Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.

   

B*52

Allele reported 409 time(s) and present in 392 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
INDIndia Kerala Paniya0.350010See
INDIndia Kerala Kattunaikka0.265017See
INDIndia Kerala Adiya0.214021See
MMRMyanmar Rakhine29.20.166748See
JPNJapan pop 1125.80.138662See
MMRMyanmar Kachin22.20.127063See
MMRMyanmar Chin23.60.118255See
JPNJapan Kyoto and Osaka0.1180165See
JPNJapan Aichi17.40.109050See
MEXMexico San Vicente Tancuayalab Teenek/Huastecos0.103853See
MEXMexico Huasteca Region Teenek0.102055See
JPNJapan Tohoku Region0.1000322See
INDIndia North pop 30.0980587See
MMRMyanmar Bamar19.60.097846See
MEXMexico Nahuas0.097072See
GHAGhana Accre Asutuare Akan0.0940429See
JPNJapan pop 20.0920916See
JPNJapan Hyogo Osaka and Nagano0.0920195See
TTOTrinidad South Asian0.090087See
ISRIsrael Moroccan Jews0.0880113See
MYSMalaysia Sarawak Iban0.088051See
MEXMexico Jalisco, Tonala0.085735See
BGDBangladesh Dhaka Bangalee0.0850141See
PAKPakistan Mixed Sindhi0.0840101See
SDNSudan Khartoum0.081798See
MEXMexico Baja California, La Paz0.073375See
INDIndia Kerala Hindu Nair0.073041See
BRABrazil Parana Japanese13.00.0729192See
IRQIraq Erbil14.50.0727372See
MNGMongolia Tarialan Khoton0.071085See
PAKPakistan Burusho0.071092See
INDIndia North Gujarat13.90.0710338See
CHNChina Yunnan Province Naxi0.0670118See
JPNJapan Hyogo12.50.063032See
MMRMyanmar Mon12.50.062564See
ITAItaly East Sicily12.00.060050See
KURIraq Kurdistan Region11.00.0600209See
MEXMexico Sonora, Ciudad Obregón0.0594143See
IRNIran pop 40.0556855See
MMRMyanmar Kayah10.90.054555See
IRNIran Royan Cord Blood Bank10.50.054015600See
MEXMexico Veracruz, Xalapa0.0535187See
AREUnited Arab Emirates pop 210.20.0520373See
MEXMexico Jalisco, Tlaquepaque0.051339See
MEXMexico Baja California Rural0.050050See
VENVenezuela Zulia Maracaibo Mixed0.050020See
ISRIsrael Jews pop 29.90.050023000See
INDIndia Kerala Malapandaram0.050010See
PAKPakistan Karachi Parsi0.049091See
LKASri Lanka Colombo Sinhalese0.0490101See
MNGMongolia Tsaatan0.0490144See
ARMArmenia living in Karabakh0.0490445See
CHNChina Shandong Province Linqu County9.40.0481139See
MEXMexico Mexico City South0.048152See
CHNChina Harbin Manchu0.0460172See
ESPSpain Arratia Valley Basque0.046083See
JORJordan0.046015141See
MMRMyanmar Kayin9.10.045544See
MEXMexico Sonora, Hermosillo0.045599See
BRABrazil Parana Oriental9.10.045033See
INDIndia Kerala Kanikkar0.045022See
MEXMexico Mexico City West0.044833See
MEXMexico Veracruz, Poza Rica0.044445See
MEXMexico Queretaro, Queretaro city0.044445See
MEXMexico Tlaxcala, Tlaxcala city0.0442181See
ECUEcuador Coast Mixed Ancestry0.0441238See
MEXMexico Sinaloa Rural0.0437183See
MEXMexico Veracruz Rural0.0434539See
MEXMexico Mexico City Metropolitan Area Rural0.0428150See
MEXMexico Tlaxcala Rural0.0428830See
ENGEngland London Ashkenazi Jews0.0420500See
CZECzech Republic Kurd8.10.040574See
MYSMalaysia Perak Rawa0.040023See
MYSMalaysia Sarawak Bidayuh0.040050See
MYSMalaysia pop 20.040062See
ROMRomania pop 20.04006936See
VENVenezuela Caracas Mestizo0.040050See
MEXMexico Baja California, Tijuana0.040025See
INDIndia Bikaner Non-Raikas7.80.0400127See
MEXMexico Durango Rural0.0398326See
BRABrazil REDOME Amazonas0.039324129See
MNGMongolia Oold0.0390104See
MEXMexico Coahuila Rural0.0390216See
INDIndia Bikaner Raikas7.60.0390143See
BRABrazil REDOME Amapa0.038917864See
MEXMexico Coahuila, Torreon0.0388396See
ARMArmenia Syunik0.0380117See
