Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 397 time(s) and present in 339 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
TURTurkey pop 20.0710228See
IRNIran pop 10.070064See
TWNTaiwan Aborigine0.0670111See
CHNChina Yunnan Province Naxi0.0670118See
LKASri Lanka Colombo Sinhalese0.0640101See
ESPSpain Majorcans Jews0.0600103See
MMRMyanmar Chin10.90.054555See
CHNChina Yunnan Province Han pop 20.0530129See
IRNIran pop 40.0515855See
INDIndia Kerala Kurichiya0.050010See
ITAItaly Sardinia pop30.0500100See
ARMArmenia Ghegharkunik0.0500242See
CHNChina Wuhan10.00.0500121See
MMRMyanmar Kachin7.90.047663See
MKDMacedonia pop 40.0460216See
THAThailand Northeast pop 20.0460400See
TUNTunisia Ghannouch0.043082See
PAKPakistan Brahui0.0430104See
MNGMongolia Tsaatan0.0420144See
BGDBangladesh Dhaka Bangalee0.0420141See
ITAItaly Bergamo6.90.0410101See
FRAFrance Rennes pop 30.0400200See
ESPSpain Catalonia Girona0.040088See
ARMArmenia Lori0.0390102See
GRCGreece Crete0.0370135See
THAThailand Northeast0.037066See
GEOGeorgia Kurds0.036030See
TWNTaiwan Minnan and Hakka0.0340190See
MEXMexico Morelos Rural0.033330See
DEUGermany Essen6.30.0330174See
MKDMacedonia MBMDR - Macedonian Muslims6.60.032976See
SCOScotland Orkney6.40.032099See
INDIndia Kerala Syrian Christian0.032031See
INDIndia Kerala Hindu Pulaya0.031016See
KURIraq Kurdistan Region5.70.0310209See
FRAFrance Southeast6.20.0310130See
TWNTaiwan Hakka pop 20.0310714See
GRCGreece pop36.10.0309246See
IRNIran Royan Cord Blood Bank6.00.030015600See
CHNChina Shanghai0.030026266See
TWNTaiwan Minnan pop 20.03007137See
ARMArmenia living in USA0.0300233See
ARMArmenia Syunik0.0300117See
BIHBosnia and Herzegovina0.0298134See
JPNJapan pop 20.0280916See
ESPSpain Majorca and Minorca0.028090See
ENGEngland Lancaster5.50.0278545See
MARMorocco Casablanca0.0270100See
NORNorway Sami0.0270200See
GRCGreece North0.0270500See
SVNSlovenia pop 35.40.0270130See
GRCGreece pop 70.026411250See
ARGArgentina Salta Wichi pop 25.30.026019See
MKDMacedonia pop 30.0260172See
JPNJapan Hyogo Osaka and Nagano0.0260195See
ALBAlbania pop 25.10.0255432See
MEXMexico Sonora, Hermosillo0.025399See
ARMArmenia living in Karabakh0.0250445See
CHNChina Jiangsu Province0.025020248See
MNGMongolia Khalkha0.0250200See
CHNChina Harbin Manchu0.0250172See
FRAFrance Reims0.0250102See
FRAFrance Corsica Island0.0250100See
ENGEngland London Ashkenazi Jews0.0250500See
ENGEngland Liverpool4.80.02431343See
JPNJapan pop 114.80.024362See
INDIndia Kerala Hindu Nair0.024041See
CHNChina Guangzhou Han0.0240106See
ARMArmenia living in Iran0.024085See
GBRUnited Kingdom Orkney0.024088See
MKDMacedonia MBMDR - Albanian4.70.0234128See
BRABrazil Parana Japanese5.00.0234192See
TWNTaiwan Chinese immigrants from South China0.0230172See
MKDMacedonia MBMDR - Macedonian4.50.02301283See
BRABrazil Curitiba-Parana Mixed0.0226264See
ISRIsrael Moroccan Jews0.0220113See
ARMArmenia Yerevan0.0220445See
THAThailand pop 40.022016807See
FRAFrance Rennes pop 44.40.02181000See
ENGEngland Newcastle4.20.02122739See
TWNTaiwan Chinese immigrants from Middle China0.0210211See
HRVCroatia pop 34.20.0208120See
ROMRomania pop 34.20.02081469See
MEXMexico Nayarit, Tepic0.020697See
CZECzech Republic Kurd4.10.020374See
IRQIraq Erbil4.00.0202372See
IRLIreland South pop 20.020117624See
USAUSA OPTN Asian0.0200261See
ITAItaly Rome4.00.0200100See
CHNChina Shaanxi Province Han0.020010000See
CHNChina Harbin Korean0.0200201See
MYSMalaysia Perak Rawa0.020023See
ROMRomania pop 20.02006936See
WALWales pop 23.90.020039979See
INDIndia North Gujarat3.90.0192338See
