Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 86 time(s) and present in 43 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MYSMalaysia Pahang Semai10.50.053038See
USAUSA NMDP Hawaiian or other Pacific Islander0.040611499See
MYSMalaysia Patani8.00.040025See
USAUSA NMDP Vietnamese0.011243540See
INDIndia West Coast Parsi0.010050See
TWNTaiwan Siraya2.00.010051See
ASMAmerican Samoa0.010051See
CHNChina Jingpo Minority1.90.0100105See
VNMVietnam Kinh2.00.0099101See
CHNChina Yunnan Province Lisu0.0070111See
SGPSingapore SGVP Malay MAS0.006089See
SGPSingapore Riau Malay0.0050132See
CHNChina Guangdong Province Meizhou Han0.0050100See
USAUSA NMDP Filipino0.004650614See
CHNChina South Han0.0040284See
CHNChina Guizhou Province Shui0.0040153See
TWNTaiwan Han Chinese0.0030504See
CHNChina Canton Han0.0020264See
CHNChina Marrow Donor Registry0.0020600See
HKGHong Kong Chinese BMDR0.00177595See
USAUSA NMDP Southeast Asian0.001627978See
USAUSA NMDP Chinese0.001499672See
INDIndia Tamil Nadu0.00142492See
USAUSA Asian pop 20.00141772See
HKGHong Kong Chinese0.20.0010569See
CHNChina Jiangsu Han0.00103238See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
CHNChina Zhejiang Han0.00091734See
HKGHong Kong Chinese cord blood registry0.00053892See
CHNChina Hubei Han0.10.00053732See
CHESwitzerland Geneva pop 20.00031267See
SAUSaudi Arabia pop 6 (G)0.000128927See
DEUGermany DKMS - Turkey minority0.00014856See
USAUSA NMDP South Asian Indian0.0001185391See
USAUSA NMDP Korean0.000177584See
ISRIsrael Libya Jews0.00003739See
USAUSA NMDP African American pop 20.0000416581See
ISRIsrael Bukhara Jews0.00002317See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000070890See
USAUSA NMDP Mexican or Chicano0.0000261235See
DEUGermany DKMS - German donors0.00003456066See
ISRIsrael Iran Jews0.00008153See
USAUSA NMDP Caribean Hispanic0.0000115374See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA Hispanic pop 20.00001999See
USAUSA African American pop 40.00002411See
SGPSingapore Chinese0.00.0000149See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
SGPSingapore SGVP Chinese CHS0.000096See
SGPSingapore SGVP. Indian INS0.000086See
THAThailand pop 30.000049See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHNChina Guizhou Province Miao pop 20.000085See
CHNChina Guizhou Province Bouyei0.0000109See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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