Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 25 time(s) and present in 25 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ZAFSouth African Black12.80.0704142See
CRICosta Rica African -Caribbean (G)7.80.0390102See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
CRICosta Rica Central Valley Mestizo (G)5.40.0270221See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
LBYLibya Cyrenaica0.0210118See
CRICosta Rica Guanacaste Mestizo (G)3.60.0180110See
BRABrazil Rio de Janeiro Parda0.0178170See
ESPSpain, Canary Islands, Gran canaria island3.30.0163215See
BRABrazil Rio de Janeiro Caucasian0.0144521See
BRABrazil Barra Mansa Rio State Black0.013773See
BRABrazil Barra Mansa Rio State Caucasian0.0136405See
MEXMexico Chihuahua Tarahumara0.011044See
USAUSA Mexican American Mestizo0.0090553See
CRICosta Rica Amerindians (G)1.60.0080125See
BRABrazil Rio de Janeiro Black0.007468See
USAUSA Italy Ancestry0.0050273See
USAUSA Spain Ancestry0.0040279See
SAUSaudi Arabia pop 50.60.0032158See
NICNicaragua Mestizo (G)0.60.0030155See
ENGEngland North West0.30.0020298See
USAUSA San Francisco Caucasian0.0020220See
POLPoland BMR0.20.001123595See
USAUSA Arizona Gila River Pima0.00023000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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