Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 27 time(s) and present in 27 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ESPSpain, Canary Islands, Gran canaria island20.00.1139215See
BRABrazil Barra Mansa Rio State Black0.078673See
USAUSA San Francisco Caucasian0.0580220See
BRABrazil Barra Mansa Rio State Caucasian0.0556405See
CRICosta Rica Central Valley Mestizo (G)10.80.0540221See
CRICosta Rica African -Caribbean (G)10.80.0540102See
BRABrazil Rio de Janeiro Black0.052168See
BRABrazil Rio de Janeiro Caucasian0.0516521See
BRABrazil Rio de Janeiro Parda0.0463170See
ZAFSouth African Mixed ancestry8.00.040050See
ENGEngland Blood Donors of Mixed Ethnicity6.50.0356519See
CRICosta Rica Guanacaste Mestizo (G)6.40.0320110See
NICNicaragua Mestizo (G)6.40.0320155See
RUSRussia Belgorod region5.20.0261153See
ZAFSouth African Black4.90.0247142See
SAUSaudi Arabia pop 6 (G)0.023228927See
RUSRussia Nizhny Novgorod, Russians4.40.02221510See
POLPoland BMR3.40.017023595See
RUSRussian Federation Vologda Region2.50.0126119See
ZAFSouth African Indian population2.00.010050See
SAUSaudi Arabia pop 51.90.0095158See
RUSRussia Bashkortostan, Tatars1.60.0078192See
CRICosta Rica Amerindians (G)0.80.0040125See
USAUSA Arizona Gila River Pima0.00143000See
INDIndia Kerala Malayalam speaking0.30.0010356See
CHNChina Zhejiang Han0.00091734See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.10.00045266See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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