Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

DRB1*04

 
Allele reported 388 time(s) and present in 382 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
MEXMexico Yucatan, Merida0.4949192See
MEXMexico Yucatan state0.4635324See
MEXMexico Campeche, Campeche city0.441234See
MEXMexico Quintana Roo0.438898See
MEXMexico mestizo pop 30.4378201See
MEXMexico Quintana Roo, Cancun0.437548See
MEXMexico Chiapas, Tuxtla Gutierrez0.434052See
MEXMexico Guanajuato, Guanajuato city0.431822See
MEXMexico Chiapas state0.4224173See
MEXMexico Queretaro, Queretaro city0.422245See
ARGArgentina Kolla0.420061See
MEXMexico Tabasco state0.4152224See
MEXMexico Campeche state0.395181See
ARGArgentina Salta Wichi pop 263.20.395019See
MEXMexico Mexico City East0.387579See
MEXMexico Colima, Colima city0.385261See
MEXMexico Tabasco, Villahermosa0.384182See
MEXMexico Mexico City North0.3838751See
MEXMexico Morelos state0.3795112See
MEXMexico Queretaro state0.369388See
MEXMexico Morelos, Cuernavaca0.347682See
MEXMexico Veracruz, Xalapa0.3476187See
MEXMexico Veracruz state0.34531134See
MEXMexico Colima state0.3429105See
MEXMexico Guerrero state0.3403144See
MEXMexico Veracruz, Veracruz city0.3401171See
MEXMexico Mexico City South0.336552See
MEXMexico Veracruz, Coatzacoalcos0.330455See
MEXMexico Tlaxcala state0.32741011See
RUSRussia Murmansk Saomi Mixed0.327070See
MEXMexico Oaxaca state0.3268636See
ECUEcuador Coast Mixed Ancestry0.3235238See
MEXMexico Durango, Durango city0.3226153See
MEXMexico Tlaxcala, Tlaxcala city0.3204181See
MEXMexico Oaxaca, Oaxaca city0.3179151See
MEXMexico Mexico City Metropolitan Area0.31754590See
MEXMexico Puebla, Puebla city0.31141994See
MEXMexico Veracruz, Poza Rica0.311145See
MEXMexico Hidalgo state0.3074122See
MEXMexico Nayarit0.3043161See
MEXMexico Nayarit, Tepic0.304197See
MEXMexico Durango state0.3019476See
MEXMexico Puebla state0.30162827See
MEXMexico Guanajuato, Leon0.301378See
MEXMexico Tamaulipas state0.2953148See
MEXMexico Michoacan, Morelia0.2947150See
MEXMexico Guanajuato state0.2909263See
MEXMexico Coahuila, Saltillo0.287772See
MEXMexico Michoacan0.2800498See
MEXMexico Sonora, Ciudad Obregón0.2797143See
MEXMexico Veracruz, Cordoba0.276856See
CHLChile Huilliche0.275040See
MEXMexico Baja California0.2749250See
BRABrazil Guarani M bya0.274093See
MEXMexico Aguascalientes state0.273795See
MEXMexico Sinaloa state0.2727286See
MEXMexico Sonora state0.2722439See
MEXMexico Zacatecas, Fresnillo0.2714103See
BRABrazil Kaingang0.2690235See
TWNTaiwan Aborigine0.2670111See
MEXMexico Baja California, La Paz0.266775See
MEXMexico San Luis Potosi, San Luis Potosi city0.266730See
ECUEcuador Mixed Ancestry0.26431173See
MEXMexico Sinaloa, Culiacán0.2621103See
MEXMexico Mexico City Mestizo0.2600121See
MEXMexico Mexico City Center0.2597152See
MEXMexico Chihuahua, Ciudad Juarez0.2593106See
MEXMexico Jalisco, Guadalajara city0.25921189See
MEXMexico Hidalgo, Pachuca0.256141See
MEXMexico Zacatecas, Zacatecas city0.256084See
MEXMexico Coahuila state0.2547683See
