HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 

DRB1*04
Allele reported 404 time(s) and present in 398 population(s).

Population		Phenotype Frequency (%)	Allele Frequency (in_decimals)		Sample Size	IMGT/HLA¹ Database	Distribution²	Haplotype³ Association	Notesª
	Mexico Yucatan, Merida		0.4949		192	See
	Mexico Morelos Rural		0.4667		30	See
	Mexico Campeche, Campeche city		0.4412		34	See
	Mexico Quintana Roo Rural		0.4400		50	See
	Mexico mestizo pop 3		0.4378		201	See
	Mexico Quintana Roo, Cancun		0.4375		48	See
	Mexico Chiapas, Tuxtla Gutierrez		0.4340		52	See
	Mexico Tabasco Rural		0.4331		142	See
	Mexico Guanajuato, Guanajuato city		0.4318		22	See
	Mexico Queretaro, Queretaro city		0.4222		45	See
	Argentina Kolla		0.4200		61	See
	Mexico Yucatan Rural		0.4179		132	See
	Mexico Chiapas Rural		0.4174		121	See
	Argentina Salta Wichi pop 2	63.2	0.3950		19	See
	Guatemala, Guatemala City Mixed Ancestry	59.1	0.3898		127	See
	Mexico Tapachula, Chiapas Mestizo Population	63.9	0.3889		72	See
	Mexico Mexico City East		0.3875		79	See
	Mexico Colima, Colima city		0.3852		61	See
	Mexico Tabasco, Villahermosa		0.3841		82	See
	Mexico Mexico City North		0.3838		751	See
	Mexico Veracruz Rural		0.3651		539	See
	Mexico Campeche Rural		0.3617		47	See
	Mexico Morelos, Cuernavaca		0.3476		82	See
	Mexico Veracruz, Xalapa		0.3476		187	See
	Mexico Guerrero state		0.3403		144	See
	Mexico Veracruz, Veracruz city		0.3401		171	See
	Mexico Baja California, Tijuana		0.3400		25	See
	Mexico Mexico City South		0.3365		52	See
	Mexico Hidalgo Rural		0.3333		81	See
	Mexico Veracruz, Coatzacoalcos		0.3304		55	See
	Mexico Baja California Rural		0.3300		50	See
	Mexico Oaxaca Rural		0.3296		485	See
	Mexico Tlaxcala Rural		0.3289		830	See
	Russia Murmansk Saomi Mixed		0.3270		70	See
	Ecuador Coast Mixed Ancestry		0.3235		238	See
	Mexico Durango, Durango city		0.3226		153	See
	Mexico Tlaxcala, Tlaxcala city		0.3204		181	See
	Mexico Oaxaca, Oaxaca city		0.3179		151	See
	Mexico Tamaulipas Rural		0.3175		125	See
	Mexico Queretaro Rural		0.3140		43	See
	Mexico Puebla, Puebla city		0.3114		1994	See
	Mexico Veracruz, Poza Rica		0.3111		45	See
	Mexico Nayarit Rural		0.3047		64	See
	Mexico Nayarit, Tepic		0.3041		97	See
	Mexico Guanajuato, Leon		0.3013		78	See
	Mexico Michoacan, Morelia		0.2947		150	See
	Mexico Mexico City Metropolitan Area Rural		0.2928		150	See
	Mexico Durango Rural		0.2920		326	See
	Mexico Coahuila, Saltillo		0.2877		72	See
	Mexico Sonora Rural		0.2843		197	See
	Mexico Colima Rural		0.2841		43	See
	Mexico Sonora, Ciudad Obregón		0.2797		143	See
	Mexico Sinaloa Rural		0.2787		183	See
	Mexico Puebla Rural		0.2782		833	See
	Mexico Veracruz, Cordoba		0.2768		56	See
	Chile Huilliche		0.2750		40	See
	Brazil Guarani M bya		0.2740		93	See
	Mexico Aguascalientes state		0.2737		95	See
	Mexico Michoacan Rural		0.2736		348	See
