Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 391 time(s) and present in 379 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
BFABurkina Faso Fulani0.290049See
GHAGhana Accre Asutuare Akan0.2470429See
SDNSudan Central Shaigiya Mixed41.70.236436See
SDNSudan Mixed44.00.2330200See
INDIndia Tamil Nadu Dravidian0.2310156See
RUSRussia North Ossetian38.60.2165127See
BFABurkina Faso Mossi0.210053See
USAUSA Southeast African American36.60.2050112See
PRTPortugal Castelo Branco0.1970327See
INDIndia Bikaner Non-Raikas35.30.1960127See
ESPSpain Northwest Lugo35.20.1950145See
SDNSudan South Nuba34.80.192546See
USAUSA OPTN African American0.18701510See
INDIndia Bikaner Raikas33.60.1850143See
GABGabon Haut-Ogooue Dienga0.1800167See
MKDMacedonia MBMDR - Albanian30.50.1797128See
PRTPortugal South pop 20.17501021See
USAUSA OPTN Hispanic0.17301580See
PRTPortugal Bragança0.1730301See
IRQIraq Arabs26.90.1711149See
PRTPortugal Beja0.1710699See
MEXMexico Sinaloa Mestizo0.170056See
RUSRussia Northwest pop 331.00.1650100See
BLRBelarus Vitebsk Region0.165070See
PRTPortugal Viseu0.16402915See
PRTPortugal Santarem0.16303865See
PRTPortugal Guarda0.1620797See
PRTMadeira pop 30.1620538See
TTOTrinidad African0.160067See
PRTPortugal North pop 20.15931801See
PRTPortugal Portalegre0.15901254See
FRAFrance Southeast29.20.1590130See
BRABrazil REDOME Rio Grande do Norte0.158346603See
PRTPortugal Faro0.15801242See
ESPSpain Madrid29.00.1573504See
BRABrazil Minas Gerais State Mixed28.40.15701000See
PRTPortugal Leiria0.15701847See
PRTPortugal Setubal0.15605268See
CZECzech Republic Kurd27.00.155474See
BRABrazil Rio Grande do Norte Mestizo0.155012973See
BRABrazil Mato Grosso do Sul0.1550203See
RUSRussia South Ural Bashkir27.40.1540146See
PRTPortugal Lisbon0.153017420See
INDIndia New Delhi pop 20.1520102See
PAKPakistan Mixed Sindhi0.1520101See
PRTPortugal Braga0.15101971See
PRTPortugal Aveiro0.15105933See
BRABrazil Rio Grande do Sul Black0.1510248See
PRTPortugal Coimbra0.15005057See
HRVCroatia Gorski Kotar Region0.150063See
BFABurkina Faso Rimaibe0.150047See
ROMRomania pop 20.15006936See
RUSRussia Vologda0.1490121See
INDIndia Andhra Pradesh Brahmin7.70.148098See
BRABrazil REDOME Sergipe0.14777321See
PRTPortugal Vila Real0.14701167See
BRABrazil Sao Paulo Mixed27.70.1470239See
MEXMexico Baja California, La Paz0.146775See
PRTPortugal Viana do Castelo0.1460706See
PRTPortugal Evora0.1460737See
USAUSA OPTN Caucasian0.14508525See
USAUSA OPTN Asian0.1450261See
BRABrazil REDOME Paraiba0.144943868See
TURTurkey Istanbul26.80.1444250See
BRABrazil REDOME Tocantins0.144220692See
PRTPortugal Porto0.14407937See
RUSRussia South Ural Tatar27.40.1440135See
LKASri Lanka Colombo Sinhalese0.1440101See
SAUSaudi Arabia pop 425.90.1439499See
FRAFrance Bordeaux27.70.1437990See
BRABrazil REDOME Bahia0.143647399See
SWESweden Stockholm26.60.14301347See
BRABrazil REDOME Goias0.140488574See
BRABrazil REDOME Federal District0.140329549See
BRABrazil REDOME Rio de Janeiro0.1401139322See
