.0360125See
USAUSA Mexican American Mestizo0.0340553See
COLColombia Inga NA-DHS_11 (G)6.70.033316See
ENGEngland North West6.40.0320298See
USAUSA Italy Ancestry0.0310273See
ENGEngland Blood Donors of Mixed Ethnicity6.00.0308519See
CRICosta Rica Central Valley Mestizo (G)5.80.0290221See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
CRICosta Rica African -Caribbean (G)5.00.0250102See
BOLBolivia/Peru Quechua NA-DHS_12 (G)4.80.023821See
POLPoland BMR2.70.013723595See
NICNicaragua Mestizo (G)2.60.0130155See
RUSRussia Belgorod region2.00.0098153See
SAUSaudi Arabia pop 6 (G)0.009728927See
RUSRussian Federation Vologda Region1.70.0084119See
CHNChina Qinghai Province Hui0.0050110See
GRCGreece Athens0.80.00421888See
USAUSA Spain Ancestry0.0040279See
INDIndia Kerala Malayalam speaking0.30.0010356See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.10.00065266See
USAUSA Arizona Gila River Pima0.00053000See
RUSRussia Nizhny Novgorod, Russians0.10.00031510See
CHNChina Zhejiang Han0.00031734See
CHNChina Inner Mongolia Region0.0000102See
CHNChina North Han0.0000105See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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