Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 79 time(s) and present in 48 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CMRCameroon Bakola Pygmy26.00.139750See
CRICosta Rica African -Caribbean (G)16.60.0930102See
ZAFSouth Africa Worcester17.00.0910159See
UGAUganda Kampala pop 20.0830175See
KENKenya, Nyanza Province, Luo tribe11.00.0650100See
CRICosta Rica Guanacaste Mestizo (G)10.90.0590110See
USAUSA African American pop 30.0580564See
COLColombia/Brazil Ticuna Arara NA-DHS_21 (G)7.10.035717See
ZWEZimbabwe Harare Shona0.0290230See
TZATanzania Maasai5.30.0266336See
COLColombia North Chimila Amerindians0.021247See
ZAFSouth African Mixed ancestry4.00.020050See
AREUnited Arab Emirates Abu Dhabi0.019252See
MEXMexico Mexico City Mestizo population0.0175143See
MARMorocco Nador Metalsa pop 20.016073See
NICNicaragua Mestizo (G)3.20.0160155See
NICNicaragua Managua2.20.0110339See
USAUSA San Diego1.90.0100496See
BRABrazil Mixed0.0090108See
CRICosta Rica Central Valley Mestizo (G)1.40.0070221See
MARMorocco Atlantic Coast Chaouya0.007098See
MARMorocco Settat Chaouya1.40.007098See
USAUSA Mexican American Mestizo0.0060553See
IRNIran Baloch0.0050100See
MEXMexico Mexico City Mestizo pop 20.0043234See
RUSRussia Tuva pop 20.0030169See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.60.00304335See
DEUGermany DKMS - Portugal minority0.00281176See
DEUGermany DKMS - Spain minority0.00271107See
DEUGermany DKMS - Italy minority0.00241159See
DEUGermany DKMS - Netherlands minority0.00201374See
USAUSA Spain Ancestry0.0020279See
USAUSA Italy Ancestry0.0020273See
DEUGermany DKMS - United Kingdom minority0.00141043See
DEUGermany DKMS - France minority0.00111406See
ENGEngland Blood Donors of Mixed Ethnicity0.20.0010519See
INDIndia Kerala Malayalam speaking0.30.0010356See
NLDNetherlands Leiden0.00101305See
CHESwitzerland Bern0.00093545See
USAUSA NMDP Black South or Central American0.00064889See
DEUGermany DKMS - Austria minority0.00061698See
DEUGermany DKMS - Turkey minority0.00054856See
DEUGermany pop 80.000339689See
CZECzech Republic NMDR0.00035099See
DEUGermany DKMS - Croatia minority0.00022057See
ITAItaly pop 50.0000975See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHNChina Tibet Region Tibetan0.0000158See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
CHESwitzerland Aargau-Solothurn0.00001838See
PHLPhilippines Ivatan0.00.000050See
POLPoland DKMS0.000120653See
KORSouth Korea pop 30.0000485See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA Philadelphia Caucasian0.00.0000141See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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