SWESweden pop 50.14001569See
PAKPakistan Burusho0.140092See
NORNorway ethnic Norwegians26.30.13994510See
ESPSpain Northwest26.00.13971818See
FRAFrance Grenoble, Nantes and Rennes0.13906094See
JPNJapan Aichi26.10.139050See
RUSRussia Moscow0.13902650See
BRABrazil REDOME Piaui0.138646140See
BRABrazil REDOME Minas Gerais0.1383211275See
BRABrazil REDOME Maranhao0.138110180See
SAUSaudi Arabia pop 20.1380383See
BRABrazil REDOME Alagoas0.137925349See
BIHBosnia and Herzegovina pop 224.20.1375120See
BRABrazil REDOME Pernambuco0.137492332See
BRABrazil REDOME Ceara0.1373101217See
ARMArmenia Lori0.1370102See
RUSRussia Moscow Pop 226.00.13702000See
BRABrazil Piaui Mixed0.137021943See
BRABrazil South Ribeirao Preto0.1370184See
PRTAzores Terceira Island0.1370130See
BRABrazil Parana Mulatto27.40.1370186See
CZECzech Republic pop 325.00.1360180See
BRABrazil Rio Grande do Sul Caucasoid0.13604428See
BRABrazil REDOME Mato Grosso0.135834649See
BRABrazil REDOME Rondonia0.135354396See
BRABrazil Rio Grande do Sul Mixed0.1350324See
AUTAustria Cord Bloods0.13501368See
BRABrazil REDOME Espirito Santo0.134388485See
RUSRussia Samara Region0.13402500See
MEXMexico Jalisco, Tlajomulco0.133330See
BRABrazil South East Cord Blood0.133111409See
BRABrazil REDOME Sao Paulo0.1326800809See
SWESweden pop 425.70.1325966See
SRBSerbia pop 324.90.13231992See
FRAFrance Rennes pop 425.40.13211000See
BRABrazil REDOME Rio Grande do Sul0.1320241329See
BRABrazil REDOME Santa Catarina0.1314106673See
ISRIsrael Jews pop 224.60.131023000See
FRAFrance South24.50.1310350See
FRAFrance Lyon25.20.13084813See
PAKPakistan Kalash0.130069See
ESPSpain Minorca0.130094See
INDIndia Andhra Pradesh Sunni6.70.1300100See
JPNJapan pop 80.1300308See
ALBAlbanian Kosovo0.1292120See
BRABrazil Sao Paulo Bauru Mixed0.12903542See
ESPSpain Valencia24.10.1287577See
BRABrazil REDOME Mato Grosso do Sul0.128695667See
BRABrazil REDOME Parana0.1286341639See
ARMArmenia living in USA0.1270233See
RUSRussia Northwest pop 223.70.1270346See
RUSRussia South Ural Russian24.20.1260207See
BRABrazil REDOME Roraima0.12514140See
ITAItaly pop 623.90.1250184See
MARMorocco pop 20.1250110See
ITAItaly North Pavia pop 30.1250685See
VENVenezuela Zulia Maracaibo Mixed0.125020See
ARGArgentina La Plata24.00.1250100See
PRTPortugal Center pop 20.1250562See
INDIndia North Gujarat22.80.1246338See
RUSRussia Northwest23.70.12401011See
BRABrazil REDOME Acre0.1234859See
TZATanzania Dodoma Kongwa0.1230212See
UKRUkraine Khmelnytskyi0.1230138See
ITAItaly North Pavia pop 223.00.12302416See
ITAItaly North pop 233.40.12302054See
BRABrazil Parana Afro Brazilian24.70.123077See
HRVCroatia pop 324.20.1208120See
FRAFrance Grenoble23.30.12031000See
BRABrazil REDOME Para0.120272637See
POLPoland pop 323.90.12002907See
BLRBelarus Brest Region0.1190105See
ITAItaly Lombardy21.80.1190674See
FRAFrance Marseille22.80.11881000See
INDIndia North pop 30.1184587See
ARMArmenia living in Iran0.118085See
RUSRussia Nenet Mixed0.118055See
BRABrazil North East Mixed0.1170205See