ITAItaly Lombardy3.70.0190674See
ISRIsrael Jews pop 23.80.019023000See
MNGMongolia Oold0.0190104See
ITAItaly North Pavia pop 30.0189685See
ENGEngland Manchester3.70.01861640See
CHNChina Guangdong Province3.70.0186403See
CHNChina Shandong Province Linqu County3.60.0181139See
USAUSA OPTN Caucasian0.01808525See
TURTurkey pop 50.0180142See
FRAFrance Grenoble, Nantes and Rennes0.01806094See
CHNChina Shandong Province3.50.01807418See
GBRUnited Kingdom renal patients3.60.01807007See
MEXMexico Nuevo Leon, Monterrey city0.0177226See
ENGEngland Leeds3.50.01765024See
FRAFrance Lyon3.50.01744813See
MEXMexico San Luis Potosi Rural0.017287See
ARGArgentina Cuyo Region3.30.0170420See
JPNJapan Tohoku Region0.0170322See
ITAItaly North Pavia pop 23.40.01702416See
FRAFrance Marseille3.30.01641000See
ENGEngland Sheffield3.20.01614755See
INDIndia North pop 30.0160587See
KORSouth Korea pop 80.01607096See
ARGArgentina Buenos Aires3.20.0160466See
USAUSA Caucasian Bethesda3.20.0160307See
JPNJapan Hyogo3.10.016032See
ARGArgentina Corrientes3.20.0160155See
MEXMexico Veracruz, Xalapa0.0160187See
MEXMexico Jalisco, Guadalajara city0.01591189See
SVKSlovakia pop 20.01564234See
GBRUnited Kingdom East0.0155163See
MEXMexico Yucatan, Merida0.0154192See
ITAItaly South Campania Region3.00.01511089See
BRABrazil Parana Oriental3.00.015033See
MNGMongolia Khalkha pop 20.0150202See
PRTPortugal Bragança0.0150301See
GBRUnited Kingdom pop 20.0150101See
HRVCroatia pop 20.0150100See
GAZGaza Palestinians0.0150165See
ARMArmenia living in Lebanon0.0150368See
SWESweden pop 43.00.0150966See
MEXMexico Mayan Pop 30.015066See
SRBSerbia Vojvodina3.00.0150400See
MEXMexico Baja Californa, Mexicali0.0150100See
MEXMexico Nuevo Leon Rural0.0148439See
FRAFrance Bordeaux2.90.0146990See
PRTPortugal Beja0.0140699See
PRTPortugal Evora0.0140737See
PRTPortugal Guarda0.0140797See
PRTPortugal Porto0.01407937See
KORSouth Korea pop 10.0140324See
ESPSpain Majorca0.0140407See
AUSAustralia West Caucasian2.70.0140891See
PAKPakistan Kalash0.014069See
FRAFrance Grenoble2.80.01391000See
BRABrazil REDOME Rio Grande do Sul0.0137241329See
BRABrazil REDOME Santa Catarina0.0136106673See
ITAItaly pop 62.70.0136184See
CHLChile Santiago0.0136920See
SWESweden Uppsala2.70.0135300See
BRABrazil REDOME Sergipe0.01337321See
MEXMexico Baja California, La Paz0.013375See
ARMArmenia Shirak0.013076See
ESPSpain North Cabuerniga0.013095See
ESPSpain Arratia Valley Basque0.013083See
TWNTaiwan Chinese immigrants from North China0.0130152See
PRTMadeira pop 30.0130538See
PRTPortugal Faro0.01301242See
BRABrazil Minas Gerais State Mixed2.40.01301000See
MEXMexico Jalisco, Tlaquepaque0.012839See
RUSRussia Tatars0.0126355See
GBRUnited Kingdom North0.0123330See
MEXMexico Hidalgo, Pachuca0.012241See
MEXMexico Durango Rural0.0122326See
BRABrazil REDOME Espirito Santo0.012088485See
JPNJapan Kyoto and Osaka0.0120165See
PRTPortugal Portalegre0.01201254See
PRTPortugal Setubal0.01205268See
MEXMexico Mexico City Mestizo0.0120121See
ITAItaly North Pavia0.012081See
BRABrazil REDOME Parana0.0118341639See
BRABrazil REDOME Pernambuco0.011892332See
BRABrazil South East Cord Bllod0.011711409See
NORNorway ethnic Norwegians2.30.01174510See
MEXMexico Queretaro Rural0.011643See
BRABrazil REDOME Sao Paulo0.0116800809See
BRABrazil REDOME Acre0.0116859See
SRBSerbia pop 32.30.01131992See
GBRUnited Kingdom Central0.0113135See
MEXMexico Veracruz, Poza Rica0.011145See
POLPoland pop 32.20.01112907See
BRABrazil Rio Grande do Sul Caucasoid0.01104428See
PRTPortugal North0.011046See
USAUSA OPTN Hispanic0.01101580See
