Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 131 time(s) and present in 83 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Libya Jews0.10223739See
USAUSA Spain Ancestry0.0480279See
MARMorocco Nador Metalsa pop 20.043073See
LBYLibya Cyrenaica0.0170118See
TUNTunisia Gabes0.015795See
MARMorocco Settat Chaouya2.80.014098See
MARMorocco Atlantic Coast Chaouya0.014098See
PRTPortugal North0.011046See
PRTPortugal South0.010049See
IRNIran Yazd0.008956See
ESPSpain, Canary Islands, Gran canaria island1.40.0069215See
TUNTunisia pop 30.0060104See
BRABrazil Rio de Janeiro Caucasian0.0058521See
CHESwitzerland Sion0.0049832See
DEUGermany DKMS - Portugal minority0.00471176See
CHESwitzerland Luzern0.00421553See
CHESwitzerland Graubunden0.0041759See
AUSAustralia New South Wales Caucasian0.0040134See
USAUSA South Texas Hispanic0.0040194See
USAUSA Caucasian Bethesda0.80.0040307See
BRABrazil Barra Mansa Rio State Caucasian0.0037405See
CHESwitzerland Basel0.00351888See
NICNicaragua Mestizo (G)0.60.0030155See
JORJordan Amman0.0030146See
ISRIsrael Morocco Jews0.002736718See
CHESwitzerland Bern0.00263545See
USAUSA NMDP Mexican or Chicano0.0024261235See
DEUGermany DKMS - Spain minority0.00231107See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.40.00224335See
ENGEngland North West0.30.0020298See
USAUSA Italy Ancestry0.0020273See
USAUSA Mexican American Mestizo0.0020553See
ZWEZimbabwe Harare Shona0.0020230See
USAUSA NMDP Hispanic South or Central American0.0020146714See
ISRIsrael Tunisia Jews0.00189070See
USAUSA NMDP Caribean Hispanic0.0017115374See
DEUGermany DKMS - Italy minority0.00171159See
NICNicaragua Managua0.30.0015339See
DEUGermany DKMS - France minority0.00111406See
ITAItaly pop 50.0010975See
USAUSA NMDP Caribean Indian0.001014339See
USAUSA NMDP American Indian South or Central America0.00105926See
USAUSA Hispanic pop 20.00101999See
USAUSA Eastern European0.0010558See
USAUSA Caucasian pop 40.00091070See
USAUSA NMDP Hawaiian or other Pacific Islander0.000811499See
COLColombia Bogotá Cord Blood0.10.00071463See
RUSRussia Nizhny Novgorod, Russians0.10.00071510See
USAUSA Caucasian0.10.000561655See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000470890See
USAUSA NMDP European Caucasian0.00041242890See
ISRIsrael Arab pop 20.000412301See
USAUSA NMDP North American Amerindian0.000435791See
CZECzech Republic NMDR0.00035099See
DEUGermany DKMS - Austria minority0.00031698See
DEUGermany DKMS - Netherlands minority0.00041374See
SAUSaudi Arabia pop 6 (G)0.000328927See
DEUGermany DKMS - German donors0.00033456066See
ISRIsrael Ashkenazi Jews pop 30.00024625See
DEUGermany pop 80.000239689See
DEUGermany DKMS - Croatia minority0.00022057See
USAUSA African American pop 40.00022411See
USAUSA NMDP Caribean Black0.000233328See
USAUSA NMDP African0.000228557See
ISRIsrael Iraq Jews0.000213270See
ISRIsrael Argentina Jews0.00014307See
USAUSA NMDP African American pop 20.0001416581See
HRVCroatia pop 40.00014000See
DEUGermany DKMS - Turkey minority0.00014856See
DEUGermany pop 60.00028862See
USAUSA NMDP Filipino0.000150614See
USAUSA NMDP Japanese0.000124582See
ISRIsrael Poland Jews0.000113871See
ISRIsrael YemenJews0.000115542See
POLPoland BMR0.00.000123595See
ISRIsrael Iran Jews0.00018153See
ISRIsrael USSR Jews0.000045681See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Korean0.000077584See
USAUSA NMDP Chinese0.000099672See
USAUSA Philadelphia Caucasian0.00.0000141See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA Asian pop 20.00001772See
USAUSA African American Bethesda0.00.0000187See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
SDNSudan Mixed0.00.0000200See
SGPSingapore Chinese0.00.0000149See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
HKGHong Kong Chinese0.00.0000569See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
PRTPortugal Center0.000050See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PHLPhilippines Ivatan0.00.000050See
KORSouth Korea pop 30.0000485See
MEXMexico Mestizo0.00.000041See
CHESwitzerland St Gallen0.00002113See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Zurich0.00004875See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
AUSAustralia Yuendumu Aborigine0.0000191See
CHESwitzerland Aargau-Solothurn0.00001838See
BRABrazil Belo Horizonte Caucasian0.00.000095See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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