Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 22 time(s) and present in 22 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ZAFSouth African Black20.40.1056142See
CRICosta Rica African -Caribbean (G)17.60.0880102See
ZAFSouth African Mixed ancestry14.00.070050See
BRABrazil Barra Mansa Rio State Black0.064373See
SAUSaudi Arabia pop 6 (G)0.046228927See
BRABrazil Rio de Janeiro Black0.041768See
CRICosta Rica Guanacaste Mestizo (G)6.40.0320110See
BRABrazil Rio de Janeiro Parda0.0231170See
BRABrazil Barra Mansa Rio State Caucasian0.0217405See
BRABrazil Rio de Janeiro Caucasian0.0172521See
NICNicaragua Mestizo (G)2.60.0130155See
CRICosta Rica Central Valley Mestizo (G)1.40.0070221See
USAUSA San Francisco Caucasian0.0070220See
MEXMexico Hidalgo Mezquital Valley/ Otomi1.40.006972See
RUSRussia Nizhny Novgorod, Russians0.90.00431510See
RUSRussian Federation Vologda Region0.80.0042119See
POLPoland BMR0.80.004123595See
INDIndia Kerala Malayalam speaking0.60.0030356See
RUSRussia Bashkortostan, Tatars0.50.0026192See
ENGEngland Blood Donors of Mixed Ethnicity0.40.0019519See
USAUSA Arizona Gila River Pima0.00133000See
CHNChina Zhejiang Han0.00031734See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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