	Mexico Zacatecas, Fresnillo		0.2714		103	See
	Brazil Kaingang		0.2690		235	See
	Taiwan Aborigine		0.2670		111	See
	Mexico Guanajuato Rural		0.2669		162	See
	Mexico Baja California, La Paz		0.2667		75	See
	Mexico San Luis Potosi, San Luis Potosi city		0.2667		30	See
	Mexico Jalisco Rural		0.2654		585	See
	Ecuador Mixed Ancestry		0.2643		1173	See
	Mexico Sinaloa, Culiacán		0.2621		103	See
	Mexico Nuevo Leon Rural		0.2614		439	See
	Mexico Mexico City Mestizo		0.2600		121	See
	Mexico Mexico City Center		0.2597		152	See
	Mexico Chihuahua, Ciudad Juarez		0.2593		106	See
	Mexico Jalisco, Guadalajara city		0.2592		1189	See
	Mexico Hidalgo, Pachuca		0.2561		41	See
	Mexico Zacatecas, Zacatecas city		0.2560		84	See
	Mexico Coahuila, Torreon		0.2525		396	See
	Ecuador Andes Mixed Ancestry		0.2524		824	See
	Mexico Guadalajara Mestizo		0.2500		54	See
	India Tamil Nadu Dravidian		0.2500		156	See
	Mexico Chihuahua Chihuahua City		0.2479		119	See
	Mexico Coahuila Rural		0.2477		216	See
	USA OPTN Hispanic		0.2460		1580	See
	Mexico Chihuahua Rural		0.2448		236	See
	Mexico Baja Californa, Mexicali		0.2400		100	See
	United Kingdom South West		0.2399		163	See
	Armenia Ghegharkunik		0.2380		242	See
	Mexico Sonora, Hermosillo		0.2374		99	See
	Mexico Puebla Mestizo		0.2370		99	See
	Armenia living in USA		0.2360		233	See
	Armenia living in Iran		0.2350		85	See
	Mexico Nuevo Leon, Monterrey city		0.2345		226	See
	Mexico Zacatecas Rural		0.2323		266	See
	Mexico Jalisco, Tlaquepaque		0.2308		39	See
	Mexico Jalisco, Zapopan		0.2262		168	See
	Mexico Veracruz, Orizaba		0.2250		60	See
	Venezuela Zulia Maracaibo Mixed		0.2250		20	See
	Mexico Mestizo pop 4		0.2230		269	See
	Norway pop 2		0.2230		576	See
	Mexico Mexico City West		0.2206		33	See
	Japan pop 8		0.2190		308	See
	Mexico San Luis Potosi Rural		0.2184		87	See
	Ecuador Amazonia Mixed Ancestry		0.2179		39	See
	Armenia Shirak		0.2170		76	See
	Japan pop 10		0.2170		332	See
	Mexico Jalisco, Tlajomulco		0.2167		30	See
	Russia Nenet Mixed		0.2090		55	See
	Wales	36.8	0.2080		1798	See
	Sudan East Rashaida	37.0	0.2062		27	See
	Armenia Lori		0.2060		102	See
	Wales pop 2	36.6	0.2040		39979	See
	United Kingdom pop 2		0.2030		101	See
	Australia West Caucasian	36.3	0.2020		891	See
	England	36.3	0.2018		537	See
	Turkey Ankara		0.2000		50	See
	Norway ethnic Norwegians	36.1	0.2000		4510	See
	Sweden pop 5		0.1990		1569	See
	England Liverpool	35.8	0.1987		1343	See
	Venezuela Valencia and Maracaibo Caracus Mixed		0.1980		96	See
	Armenia living in Karabakh		0.1970		445	See
	Armenia Yerevan		0.1960		445	See
	Mexico Sinaloa Mestizo		0.1960		56	See
	France West Breton		0.1960		150	See
	Ireland Donegal	36.5	0.1950		200	See
	South Korea pop 8		0.1950		7096	See
	United Kingdom East		0.1950		163	See
	Australia South and East Caucasian	35.0	0.1937		1210	See
