Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.

   

A*02:22

Allele reported 120 time(s) and present in 61 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
CRICosta Rica Guaymi NA-DHS_10 (G)83.30.444418See
COLColombia Wayuu NA-DHS_15 (G)33.30.166715See
COLColombia Zenu NA-DHS_18 (G)33.30.166716See
BRABrazil Terena25.00.150060See
COLColombia Arhuaco NA-DHS_16 (G)23.50.117617See
VENVenezuela Perja Mountain Bari0.091055See
USAUSA NMDP Black South or Central American0.08454889See
INDIndia West Bhil0.080050See
BOLBolivia/Chile Aymara NA-DHS_13 (G)10.00.050020See
COLColombia Bogotá Cord Blood6.40.03211463See
BOLBolivia/Peru Quechua NA-DHS_12 (G)4.80.023821See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0130146See
INDIndia New Delhi0.008071See
MNGMongolia Buryat0.0070141See
PANPanama0.0068462See
NICNicaragua Managua1.20.0060339See
USAUSA NMDP Hispanic South or Central American0.0056146714See
SGPSingapore Thai0.0050100See
CHLChile Santiago Mixed1.00.005070See
CHNChina Qinghai Province Hui0.0050110See
CHNChina Guangdong Province Meizhou Han0.0050100See
USAUSA San Antonio Caucasian0.0030222See
AREUnited Arab Emirates Pop 10.0030570See
USAUSA Spain Ancestry0.0020279See
USAUSA Hispanic pop 20.00201999See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
USAUSA Caucasian pop 40.00191070See
MYSMalaysia Peninsular Indian0.40.0018271See
MYSMalaysia Peninsular Malay0.30.0016951See
TZATanzania Maasai0.30.0015336See
USAUSA NMDP Caribean Hispanic0.0014115374See
USAUSA NMDP Caribean Indian0.001014339See
ITAItaly pop 50.0010975See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
USAUSA Mexican American Mestizo0.0010553See
USAUSA African American pop 30.0010564See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.20.00084335See
USAUSA NMDP African0.000828557See
DEUGermany DKMS - Croatia minority0.00072057See
ISRIsrael Ethiopia Jews0.00045928See
DEUGermany DKMS - Portugal minority0.00041176See
DEUGermany DKMS - Spain minority0.00051107See
USAUSA NMDP Mexican or Chicano0.0002261235See
USAUSA NMDP Caribean Black0.000233328See
DEUGermany DKMS - Turkey minority0.00024856See
HRVCroatia pop 40.00024000See
POLPoland DKMS0.000320653See
USAUSA African American pop 40.00022411See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000270890See
DEUGermany DKMS - German donors0.00023456066See
DEUGermany pop 80.000139689See
USAUSA NMDP Hawaiian or other Pacific Islander0.000111499See
USAUSA NMDP North American Amerindian0.000135791See
USAUSA NMDP African American pop 20.0001416581See
USAUSA NMDP European Caucasian0.00011242890See
USAUSA NMDP Southeast Asian0.000027978See
USAUSA NMDP Chinese0.000099672See
ISRIsrael Libya Jews0.00003739See
ISRIsrael Argentina Jews0.00004307See
USAUSA NMDP Korean0.000077584See
USAUSA NMDP South Asian Indian0.0000185391See
NLDNetherlands Leiden0.00001305See
USAUSA Asian pop 20.00001772See
CHNChina Tibet Region Tibetan0.0000158See
DEUGermany pop 60.00018862See
CHNChina Inner Mongolia Region0.0000102See
KORSouth Korea pop 30.0000485See
USAUSA Philadelphia Caucasian0.00.0000141See
CHNChina North Han0.0000105See
PAKPakistan Karachi Parsi0.000091See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
HKGHong Kong Chinese0.00.0000569See
BGRBulgaria0.000055See
HRVCroatia0.0000150See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
USAUSA Caucasian0.00.000061655See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
CZECzech Republic0.0000106See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
ROMRomania0.00.0000348See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
TURTurkey pop 50.0000142See
USAUSA Caucasian pop 30.000088See
USAUSA African American pop 20.0000149See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
MEXMexico Mestizo0.00.000041See
OMNOman0.00.0000118See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
NIRIreland Northern0.00.00001000See
INDIndia West Coast Parsi0.000050See

See also higher resolution data of this allele


Allele  Number of Populations 
 A*02:22:01 10 
 A*02:22:02 
 A*02:220 
 A*02:221 
 A*02:223N 
 A*02:224 
 A*02:226N 
 A*02:227N 
 A*02:229 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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