Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 46 time(s) and present in 46 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0690146See
RUSRussia Belgorod region10.50.0556153See
GTMGuatemala Kaqchikel NA-DHS_8 (G)10.50.052619See
GEOGeorgia Tibilisi0.0460109See
RUSRussia Bashkortostan, Bashkirs8.30.0417120See
USAUSA New Mexico Canoncito Navajo0.037042See
COLColombia Inga NA-DHS_11 (G)7.10.035716See
POLPoland BMR6.90.035623595See
RUSRussia Nizhny Novgorod, Russians6.50.03341510See
RUSRussian Federation Vologda Region5.90.0294119See
CRICosta Rica Amerindians (G)5.80.0290125See
MEXMexico Mixtec NA-DHS_5 (G)5.00.025020See
ISRIsrael Arab Druze0.0250101See
USAUSA Mexican American Mestizo0.0240553See
BRABrazil Rio de Janeiro Caucasian0.0230521See
GRCGreece Athens4.60.02281888See
BRABrazil Rio de Janeiro Black0.022468See
BRABrazil Mixed0.0220108See
USAUSA Italy Ancestry0.0220273See
USAUSA San Francisco Caucasian0.0210220See
BRABrazil Barra Mansa Rio State Caucasian0.0210405See
BRABrazil Rio de Janeiro Parda0.0206170See
CANCanada Chipewyan NA-DHS_2 (G)4.00.020025See
CRICosta Rica Central Valley Mestizo (G)4.00.0200221See
NICNicaragua Mestizo (G)3.20.0190155See
ESPSpain, Canary Islands, Gran canaria island3.70.0186215See
GEOGeorgia Tibilisi Kurd0.017031See
LBYLibya Cyrenaica0.0170118See
RUSRussia Bashkortostan, Tatars3.10.0156192See
CRICosta Rica Guanacaste Mestizo (G)2.80.0140110See
CHNChina South Han0.0120284See
ENGEngland North West2.00.0100298See
ASMAmerican Samoa0.010051See
ZAFSouth African Indian population2.00.010050See
ZAFSouth African Mixed ancestry2.00.010050See
SAUSaudi Arabia pop 51.90.0095158See
ENGEngland Blood Donors of Mixed Ethnicity1.70.0087519See
BRABrazil Barra Mansa Rio State Black0.006873See
SGPSingapore Chinese Han0.006094See
HKGHong Kong Chinese HKBMDR HLA 11 loci1.10.00555266See
SGPSingapore Riau Malay0.0050132See
USAUSA Spain Ancestry0.0050279See
INDIndia Karnataka Kannada Speaking0.60.0030174See
CHNChina Zhejiang Han0.00141734See
USAUSA Arizona Gila River Pima0.00023000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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