	Argentina La Plata	35.0	0.1900		100	See
	England Lancaster	34.3	0.1894		545	See
	Sweden Stockholm	34.3	0.1890		1347	See
	Saudi Arabia pop 2		0.1890		383	See
	Armenia Syunik		0.1880		117	See
	England Sheffield	34.0	0.1876		4755	See
	Armenia living in Lebanon		0.1850		368	See
	England Leeds	33.3	0.1833		5024	See
	Georgia Kurds		0.1830		30	See
	England Newcastle	33.2	0.1826		2739	See
	Argentina Corrientes	32.9	0.1810		155	See
	Russia Arkhangelsk Pomor		0.1790		63	See
	Peru Arequipa Mestizo	32.9	0.1790		168	See
	France Rennes pop 4	34.4	0.1787		1000	See
	Sweden pop 4	32.3	0.1775		966	See
	United Kingdom North		0.1774		330	See
	Brazil REDOME Amazonas		0.1768		24129	See
	Ireland South pop 2		0.1758		17624	See
	Ireland Wexford	33.0	0.1750		200	See
	Mexico Tamaulipas, Ciudad Victoria		0.1739		23	See
	United Kingdom Central		0.1729		135	See
	Mexico Jalisco, Tonala		0.1714		35	See
	Brazil REDOME Amapa		0.1712		17864	See
	Myanmar Kayin	29.5	0.1705		44	See
	USA OPTN Caucasian		0.1700		8525	See
	Brazil North East Mixed		0.1700		205	See
	Israel Jews pop 2	31.1	0.1700		23000	See
	Spain Catalonia Girona		0.1670		88	See
	Russia Arkhangelsk		0.1660		81	See
	Jordan		0.1620		15141	See
	Brazil REDOME Roraima		0.1604		4140	See
	Saudi Arabia pop 4	28.8	0.1603		499	See
	Argentina Buenos Aires pop 2	28.7	0.1600		1216	See
	United Kingdom Orkney		0.1595		88	See
	Brazil Para Cord Blood Unit	28.8	0.1576		841	See
	Philippines National Capital Region		0.1570		51	See
	Portugal Castelo Branco		0.1570		327	See
	Portugal Viana do Castelo		0.1570		706	See
	Argentina Cuyo Region	28.8	0.1560		420	See
	Brazil REDOME Para		0.1546		72637	See
	Malaysia Perak and Johor Banjar Bugis Jawa		0.1540		94	See
	Taiwan Hakka pop 2		0.1540		714	See
	Morocco pop 2		0.1530		110	See
	Brazil Parana Oriental	30.3	0.1510		33	See
	England North West Mixed pop 2	28.2	0.1504		379	See
	Taiwan Chinese immigrants from South China		0.1500		172	See
	France Southeast	27.7	0.1500		130	See
	Venezuela Zulia San Jose de Heras Mixed		0.1500		20	See
	Brazil Para State	28.7	0.1500		5000	See
	Spain Majorcans Jews		0.1490		103	See
	Portugal Faro		0.1490		1242	See
	Taiwan Minnan pop 2		0.1480		7137	See
	Brazil REDOME Acre		0.1461		859	See
	Portugal Viseu		0.1450		2915	See
	France Grenoble, Nantes and Rennes		0.1440		6094	See
	Brazil REDOME Paraiba		0.1421		43868	See
	Cuba Mixed pop 2		0.1420		189	See
	Czech Republic Kurd	24.3	0.1419		74	See
	Portugal Aveiro		0.1410		5933	See
	Poland Lodz		0.1410		103	See
	Switzerland Graubunden		0.1403		759	See
	Portugal Coimbra		0.1400		5057	See
	Portugal Portalegre		0.1400		1254	See
	Brazil Rio Grande do Norte Mestizo		0.1400		12973	See
	Brazil REDOME Ceara		0.1394		101217	See
	Portugal Beja		0.1390		699	See
	Portugal Vila Real		0.1390		1167	See
	USA OPTN Asian		0.1390		261	See
	Portugal North pop 2		0.1379		1801	See
