Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 30 time(s) and present in 27 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Zhejiang Han0.15971734See
HKGHong Kong Chinese HKBMDR HLA 11 loci28.50.15425266See
VNMVietnam Kinh15.00.0792101See
ENGEngland Blood Donors of Mixed Ethnicity10.60.0578519See
RUSRussian Federation Vologda Region7.60.0420119See
RUSRussia Nizhny Novgorod, Russians7.70.04041510See
ZAFSouth African Mixed ancestry8.00.040050See
RUSRussia Belgorod region7.80.0392153See
POLPoland BMR6.80.034623595See
ESPSpain, Canary Islands, Gran canaria island7.00.0326215See
ZAFSouth African Indian population6.00.030050See
BRABrazil Barra Mansa Rio State Caucasian0.0247405See
INDIndia Andhra Pradesh Telugu Speaking4.30.0242186See
USAUSA Arizona Gila River Pima0.02123000See
BRABrazil Rio de Janeiro Caucasian0.0192521See
RUSRussia Bashkortostan, Tatars3.10.0156192See
INDIndia Kerala Malayalam speaking3.10.0150356See
CHNChina Jingpo Minority2.90.0150105See
BRABrazil Rio de Janeiro Black0.014968See
BRABrazil Barra Mansa Rio State Black0.013773See
GRCGreece Athens2.50.01271888See
GRCGreece Athens2.50.01271888See
GRCGreece Athens2.50.01271888See
GRCGreece Athens2.50.01271888See
RUSRussia Bashkortostan, Bashkirs2.50.0125120See
BRABrazil Rio de Janeiro Parda0.0118170See
ZAFSouth African Black0.70.0035142See
KORSouth Korea pop 30.0000485See
MARMorocco Nador Metalsa pop 20.000073See
CHNChina North Han0.0000105See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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