ESPSpain Minorca0.011094See
ESPSpain Ibiza0.011088See
JPNJapan Aichi2.20.011050See
PRTPortugal Braga0.01101971See
PRTPortugal Vila Real0.01101167See
PRTPortugal Santarem0.01103865See
PRTPortugal Coimbra0.01105057See
PRTPortugal Lisbon0.011017420See
AREUnited Arab Emirates pop 22.10.0110373See
RUSRussia Northwest pop 22.10.0110346See
PRTPortugal South pop 20.01101021See
ARGArgentina Buenos Aires pop 22.20.01101216See
CZECzech Republic Gypsy pop 22.20.010946See
BRABrazil REDOME Rondonia0.010654396See
BRABrazil REDOME Mato Grosso0.010634649See
BRABrazil REDOME Federal District0.010429549See
MMRMyanmar Rakhine2.10.010448See
BRABrazil REDOME Tocantins0.010320692See
PRTPortugal North pop 20.01031801See
BRABrazil REDOME Piaui0.010246140See
BRABrazil REDOME Alagoas0.010225349See
ITAItaly East Sicily2.00.010050See
RUSRussia Murmansk Saomi Mixed0.010070See
PAKPakistan Mixed Pathan0.0100100See
PAKPakistan Burusho0.010092See
DZAAlgeria pop 22.00.0100106See
NORNorway pop 20.0100576See
PRTPortugal Viseu0.01002915See
PRTPortugal Viana do Castelo0.0100706See
BRABrazil Parana Caucasian1.90.01002775See
PRTPortugal Leiria0.01001847See
VNMVietnam Hanoi0.010050See
PRTPortugal Aveiro0.01005933See
RUSRussia Samara Region0.01002500See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.010096See
RUSRussia South Ural Bashkir2.10.0100146See
RUSRussia Moscow0.01002650See
BRABrazil Piaui Mixed0.010021943See
MEXMexico Michoacan, Morelia0.0099150See
MEXMexico Mexico City Metropolitan Area Rural0.0099150See
BRABrazil REDOME Bahia0.009647399See
RUSRussia Moscow Pop 21.90.00952000See
MEXMexico Zacatecas, Fresnillo0.0095103See
BRABrazil REDOME Goias0.009488574See
BRABrazil REDOME Mato Grosso do Sul0.009495667See
BRABrazil REDOME Para0.009372637See
BRABrazil REDOME Ceara0.0093101217See
MEXMexico Mestizo pop 40.0093269See
MEXMexico Chihuahua, Ciudad Juarez0.0093106See
MEXMexico Coahuila Rural0.0092216See
MEXMexico Guanajuato Rural0.0092162See
BRABrazil REDOME Rio de Janeiro0.0091139322See
ARGArgentina La Plata2.00.0090100See
BRABrazil Sao Paulo Bauru Mixed0.00903542See
CZECzech Republic0.0090106See
MEXMexico Sinaloa Mestizo0.009056See
MARMorocco pop 20.0090110See
MYSMalaysia pop 20.009062See
BRABrazil Parana Cafuzo1.90.0090319See
MYSMalaysia Sabah Kadazan0.009057See
MEXMexico Jalisco, Zapopan0.0089168See
MEXMexico Veracruz, Cordoba0.008956See
BRABrazil REDOME Amapa0.008817864See
BRABrazil REDOME Minas Gerais0.0085211275See
MEXMexico Chihuahua Rural0.0084236See
MEXMexico Veracruz, Orizaba0.008360See
BRABrazil REDOME Paraiba0.008343868See
BIHBosnia and Herzegovina pop 21.70.0083120See
ALBAlbanian Kosovo0.0083120See
MEXMexico Colima, Colima city0.008261See
BRABrazil South Ribeirao Preto0.0080184See
BRABrazil Parana Mulatto1.60.0080186See
RUSRussia Nenet Mixed0.008055See
BRABrazil REDOME Amazonas0.008024129See
MEXMexico Tamaulipas Rural0.0079125See
BRABrazil Paraná Caucasian1.60.0078641See
BRABrazil REDOME Rio Grande do Norte0.007846603See
BRABrazil REDOME Roraima0.00764140See
BRABrazil REDOME Maranhao0.007510180See
BOLBolivia Quechua0.007080See
PERPeru Arequipa Mestizo1.40.0070168See
MYSMalaysia pop 30.00701445See
RUSRussia South Ural Tatar1.50.0070135See
BRABrazil Rio Grande do Norte Mestizo0.007012973See
CUBCuba Mixed0.007078See
MEXMexico Michoacan Tarasco1.50.0070130See
RUSRussia Transbaikal Territory Buryats1.00.0070150See
MEXMexico Sonora, Ciudad Obregón0.0070143See
MEXMexico Coahuila, Saltillo0.006872See
ECUEcuador Andes Mixed Ancestry0.0067824See
MEXMexico Veracruz Rural0.0065539See
MEXMexico Hidalgo Rural0.006281See