	Switzerland St Gallen		0.1375		2113	See
	Switzerland Lausanne		0.1373		993	See
	Brazil REDOME Rio Grande do Norte		0.1369		46603	See
	Switzerland Sion		0.1362		832	See
	Portugal Setubal		0.1360		5268	See
	Portugal Guarda		0.1350		797	See
	Switzerland Basel		0.1350		1888	See
	Brazil REDOME Maranhao		0.1349		10180	See
	Spain, Castilla y Leon, Northwest,	24.2	0.1342		1743	See
	Brazil Rio Grande do Sul Caucasoid		0.1340		4428	See
	Brazil Piaui Mixed		0.1340		21943	See
	Brazil REDOME Mato Grosso do Sul		0.1336		95667	See
	Portugal Lisbon		0.1330		17420	See
	Thailand pop 2		0.1330		124	See
	Brazil REDOME Piaui		0.1326		46140	See
	Spain Northwest	24.7	0.1322		1818	See
	Taiwan Chinese immigrants from North China		0.1320		152	See
	Portugal Porto		0.1320		7937	See
	Brazil REDOME Alagoas		0.1317		25349	See
	Iran pop 4		0.1317		855	See
	Germany	24.6	0.1316		11407	See
	Portugal Center pop 2		0.1310		562	See
	Turkey pop 2		0.1310		228	See
	Pakistan Kalash		0.1300		69	See
	China Beijing and Guangzhou		0.1300		1592	See
	Burkina Faso Fulani		0.1300		49	See
	Switzerland Geneva pop 2		0.1295		1267	See
	Switzerland Bern		0.1290		3545	See
	Portugal Santarem		0.1290		3865	See
	England Manchester	24.1	0.1287		1640	See
	India Tamil Nadu Chennai	24.1	0.1287		137	See
	Turkey Istanbul	24.0	0.1282		250	See
	Portugal South pop 2		0.1280		1021	See
	Brazil REDOME Pernambuco		0.1280		92332	See
	Brazil REDOME Santa Catarina		0.1278		106673	See
	Iraq Kurdistan Region	23.4	0.1270		209	See
	Switzerland Aargau-Solothurn		0.1270		1838	See
	China Shanghai		0.1270		26266	See
	Spain Malaga	23.8	0.1270		160	See
	Bosnia and Herzegovina		0.1268		134	See
	Brazil REDOME Federal District		0.1268		29549	See
	Brazil REDOME Rio Grande do Sul		0.1268		241329	See
	Iraq Erbil	25.3	0.1265		372	See
	Brazil REDOME Goias		0.1263		88574	See
	Brazil REDOME Rondonia		0.1263		54396	See
	Brazil Mato Grosso do Sul		0.1260		203	See
	Azores		0.1260		1050	See
	Portugal Evora		0.1260		737	See
	Brazil Parana Mixed race	25.3	0.1260		186	See
	France Marseille	23.3	0.1255		1000	See
	Brazil REDOME Parana		0.1255		341639	See
	France Lyon	23.8	0.1251		4813	See
	Brazil Rio Grande do Sul Black		0.1250		248	See
	Brazil Rio Grande do Sul Mixed		0.1250		324	See
	Brazil REDOME Mato Grosso		0.1249		34649	See
	China Jiangsu Province		0.1240		20248	See
	Switzerland Zurich		0.1239		4875	See
	Spain Valencia	23.2	0.1236		577	See
	Brazil REDOME Tocantins		0.1233		20692	See
	Portugal Leiria		0.1230		1847	See
	Portugal Braga		0.1220		1971	See
	Brazil Parana Caucasian	24.4	0.1220		2775	See
	Brazil South East Cord Blood		0.1206		11409	See
	France Bordeaux	22.9	0.1204		990	See
	Brazil REDOME Minas Gerais		0.1204		211275	See
	Vietnam Hanoi		0.1200		50	See
	Azores Terceira Island		0.1200		130	See
	France Grenoble	22.8	0.1192		1000	See
	Russia Northwest	21.1	0.1190		1011	See
