Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 31 time(s) and present in 26 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA Arizona Gila River Pima0.07933000See
MEXMexico Mixtec NA-DHS_5 (G)10.00.050020See
USAUSA Mexican American Mestizo0.0300553See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
MEXMexico Guadalajara Mestizo pop 20.0190103See
NICNicaragua Mestizo (G)2.60.0130155See
MEXMexico Chihuahua Tarahumara0.011044See
ZAFSouth African Mixed ancestry2.00.010050See
IRNIran Baloch0.0100100See
BRABrazil Rio de Janeiro Parda0.0088170See
ENGEngland Blood Donors of Mixed Ethnicity1.70.0087519See
BRABrazil Barra Mansa Rio State Caucasian0.0074405See
MARMorocco Settat Chaouya1.40.007098See
USAUSA San Francisco Caucasian0.0070220See
MARMorocco Atlantic Coast Chaouya0.007098See
RUSRussia Belgorod region1.30.0065153See
USAUSA African American pop 30.0040564See
POLPoland BMR0.70.003423595See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
ENGEngland North West0.30.0020298See
BRABrazil Rio de Janeiro Caucasian0.0019521See
INDIndia Kerala Malayalam speaking0.30.0010356See
RUSRussia Nizhny Novgorod, Russians0.20.00101510See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.00.00015266See
MARMorocco Nador Metalsa pop 20.000073See
KORSouth Korea pop 30.0000485See
CHNChina North Han0.0000105See
CZECzech Republic0.0000106See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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