MEXMexico Oaxaca Rural0.0062485See
MEXMexico Tabasco, Villahermosa0.006182See
MEXMexico Morelos, Cuernavaca0.006182See
ESPSpain North Cantabria0.006083See
RUSRussia Northwest1.20.00601011See
BRABrazil Rio Grande do Sul Black0.0060248See
SAUSaudi Arabia pop 41.20.0060499See
VENVenezuela Colonia Tovar0.005886See
MEXMexico Veracruz, Veracruz city0.0058171See
ECUEcuador Mixed Ancestry0.00551173See
MEXMexico Puebla, Puebla city0.00551994See
MEXMexico Tlaxcala, Tlaxcala city0.0055181See
ESPSpain Sevilla1.10.0054278See
ENGEngland North West Mixed pop 21.10.0053379See
MEXMexico Aguascalientes state0.005395See
MEXMexico Coahuila, Torreon0.0050396See
SAUSaudi Arabia pop 20.0050383See
ESPSpain Gipuzkoa Basque0.0050100See
RUSRussia Northwest pop 31.00.0050100See
RUSRussia South Ural Russian1.00.0050207See
USAUSA African American Bethesda1.10.0050187See
USAUSA OPTN African American0.00501510See
BRABrazil Pernambuco Mixed0.0050101See
MEXMexico Sinaloa, Culiacán0.0049103See
MEXMexico Michoacan Rural0.0043348See
MEXMexico Chiapas Rural0.0041121See
ISRIsrael Ashkenazi Jews pop 20.0040132See
PRTAzores Terceira Island0.0040130See
ESPSpain Murcia0.0040173See
BRABrazil Rio Grande do Sul Mixed0.0040324See
CUBCuba Mixed pop 20.0040189See
RUSRussia North Ossetian0.80.0039127See
MEXMexico Yucatan Rural0.0037132See
MEXMexico Guerrero state0.0035144See
MEXMexico Jalisco Rural0.0034585See
MEXMexico Oaxaca, Oaxaca city0.0033151See
MEXMexico Mexico City Center0.0032152See
GBRUnited Kingdom South West0.0032163See
PRTMadeira pop 20.0030173See
PRTPortugal Castelo Branco0.0030327See
COLColombia Barranquilla0.0030188See
MEXMexico Tlaxcala Rural0.0030830See
MEXMexico Sinaloa Rural0.0027183See
MEXMexico Sonora Rural0.0025197See
ECUEcuador Coast Mixed Ancestry0.0021238See
MEXMexico Puebla Rural0.0012833See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Campeche Rural0.000047See
MEXMexico Zacatecas Rural0.0000266See
MEXMexico Nayarit Rural0.000064See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Mexico City South0.000052See
MEXMexico Mexico City North0.0000751See
MEXMexico Mexico City East0.000079See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Colima Rural0.000043See
MEXMexico Baja California Rural0.000050See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Campeche, Campeche city0.000034See
ECUEcuador Amazonia Mixed Ancestry0.000039See
RUSRussia Arkhangelsk Pomor0.000063See
ZAFSouth Africa Natal Zulu0.00.0000100See
ARGArgentina Chiriguano0.00.000054See
BRABrazil Sao Paulo Mixed0.00.0000239See
ITAItaly North pop 30.00.000097See
VENVenezuela Caracas Mestizo0.000050See
PAKPakistan Baloch0.000066See
PAKPakistan Mixed Sindhi0.0000101See
MEXMexico Nahuas0.000072See
MEXMexico Huasteca Region Teenek0.000055See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.000094See
CHNChina North Han0.0000105See
BRABrazil Parana Afro Brazilian0.00.000077See
TZATanzania Dodoma Kongwa0.0000212See
MEXMexico Puebla Mestizo0.000099See
PAKPakistan Karachi Parsi0.000091See
SAUSaudi Arabia0.00.000018See
RUSRussia Sakhalin Island Nivkhi0.000053See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
INDIndia Kerala Hindu Ezhava0.000024See
INDIndia Kerala Malabar Muslim0.000034See
INDIndia Kerala Hindu Namboothiri0.000040See
INDIndia Kerala Paniya0.000010See
INDIndia Kerala Malapandaram0.000010See
INDIndia Kerala Adiya0.000021See
INDIndia Kerala Kanikkar0.000022See
INDIndia Kerala Kattunaikka0.000017See
INDIndia Kerala Kuruma0.000015See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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