BRABrazil Parana Caucasian23.40.11702775See
ITAItaly North Pavia0.117081See
SVKSlovakia pop 20.11674234See
INDIndia Tamil Nadu Chennai21.90.1162137See
ESPSpain Malaga21.90.1162160See
MEXMexico Veracruz, Coatzacoalcos0.116155See
SRBSerbia Vojvodina22.20.1160400See
RUSRussia Tatars0.1154355See
ITAItaly pop 421.70.11504575See
BRABrazil REDOME Amapa0.114017864See
GBRUnited Kingdom pop 20.1140101See
MEXMexico Chiapas, Tuxtla Gutierrez0.113252See
GRCGreece North0.1130500See
ECUEcuador Coast Mixed Ancestry0.1113238See
ALBAlbania pop 221.10.1111432See
BRABrazil Parana Cafuzo22.20.1110319See
BRABrazil REDOME Amazonas0.110724129See
GBRUnited Kingdom Central0.1090135See
GBRUnited Kingdom South West0.1090163See
ARMArmenia Yerevan0.1090445See
RUSRussia Arkhangelsk Pomor0.109063See
IRNIran pop 40.1085855See
UKRUkraine Lvov0.1080102See
KORSouth Korea pop 80.10707096See
ITAItaly South Campania Region20.20.10661089See
ENGEngland Newcastle20.20.10662739See
MEXMexico Colima, Colima city0.106661See
ROMRomania pop 320.60.10621469See
GBRUnited Kingdom renal patients19.90.10607007See
RUSRussia Smolensk0.1060156See
BRABrazil Parana Oriental21.20.106033See
AUSAustralia South and East Caucasian20.00.10551210See
ITAItaly Central0.1050380See
BIHBosnia and Herzegovina0.1044134See
RUSRussia Mari0.1040202See
RUSRussia Kostroma Region0.1040126See
ARGArgentina Cuyo Region19.80.1040420See
ENGEngland Lancaster19.60.1033545See
ARGArgentina Buenos Aires pop 219.00.10301216See
MEXMexico Colima Rural0.102343See
MKDMacedonia MBMDR - Macedonian19.30.10131283See
GBRUnited Kingdom East0.1006163See
BLRBelarus Gomel Region0.1000100See
VENVenezuela Zulia San Jose de Heras Mixed0.100020See
PAKPakistan Mixed Pathan0.1000100See
MEXMexico Jalisco, Tonala0.100035See
ENGEngland Leeds18.90.09945024See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.099096See
GRCGreece pop 50.0990500See
COLColombia Antioquia Paisa0.0990100See
ESPSpain Majorca0.0990407See
AUSAustralia West Caucasian18.70.0990891See
RUSRussia Arkhangelsk0.099081See
ESPSpain Majorcans Jews0.0980103See
HRVCroatia pop 20.0980100See
MEXMexico Nayarit, Tepic0.097997See
IRNIran Royan Cord Blood Bank18.50.097015600See
WALWales pop 218.50.097039979See
ARGArgentina Corrientes18.70.0970155See
FRAFrance West Breton0.0960150See
MEXMexico Coahuila, Saltillo0.095972See
ENGEngland Sheffield18.20.09554755See
ENGEngland Liverpool18.10.09501343See
MEXMexico Mexico City Mestizo0.0950121See
IRQIraq Erbil18.80.0942372See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks17.90.0940112See
MEXMexico Nayarit Rural0.093864See
KURIraq Kurdistan Region17.20.0930209See
BRABrazil Curitiba-Parana Mixed0.0928264See
POLPoland Lodz0.0920103See
RUSRussia Murmansk Saomi Mixed0.092070See
ENGEngland Manchester17.50.09171640See
MEXMexico Durango Rural0.0917326See
MEXMexico Mestizo pop 40.0911269See
GRCGreece pop 70.090511250See
MEXMexico Zacatecas, Fresnillo0.0905103See
GBRUnited Kingdom North0.0902330See
