Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 25 time(s) and present in 25 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ZAFSouth African Black12.70.0775142See
CRICosta Rica African -Caribbean (G)12.80.0640102See
MARMorocco Settat Chaouya9.40.047098See
MARMorocco Atlantic Coast Chaouya0.047098See
BRABrazil Barra Mansa Rio State Black0.041173See
ZAFSouth African Mixed ancestry8.00.040050See
CRICosta Rica Guanacaste Mestizo (G)6.40.0320110See
BRABrazil Barra Mansa Rio State Caucasian0.0259405See
BRABrazil Rio de Janeiro Caucasian0.0240521See
CHLChile Easter Island0.024021See
NICNicaragua Mestizo (G)4.60.0230155See
ESPSpain, Canary Islands, Gran canaria island3.70.0209215See
BRABrazil Rio de Janeiro Parda0.0206170See
ZAFSouth African Indian population4.00.020050See
SAUSaudi Arabia pop 6 (G)0.016628927See
CRICosta Rica Amerindians (G)3.20.0160125See
USAUSA San Francisco Caucasian0.0160220See
CRICosta Rica Central Valley Mestizo (G)2.80.0140221See
ENGEngland Blood Donors of Mixed Ethnicity1.70.0087519See
BRABrazil Rio de Janeiro Black0.007468See
RUSRussia Belgorod region1.30.0065153See
POLPoland BMR1.00.005023595See
GRCGreece Athens0.80.00421888See
RUSRussian Federation Vologda Region0.80.0042119See
USAUSA Arizona Gila River Pima0.00063000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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