	Russia Kostroma Region		0.1190		126	See
	Brazil REDOME Sao Paulo		0.1188		800809	See
	Switzerland Lugano		0.1178		1169	See
	China Guangdong Province	22.1	0.1173		403	See
	Taiwan Chinese immigrants from Middle China		0.1170		211	See
	Brazil REDOME Rio de Janeiro		0.1169		139322	See
	Russia South Ural Bashkir	22.6	0.1160		146	See
	Brazil Sao Paulo Mixed	21.8	0.1150		239	See
	Brazil Minas Gerais State Mixed	21.8	0.1150		1000	See
	Thailand pop 4		0.1140		16807	See
	Brazil South Ribeirao Preto		0.1130		184	See
	Russia Northwest pop 2	21.1	0.1120		346	See
	China Shaanxi Province Han		0.1120		10000	See
	Slovakia		0.1120		146	See
	Brazil REDOME Bahia		0.1116		47399	See
	Brazil REDOME Sergipe		0.1115		7321	See
	Austria Cord Bloods		0.1113		1368	See
	Russia Tatars		0.1112		355	See
	Spain Madrid	21.0	0.1111		504	See
	United Arab Emirates pop 2	20.9	0.1110		373	See
	Brazil REDOME Espirito Santo		0.1104		88485	See
	Portugal Bragança		0.1100		301	See
	Malaysia Perak Rawa		0.1100		23	See
	Russia Moscow		0.1100		2650	See
	Russia South Ural Russian	19.8	0.1090		207	See
	Spain Minorca		0.1090		94	See
	Italy pop 6	20.1	0.1087		184	See
	Brazil Curitiba-Parana Mixed		0.1086		264	See
	Slovakia pop 2		0.1082		4234	See
	Brazil Parana Cafuzo	21.6	0.1080		319	See
	China Han	20.4	0.1078		314	See
	India Andhra Pradesh Brahmin	5.5	0.1070		98	See
	Russia Moscow Pop 2	20.5	0.1068		2000	See
	Czech Republic pop 3	21.1	0.1060		180	See
	Madeira pop 3		0.1060		538	See
	India Bikaner Non-Raikas	20.2	0.1060		127	See
	Spain North	20.0	0.1055		156	See
	India Andhra Pradesh Sunni	5.4	0.1050		100	See
	Bosnia and Herzegovina pop 2	20.0	0.1042		120	See
	Iran Royan Cord Blood Bank	19.7	0.1040		15600	See
	Russia Samara Region		0.1040		2500	See
	Myanmar Kachin	19.0	0.1032		63	See
	Russia Smolensk		0.1030		156	See
	Iran		0.1030		58	See
	Greece North		0.1030		500	See
	Bangladesh Dhaka Bangalee		0.1020		141	See
	Myanmar Shan	20.4	0.1019		54	See
	China Shandong Province	19.1	0.1000		7418	See
	France South	19.0	0.1000		350	See
	Poland pop 3	19.9	0.0998		2907	See
	Spain Majorca		0.0990		407	See
	Pakistan Karachi Parsi		0.0980		91	See
	Russia, South Ural, Chelyabinsk region, Nagaybaks	17.0	0.0980		112	See
	Myanmar Bamar	17.4	0.0978		46	See
	Albanian Kosovo		0.0958		120	See
	Croatia Gorski Kotar Region		0.0950		63	See
	Greece pop 7		0.0948		11250	See
	Brazil Sao Paulo Bauru Mixed		0.0920		3542	See
	Croatia pop 3	18.3	0.0917		120	See
	Serbia Vojvodina	17.0	0.0910		400	See
	India North pop 3		0.0900		587	See
	Romania pop 2		0.0900		6936	See
	Serbia pop 3	17.0	0.0899		1992	See
	Russia South Ural Tatar	17.0	0.0890		135	See
	Italy Lombardy	17.1	0.0890		674	See
	Romania pop 3	17.1	0.0880		1469	See
	Serbia		0.0880		386	See
	India New Delhi pop 2		0.0880		102	See
	Switzerland Luzern		0.0879		1553	See
	Iraq Arabs	17.4	0.0872		149	See