TTOTrinidad South Asian0.090087See
TURTurkey Ankara0.090050See
ENGEngland North West Mixed pop 217.70.0897379See
MEXMexico Jalisco, Zapopan0.0893168See
ARMArmenia living in Karabakh0.0890445See
IRLIreland South pop 20.088417624See
MEXMexico Sinaloa, Culiacán0.0874103See
ARMArmenia living in Lebanon0.0870368See
IRLIreland Donegal16.50.0870200See
ARMArmenia Shirak0.086076See
GBRUnited Kingdom Orkney0.085988See
ARMArmenia Ghegharkunik0.0830242See
MEXMexico Sonora Rural0.0812197See
MEXMexico Jalisco Rural0.0811585See
MEXMexico Chihuahua Chihuahua City0.0798119See
MEXMexico Jalisco, Guadalajara city0.07831189See
IRLIreland Wexford14.50.0780200See
ESPSpain North15.00.0780156See
JPNJapan pop 100.0780332See
ARMArmenia Syunik0.0770117See
SDNSudan East Rashaida14.80.076927See
MEXMexico Jalisco, Tlaquepaque0.076939See
MEXMexico Sinaloa Rural0.0765183See
MEXMexico Oaxaca, Oaxaca city0.0762151See
MEXMexico Zacatecas Rural0.0762266See
MEXMexico Michoacan Rural0.0759348See
MEXMexico Tamaulipas Rural0.0754125See
CHNChina Shandong Province14.50.07507418See
MEXMexico Chihuahua, Ciudad Juarez0.0741106See
MEXMexico Aguascalientes state0.073795See
MEXMexico Chihuahua Rural0.0732236See
MEXMexico Tabasco, Villahermosa0.073282See
MEXMexico Morelos, Cuernavaca0.073282See
BRABrazil Southeast Campinas Mixed14.10.073199See
CUBCuba Mixed pop 20.0700189See
MEXMexico Baja Californa, Mexicali0.0700100See
MEXMexico Queretaro Rural0.069843See
ESPSpain Ibiza0.069088See
MEXMexico Guanajuato, Guanajuato city0.068222See
GEOGeorgia Kurds0.067030See
MEXMexico Puebla Mestizo0.066099See
CHNChina Jiangsu Province0.066020248See
ECUEcuador Mixed Ancestry0.06561173See
MEXMexico Tamaulipas, Ciudad Victoria0.065223See
CZECzech Republic Gypsy pop 213.00.065246See
MEXMexico Coahuila Rural0.0642216See
PERPeru Arequipa Mestizo12.30.0630168See
TWNTaiwan Chinese immigrants from North China0.0630152See
TURTurkey pop 20.0620228See
MEXMexico Mexico City Center0.0617152See
MEXMexico Hidalgo, Pachuca0.061041See
AREUnited Arab Emirates pop 211.80.0610373See
VNMVietnam Hanoi0.060050See
MEXMexico Coahuila, Torreon0.0600396See
MEXMexico Guerrero state0.0590144See
MEXMexico Nuevo Leon Rural0.0580439See
CHNChina Guangdong Province11.20.0576403See
MEXMexico San Luis Potosi Rural0.057587See
MEXMexico Veracruz Rural0.0573539See
MEXMexico Tabasco Rural0.0563142See
MEXMexico Yucatan Rural0.0560132See
MEXMexico Guadalajara Mestizo0.056054See
CHNChina Shaanxi Province Han0.056010000See
MEXMexico Hidalgo Rural0.055681See
ECUEcuador Andes Mixed Ancestry0.0546824See
CHNChina Han10.50.0539314See
MEXMexico Veracruz, Cordoba0.053656See
MEXMexico Zacatecas, Zacatecas city0.053684See
MEXMexico Michoacan, Morelia0.0530150See
MEXMexico Guanajuato Rural0.0521162See
MEXMexico Durango, Durango city0.0516153See
MEXMexico Nuevo Leon, Monterrey city0.0509226See
MEXMexico Sonora, Hermosillo0.050599See
MYSMalaysia pop 20.050062See
MEXMexico Oaxaca Rural0.0483485See
MEXMexico Mexico City South0.048152See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.048094See
