Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 30 time(s) and present in 29 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
RUSRussia Bashkortostan, Tatars4.70.0234192See
USAUSA Spain Ancestry0.0220279See
USAUSA Italy Ancestry0.0220273See
GRCGreece Athens4.30.02171888See
RUSRussian Federation Vologda Region4.20.0210119See
USAUSA Mexican American Mestizo0.0180553See
MEXMexico Hidalgo Mezquital Valley/ Otomi1.40.013972See
BRABrazil Barra Mansa Rio State Black0.013773See
BRABrazil Barra Mansa Rio State Caucasian0.0136405See
BRABrazil Rio de Janeiro Caucasian0.0134521See
LBYLibya Cyrenaica0.0130118See
POLPoland BMR2.30.011623595See
USAUSA San Francisco Caucasian0.0110220See
SAUSaudi Arabia pop 6 (G)0.010828927See
RUSRussia Nizhny Novgorod, Russians2.10.01061510See
ZAFSouth African Mixed ancestry2.00.010050See
RUSRussia Belgorod region2.00.0098153See
CRICosta Rica Guanacaste Mestizo (G)1.80.0090110See
BRABrazil Rio de Janeiro Parda0.0088170See
BRABrazil Rio de Janeiro Black0.007568See
CRICosta Rica Central Valley Mestizo (G)1.40.0070221See
ESPSpain, Canary Islands, Gran canaria island1.40.0069215See
SAUSaudi Arabia pop 50.60.0032158See
IDNIndonesia Sundanese and Javanese0.0030201See
ENGEngland North West0.70.0030298See
ENGEngland Blood Donors of Mixed Ethnicity0.40.0019519See
CHNChina Zhejiang Han0.00121734See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.10.00045266See
USAUSA Arizona Gila River Pima0.00023000See
IDNIndonesia Java pop 20.000036See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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