MEXMexico Jalisco state0.25462055See
MEXMexico Coahuila, Torreon0.2525396See
ECUEcuador Andes Mixed Ancestry0.2524824See
MEXMexico Nuevo Leon state0.2523665See
INDIndia Tamil Nadu Dravidian0.2500156See
MEXMexico Guadalajara Mestizo0.250054See
MEXMexico Chihuahua state0.2489461See
MEXMexico Chihuahua, Chihuahua city0.2479119See
USAUSA OPTN Hispanic0.24601580See
MEXMexico Zacatecas state0.2456453See
MEXMexico Baja Californa, Mexicali0.2400100See
GBRUnited Kingdom South West0.2399163See
ARMArmenia Ghegharkunik0.2380242See
MEXMexico Sonora, Hermosillo0.237499See
MEXMexico Puebla Mestizo0.237099See
ARMArmenia living in USA0.2360233See
ARMArmenia living in Iran0.235085See
CRICosta Rica Central Valley Mestizo36.20.2350130See
MEXMexico Nuevo Leon, Monterrey city0.2345226See
MEXMexico San Luis Potosi state0.2308117See
MEXMexico Jalisco, Tlaquepaque0.230839See
MEXMexico Jalisco, Zapopan0.2262168See
MEXMexico Veracruz, Orizaba0.225060See
VENVenezuela Zulia Maracaibo Mixed0.225020See
NORNorway pop 20.2230576See
MEXMexico Mestizo pop 40.2230269See
MEXMexico Mexico City West0.220633See
JPNJapan pop 80.2190308See
ECUEcuador Amazonia Mixed Ancestry0.217939See
JPNJapan pop 100.2170332See
ARMArmenia Shirak0.217076See
MEXMexico Jalisco, Tlajomulco0.216730See
RUSRussia Nenet Mixed0.209055See
WALWales36.80.20801798See
SDNSudan East Rashaida37.00.206227See
ARMArmenia Lori0.2060102See
WALWales pop 236.60.204039979See
GBRUnited Kingdom pop 20.2030101See
AUSAustralia West Caucasian36.30.2020891See
ENGEngland36.30.2018537See
TURTurkey Ankara0.200050See
NORNorway ethnic Norwegians36.10.20004510See
SWESweden pop 50.19901569See
ENGEngland Liverpool35.80.19871343See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.198096See
ARMArmenia living in Karabakh0.1970445See
ARMArmenia Yerevan0.1960445See
FRAFrance West Breton0.1960150See
MEXMexico Sinaloa Mestizo0.196056See
IRLIreland Donegal36.50.1950200See
KORSouth Korea pop 80.19507096See
GBRUnited Kingdom East0.1950163See
AUSAustralia South and East Caucasian35.00.19371210See
ARGArgentina La Plata35.00.1900100See
ENGEngland Lancaster34.30.1894545See
SWESweden Stockholm34.30.18901347See
SAUSaudi Arabia pop 20.1890383See
ARMArmenia Syunik0.1880117See
ENGEngland Sheffield34.00.18764755See
ARMArmenia living in Lebanon0.1850368See
ENGEngland Leeds33.30.18335024See
GEOGeorgia Kurds0.183030See
ENGEngland Newcastle33.20.18262739See
ARGArgentina Corrientes32.90.1810155See
RUSRussia Arkhangelsk Pomor0.179063See
PERPeru Arequipa Mestizo32.90.1790168See
FRAFrance Rennes pop 434.40.17871000See
SWESweden pop 432.30.1775966See
GBRUnited Kingdom North0.1774330See
BRABrazil REDOME Amazonas0.176824129See
IRLIreland South pop 20.175817624See
IRLIreland Wexford33.00.1750200See
MEXMexico Tamaulipas, Ciudad Victoria0.173923See
GBRUnited Kingdom Central0.1729135See
MEXMexico Jalisco, Tonala0.171435See
BRABrazil REDOME Amapa0.171217864See
MMRMyanmar Kayin29.50.170544See
USAUSA OPTN Caucasian0.17008525See
BRABrazil North East Mixed0.1700205See