	Spain Andalusia Romani		0.0870		99	See
	Russia North Ossetian	17.3	0.0866		127	See
	Myanmar Mon	17.2	0.0859		64	See
	India North Gujarat	15.9	0.0856		338	See
	Spain Ibiza		0.0850		88	See
	Italy North pop 2	16.2	0.0850		2054	See
	Myanmar Rakhine	16.7	0.0833		48	See
	China Shandong Province Linqu County	15.8	0.0823		139	See
	Albania pop 2	15.7	0.0822		432	See
	Italy North Pavia pop 2	16.4	0.0820		2416	See
	Italy Central		0.0820		380	See
	Macedonia		0.0804		286	See
	Italy		0.0800		159311	See
	Norway Sami		0.0800		200	See
	Russia Northwest pop 3	16.0	0.0800		100	See
	Italy North Pavia pop 3		0.0792		685	See
	Italy pop 4	15.2	0.0790		4575	See
	Macedonia MBMDR - Macedonian Muslims	14.5	0.0789		76	See
	Brazil Southeast Campinas Mixed	15.1	0.0785		99	See
	Senegal Dakar	15.6	0.0780		112	See
	Finland		0.0780		91	See
	Brazil Parana Afro Brazilian	15.6	0.0780		77	See
	Albania		0.0780		160	See
	Greece pop 5		0.0770		500	See
	Italy pop 2		0.0760		53	See
	Italy Sardinia		0.0760		86	See
	Macedonia MBMDR - Macedonian	13.9	0.0729		1283	See
	Malaysia pop 2		0.0710		62	See
	Spain Gipuzkoa Basque		0.0710		100	See
	Croatia pop 2		0.0690		100	See
	Sri Lanka Colombo Sinhalese		0.0690		101	See
	Italy South Campania Region	13.3	0.0688		1089	See
	Sudan Khartoum		0.0663		98	See
	Spain Malaga Romani	12.5	0.0645		80	See
	Malaysia pop 3		0.0640		1445	See
	South Africa Limpopo Venda		0.0640		117	See
	Trinidad African		0.0600		67	See
	Sudan Central Shaigiya Mixed	11.1	0.0571		36	See
	Sudan South Nuba	10.9	0.0560		46	See
	Macedonia MBMDR - Albanian	10.2	0.0547		128	See
	India Bikaner Raikas	10.4	0.0540		143	See
	India sub-Himalayan West Bengal Kami	10.8	0.0538		158	See
	USA Southeast African American	8.9	0.0490		112	See
	Jamaica		0.0490		132	See
	Pakistan Burusho		0.0480		92	See
	Myanmar Kayah	9.1	0.0455		55	See
	USA OPTN African American		0.0450		1510	See
	Greece	8.0	0.0410		48	See
	Trinidad South Asian		0.0400		87	See
	Myanmar Chin	7.3	0.0364		55	See
	Colombia Guajira Peninsula Wayuu		0.0360		88	See
	Czech Republic Romani pop 2	6.5	0.0326		46	See
	Malaysia Negeri Sembilan Minangkabau		0.0300		34	See
	Rwanda		0.0260		280	See
	Italy North Pavia		0.0250		81	See
	Peru Quechua		0.0230		44	See
	Colombia Bogota and Medellin Mestizo		0.0230		65	See
	Mozambique		0.0210		202	See
	Tanzania Dodoma Kongwa		0.0190		212	See
	Pakistan Baloch		0.0090		66	See
	Colombia Sierra Nevada de Santa Marta Arhuaco		0.0080		107	See
	Colombia Sierra Nevada de Santa Marta Kogi		0.0080		42	See
	Ghana Accre Asutuare Akan		0.0030		429	See
	Pakistan Brahui		0.0000		104	See
	Pakistan Mixed Pathan		0.0000		100	See
	Pakistan Mixed Sindhi		0.0000		101	See
	Equatorial Guinea Bioko Island Bubi		0.0000		100	See
	Burkina Faso Mossi		0.0000		53	See
	Burkina Faso Rimaibe		0.0000		47	See

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.