Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 82 time(s) and present in 48 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
ASMAmerican Samoa0.020051See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0160146See
CHNChina Yunnan Province Han0.0150101See
TWNTaiwan Siraya2.00.010051See
CHNChina Hubei Han1.60.00793732See
DEUGermany DKMS - China minority0.00741282See
CHNChina Guizhou Province Miao pop 20.006085See
RUSRussia Tuva pop 20.0060169See
CHNChina North Han pop 20.0053567See
CHNChina Guangdong Province Meizhou Han0.0050100See
TWNTaiwan pop 20.0050364See
JPNJapan pop 10.0050560See
TWNTaiwan Minnan pop 11.00.0050102See
BRABrazil Mixed0.0050108See
HKGHong Kong Chinese BMDR0.00467595See
JPNJapan Central0.0040371See
JPNJapan pop 30.00401018See
USAUSA South Texas Hispanic0.0040194See
CHNChina Zhejiang Han0.00401734See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.70.00385266See
JPNJapan pop 160.003218604See
CHNChina Marrow Donor Registry0.0030600See
VNMVietnam Hanoi Kinh pop 20.0030170See
CHNChina Tibet Region Tibetan0.0030158See
CHNChina South Han pop 20.00271098See
MYSMalaysia Peninsular Chinese0.50.0026194See
USAUSA NMDP Korean0.002277584See
TWNTaiwan Han Chinese0.0020504See
KORSouth Korea pop 30.0020485See
USAUSA Asian pop 20.00201772See
USAUSA NMDP Chinese0.001499672See
DEUGermany DKMS - Portugal minority0.00091176See
USAUSA NMDP Vietnamese0.000743540See
MYSMalaysia Peninsular Malay0.10.0005951See
RUSRussia Nizhny Novgorod, Russians0.10.00031510See
DEUGermany DKMS - Turkey minority0.00034856See
USAUSA NMDP Filipino0.000350614See
USAUSA NMDP Southeast Asian0.000327978See
USAUSA NMDP Hawaiian or other Pacific Islander0.000211499See
DEUGermany pop 80.000139689See
POLPoland BMR0.00.000123595See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000070890See
SAUSaudi Arabia pop 6 (G)0.000028927See
USAUSA NMDP European Caucasian0.00001242890See
DEUGermany DKMS - German donors0.00003456066See
NLDNetherlands Leiden0.00001305See
POLPoland DKMS0.000020653See
USAUSA Hispanic pop 20.00001999See
USAUSA African American pop 40.00002411See
CHNChina Guizhou Province Bouyei0.0000109See
CHNChina Guizhou Province Shui0.0000153See
USAUSA Philadelphia Caucasian0.00.0000141See
CHNChina North Han0.0000105See
USAUSA Alaska Yupik0.0000252See
CZECzech Republic0.0000106See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
FRAFrance West0.00.0000100See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
SENSenegal Niokholo Mandenka0.0000165See
CHESwitzerland Geneva0.000080See
ITAItaly Bergamo0.00.0000101See
USAUSA San Antonio Caucasian0.0000222See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
NIRIreland Northern0.00.00001000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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