ISRIsrael Jews pop 231.10.170023000See
ESPSpain Catalonia Girona0.167088See
RUSRussia Arkhangelsk0.166081See
GBRUnited Kingdom renal patients29.80.16507007See
JORJordan0.162015141See
BRABrazil REDOME Roraima0.16044140See
SAUSaudi Arabia pop 428.80.1603499See
ARGArgentina Buenos Aires pop 228.70.16001216See
GBRUnited Kingdom Orkney0.159588See
PRTPortugal Viana do Castelo0.1570706See
PRTPortugal Castelo Branco0.1570327See
ARGArgentina Cuyo Region28.80.1560420See
BRABrazil REDOME Para0.154672637See
TWNTaiwan Hakka pop 20.1540714See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.154094See
MARMorocco pop 20.1530110See
BRABrazil Parana Oriental30.30.151033See
ENGEngland North West Mixed pop 228.20.1504379See
VENVenezuela Zulia San Jose de Heras Mixed0.150020See
TWNTaiwan Chinese immigrants from South China0.1500172See
FRAFrance Southeast27.70.1500130See
ESPSpain Majorcans Jews0.1490103See
PRTPortugal Faro0.14901242See
TWNTaiwan Minnan pop 20.14807137See
BRABrazil REDOME Acre0.1461859See
PRTPortugal Viseu0.14502915See
FRAFrance Grenoble, Nantes and Rennes0.14406094See
BRABrazil REDOME Paraiba0.142143868See
CUBCuba Mixed pop 20.1420189See
CZECzech Republic Kurd24.30.141974See
PRTPortugal Aveiro0.14105933See
POLPoland Lodz0.1410103See
CHESwitzerland Graubunden0.1403759See
PRTPortugal Coimbra0.14005057See
PRTPortugal Portalegre0.14001254See
BRABrazil Rio Grande do Norte Mestizo0.140012973See
BRABrazil REDOME Ceara0.1394101217See
USAUSA OPTN Asian0.1390261See
PRTPortugal Beja0.1390699See
PRTPortugal Vila Real0.13901167See
PRTPortugal North pop 20.13791801See
CHESwitzerland St Gallen0.13752113See
CHESwitzerland Lausanne0.1373993See
BRABrazil REDOME Rio Grande do Norte0.136946603See
CHESwitzerland Sion0.1362832See
PRTPortugal Setubal0.13605268See
PRTPortugal Guarda0.1350797See
CHESwitzerland Basel0.13501888See
BRABrazil REDOME Maranhao0.134910180See
BRABrazil Rio Grande do Sul Caucasoid0.13404428See
BRABrazil Piaui Mixed0.134021943See
BRABrazil REDOME Mato Grosso do Sul0.133695667See
THAThailand pop 20.1330124See
PRTPortugal Lisbon0.133017420See
BRABrazil REDOME Piaui0.132646140See
ESPSpain Northwest24.70.13221818See
PRTPortugal Porto0.13207937See
TWNTaiwan Chinese immigrants from North China0.1320152See
BRABrazil REDOME Alagoas0.131725349See
DEUGermany24.60.131611407See
PRTPortugal Center pop 20.1310562See
TURTurkey pop 20.1310228See
CHNChina Beijing and Guangzhou0.13001592See
PAKPakistan Kalash0.130069See
BFABurkina Faso Fulani0.130049See
CHESwitzerland Geneva pop 20.12951267See
CHESwitzerland Bern0.12903545See
PRTPortugal Santarem0.12903865See
INDIndia Tamil Nadu Chennai24.10.1287137See
ENGEngland Manchester24.10.12871640See
TURTurkey Istanbul24.00.1282250See
PRTPortugal South pop 20.12801021See
BRABrazil REDOME Pernambuco0.128092332See
BRABrazil REDOME Santa Catarina0.1278106673See
CHESwitzerland Aargau-Solothurn0.12701838See
KURIraq Kurdistan Region23.40.1270209See
ESPSpain Malaga23.80.1270160See
CHNChina Shanghai0.127026266See