MEXMexico Veracruz, Veracruz city0.0465171See
CHNChina Shanghai0.046026266See
CHNChina Beijing and Guangzhou0.04601592See
ITAItaly Sardinia0.046086See
MEXMexico Sonora, Ciudad Obregón0.0455143See
IRNIran Baloch0.0450100See
MYSMalaysia pop 30.04301445See
BGDBangladesh Dhaka Bangalee0.0420141See
MEXMexico Tlaxcala Rural0.0410830See
MEXMexico Baja California, Tijuana0.040025See
MEXMexico mestizo pop 30.0398201See
MEXMexico Mexico City Metropolitan Area Rural0.0395150See
MKDMacedonia MBMDR - Macedonian Muslims7.90.039576See
TWNTaiwan Chinese immigrants from Middle China0.0380211See
TWNTaiwan Hakka pop 20.0380714See
TWNTaiwan Minnan pop 20.03707137See
CHNChina Shandong Province Linqu County7.20.0366139See
MEXMexico Puebla, Puebla city0.03661994See
ESPSpain Andalusia Gipsy0.036099See
THAThailand pop 40.036016807See
MEXMexico Tlaxcala, Tlaxcala city0.0359181See
MEXMexico Yucatan, Merida0.0359192See
PAKPakistan Brahui0.0350104See
MEXMexico Veracruz, Xalapa0.0348187See
MEXMexico Veracruz, Poza Rica0.033345See
MMRMyanmar Bamar6.50.032647See
ESPSpain Malaga Gypsy6.30.032080See
MEXMexico Campeche Rural0.031947See
MEXMexico Mexico City East0.031379See
MEXMexico Quintana Roo Rural0.030050See
MEXMexico Puebla Rural0.0300833See
MEXMexico Campeche, Campeche city0.029434See
MEXMexico Mexico City West0.029433See
MEXMexico Mexico City North0.0286751See
THAThailand pop 20.0280124See
PAKPakistan Baloch0.028066See
ECUEcuador Amazonia Mixed Ancestry0.025639See
MEXMexico Guanajuato, Leon0.025678See
CHLChile Huilliche0.025040See
BORBorneo Bandjarmasin0.024021See
WSMSamoa West0.023022See
TWNTaiwan Chinese immigrants from South China0.0230172See
MEXMexico Queretaro, Queretaro city0.022245See
MEXMexico Quintana Roo, Cancun0.020848See
MEXMexico Chiapas Rural0.0207121See
COLColombia Guajira Peninsula Wayuu0.018088See
IDNIndonesia Java0.017058See
MEXMexico Morelos Rural0.016730See
MEXMexico San Luis Potosi, San Luis Potosi city0.016730See
COLColombia Sierra Nevada de Santa Marta Arhuaco0.0160107See
COLColombia Bogota and Medellin Mestizo0.015065See
CODCongo Kinshasa expatriates living in Belgium2.30.013075See
MMRMyanmar Kayah1.80.009155See
ITAItaly Sardinia pop21.80.00901129See
MEXMexico Veracruz, Orizaba0.008360See
MMRMyanmar Mon1.60.007864See
TWNTaiwan Aborigine0.0050111See
BRABrazil Kaingang0.0020235See
MEXMexico Huasteca Region Teenek0.000055See
BRABrazil Guarani M bya0.000093See
ARGArgentina Salta Wichi pop 20.00.000019See
PNGPapua New Guinea Lowland Roro0.000026See
PNGPapua New Guinea Trobriand Island0.000081See
ARGArgentina Kolla0.000061See
PNGPapua New Guinea East New Britain Tolai0.000048See
PNGPapua New Guinea Highland pop20.000028See
TWNTaiwan Aborigine pop 20.000048See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
MYSMalaysia Perak Rawa0.000023See
MEXMexico Baja California Rural0.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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