BIHBosnia and Herzegovina0.1268134See
BRABrazil REDOME Federal District0.126829549See
BRABrazil REDOME Rio Grande do Sul0.1268241329See
IRQIraq Erbil25.30.1265372See
BRABrazil REDOME Rondonia0.126354396See
BRABrazil REDOME Goias0.126388574See
BRABrazil Mato Grosso do Sul0.1260203See
PRTAzores0.12601050See
PRTPortugal Evora0.1260737See
BRABrazil Parana Mulatto25.30.1260186See
FRAFrance Marseille23.30.12551000See
BRABrazil REDOME Parana0.1255341639See
FRAFrance Lyon23.80.12514813See
BRABrazil Rio Grande do Sul Black0.1250248See
BRABrazil Rio Grande do Sul Mixed0.1250324See
BRABrazil REDOME Mato Grosso0.124934649See
CHNChina Jiangsu Province0.124020248See
CHESwitzerland Zurich0.12394875See
ESPSpain Valencia23.20.1236577See
BRABrazil REDOME Tocantins0.123320692See
PRTPortugal Leiria0.12301847See
PRTPortugal Braga0.12201971See
BRABrazil Parana Caucasian24.40.12202775See
FRAFrance Bordeaux22.90.1204990See
BRABrazil REDOME Minas Gerais0.1204211275See
PRTAzores Terceira Island0.1200130See
VNMVietnam Hanoi0.120050See
FRAFrance Grenoble22.80.11921000See
RUSRussia Kostroma Region0.1190126See
RUSRussia Northwest21.10.11901011See
BRABrazil REDOME Sao Paulo0.1188800809See
CHESwitzerland Lugano0.11781169See
CHNChina Guangdong Province22.10.1173403See
TWNTaiwan Chinese immigrants from Middle China0.1170211See
BRABrazil REDOME Rio de Janeiro0.1169139322See
RUSRussia South Ural Bashkir22.60.1160146See
BRABrazil Minas Gerais State Mixed21.80.11501000See
BRABrazil Sao Paulo Mixed21.80.1150239See
THAThailand pop 40.114016807See
BRABrazil South Ribeirao Preto0.1130184See
RUSRussia Northwest pop 221.10.1120346See
CHNChina Shaanxi Province Han0.112010000See
SVKSlovakia0.1120146See
BRABrazil REDOME Bahia0.111647399See
BRABrazil REDOME Sergipe0.11157321See
RUSRussia Tatars0.1112355See
ESPSpain Madrid21.00.1111504See
AREUnited Arab Emirates pop 220.90.1110373See
BRABrazil REDOME Espirito Santo0.110488485See
RUSRussia Moscow0.11002650See
PRTPortugal Bragança0.1100301See
MYSMalaysia Perak Rawa0.110023See
RUSRussia South Ural Russian19.80.1090207See
ESPSpain Minorca0.109094See
ITAItaly pop 620.10.1087184See
BRABrazil Curitiba-Parana Mixed0.1086264See
SVKSlovakia pop 20.10824234See
BRABrazil Parana Cafuzo21.60.1080319See
CHNChina Han20.40.1078314See
INDIndia Andhra Pradesh Brahmin5.50.107098See
RUSRussia Moscow pop 220.50.10682000See
CZECzech Republic pop 321.10.1060180See
PRTMadeira pop 30.1060538See
ESPSpain North20.00.1055156See
INDIndia Andhra Pradesh Sunni5.40.1050100See
BIHBosnia and Herzegovina pop 220.00.1042120See
RUSRussia Samara Region0.10402500See
IRNIran Royan Cord Blood Bank19.70.104015600See
MMRMyanmar Kachin19.00.103263See
RUSRussia Smolensk0.1030156See
IRNIran0.103058See
GRCGreece North0.1030500See
BGDBangladesh Dhaka Bangalee0.1020141See
MMRMyanmar Shan20.40.101954See
CHNChina Shandong Province19.10.10007418See
FRAFrance South19.00.1000350See
POLPoland pop 319.90.09982907See
ESPSpain Majorca0.0990407See
PAKPakistan Karachi Parsi0.098091See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks17.00.0980112See
ALBAlbanian Kosovo0.0958120See
MMRMyanmar Bamar17.00.095747See
HRVCroatia Gorski Kotar Region0.095063See
GRCGreece pop 70.094811250See
BRABrazil Sao Paulo Bauru Mixed0.09203542See
HRVCroatia pop 318.30.0917120See
SRBSerbia Vojvodina17.00.0910400See
INDIndia North pop 30.0900587See
ROMRomania pop 20.09006936See
SRBSerbia pop 317.00.08991992See
RUSRussia South Ural Tatar17.00.0890135See
ITAItaly Lombardy17.10.0890674See
SRBSerbia0.0880386See
INDIndia New Delhi pop 20.0880102See
ROMRomania pop 317.10.08801469See
CHESwitzerland Luzern0.08791553See
ESPSpain Andalusia Gipsy0.087099See
RUSRussia North Ossetian17.30.0866127See
MMRMyanmar Mon17.20.085964See
INDIndia North Gujarat15.90.0856338See
ESPSpain Ibiza0.085088See
ITAItaly North pop 216.20.08502054See
MMRMyanmar Rakhine16.70.083348See
CHNChina Shandong Province Linqu County15.80.0823139See
ALBAlbania pop 215.70.0822432See
ITAItaly Central0.0820380See
ITAItaly North Pavia pop 216.40.08202416See
MKDMacedonia0.0804286See
MYSMalaysia Kelantan pop 10.080025See
NORNorway Sami0.0800200See
RUSRussia Northwest pop 316.00.0800100See
ITAItaly0.0800159311See
ITAItaly North Pavia pop 30.0792685See
ITAItaly pop 415.20.07904575See
BRABrazil Southeast Campinas Mixed15.10.078599See
BRABrazil Parana Afro Brazilian15.60.078077See
FINFinland0.078091See
ALBAlbania0.0780160See
SENSenegal Dakar15.60.0780112See
GRCGreece pop 50.0770500See
ITAItaly pop 20.076053See
ITAItaly Sardinia0.076086See
MYSMalaysia pop 20.071062See
ESPSpain Gipuzkoa Basque0.0710100See
HRVCroatia pop 20.0690100See
LKASri Lanka Colombo Sinhalese0.0690101See
ITAItaly South Campania Region13.30.06881089See
ESPSpain Malaga Gypsy12.50.064580See
MYSMalaysia pop 30.06401445See
ZAFSouth Africa Limpopo Venda0.0640117See
TTOTrinidad African0.060067See
SDNSudan Central Shaigiya Mixed11.10.057136See
SDNSudan South Nuba10.90.056046See
USAUSA Southeast African American8.90.0490112See
JAMJamaica0.0490132See
PAKPakistan Burusho0.048092See
MMRMyanmar Kayah9.10.045555See
USAUSA OPTN African American0.04501510See
GRCGreece8.00.041048See
TTOTrinidad South Asian0.040087See
MMRMyanmar Chin7.30.036455See
COLColombia Guajira Peninsula Wayuu0.036088See
CZECzech Republic Gypsy pop 26.50.032646See
MYSMalaysia Negeri Sembilan Minangkabau0.030034See
RWARwanda0.0260280See
ITAItaly North Pavia0.025081See
COLColombia Bogota and Medellin Mestizo0.023065See
PERPeru Quechua0.023044See
MOZMozambique0.0210202See
TZATanzania Dodoma Kongwa0.0190212See
PAKPakistan Baloch0.009066See
COLColombia Sierra Nevada de Santa Marta Arhuaco0.0080107See
COLColombia Sierra Nevada de Santa Marta Kogi0.008042See
GHAGhana Accre Asutuare Akan0.0030429See
PAKPakistan Brahui0.0000104See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
GNQEquatorial Guinea Bioko Island Bubi0.0000100See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

support@allelefrequencies.net


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