ESPSpain Majorcans Jews0.0380103See
INDIndia Kerala Hindu Namboothiri0.038040See
MNGMongolia Ulaanbaatar Khalkha0.037041See
MARMorocco0.037096See
ARMArmenia Yerevan0.0370445See
MMRMyanmar Shan7.40.037054See
MEXMexico Hidalgo, Pachuca0.036641See
ROMRomania pop 37.10.03621469See
GEOGeorgia Kurds0.036030See
MEXMexico Veracruz, Coatzacoalcos0.035755See
BRABrazil Para Cord Blood Unit7.10.0357841See
MEXMexico Puebla Rural0.0354833See
CHNChina Shaanxi Province Han0.035010000See
TURTurkey pop 50.0350142See
MYSMalaysia pop 30.03501445See
MEXMexico Mexico City North0.0345751See
MEXMexico Colima Rural0.034143See
BRABrazil REDOME Para0.033472637See
MEXMexico San Luis Potosi, San Luis Potosi city0.033330See
MEXMexico Jalisco, Tlajomulco0.033330See
MEXMexico Veracruz, Orizaba0.033360See
MEXMexico Oaxaca, Oaxaca city0.0331151See
ARMArmenia Shirak0.033076See
CHNChina Shandong Province6.60.03307418See
INDIndia Kerala Kuruma0.033015See
MEXMexico Colima, Colima city0.032861See
MEXMexico Chihuahua, Ciudad Juarez0.0324106See
MEXMexico Veracruz, Veracruz city0.0320171See
ISRIsrael Ashkenazi Jews pop 20.0320132See
CHNChina Yunnan Province Han pop 20.0320129See
GRCGreece Crete0.0320135See
ROMRomania6.30.0320348See
MEXMexico Nuevo Leon Rural0.0318439See
MEXMexico Tamaulipas Rural0.0317125See
MEXMexico Jalisco Rural0.0316585See
MEXMexico Nayarit Rural0.031364See
BRABrazil REDOME Roraima0.03134140See
ARMArmenia living in Lebanon0.0310368See
ALBAlbania0.0310160See
RUSRussia Moscow0.03102650See
BRABrazil Parana Cafuzo6.30.0310319See
CHNChina Jiangsu Province0.031020248See
MEXMexico Nuevo Leon, Monterrey city0.0310226See
MEXMexico Hidalgo Rural0.030981See
MEXMexico Morelos, Cuernavaca0.030582See
PAKPakistan Mixed Pathan0.0300100See
VNMVietnam Hanoi0.030050See
BIHBosnia and Herzegovina0.0298134See
MEXMexico Campeche, Campeche city0.029434See
MEXMexico Chihuahua Rural0.0293236See
GRCGreece pop 70.029111250See
ARMArmenia Ghegharkunik0.0290242See
INDIndia Kerala Malabar Muslim0.029034See
MEXMexico Durango, Durango city0.0290153See
BRABrazil Para State5.60.02805000See
ARMArmenia living in USA0.0280233See
SRBSerbia Vojvodina5.70.0280400See
MEXMexico Guanajuato Rural0.0276162See
MEXMexico Coahuila, Saltillo0.027472See
MEXMexico Puebla, Puebla city0.02731994See
MEXMexico Mexico City Mestizo pop 30.0270256See
RUSRussia South Ural Russian5.30.0270207See
MEXMexico Sinaloa Mestizo0.027056See
KORSouth Korea pop 80.02707096See
CHNChina Shanghai0.027026266See
IRQIraq Arabs5.40.0268149See
MEXMexico Michoacan, Morelia0.0265150See
ENGEngland North West Mixed pop 25.30.0264379See
MKDMacedonia MBMDR - Macedonian Muslims5.30.026376See
MEXMexico Aguascalientes state0.026395See
MEXMexico Zacatecas Rural0.0260266See
RUSRussia South Ural Tatar4.40.0260135See
MEXMexico Mestizo pop 40.0260269See
ARGArgentina Salta Wichi pop 25.30.026019See
MEXMexico Oaxaca Rural0.0257485See
ALBAlbania pop 25.10.0255432See
RUSRussia Tatars0.0253355See
DZAAlgeria pop 25.00.0253106See
BRABrazil Pernambuco Mixed0.0250101See
VENVenezuela Zulia San Jose de Heras Mixed0.025020See
USAUSA OPTN Hispanic0.02501580See
MNGMongolia Khalkha0.0250200See
BRABrazil Sao Paulo Mixed0.50.0250239See
KORSouth Korea pop 10.0250324See
TUNTunisia5.00.0250100See
BRABrazil Belem Mixed5.00.0250100See
MEXMexico Chiapas Rural0.0248121See
ECUEcuador Mixed Ancestry0.02471173See
MEXMexico Tabasco Rural0.0246142See
ITAItaly pop 64.90.0245184See
RUSRussia Moscow Pop 24.70.02442000See
MEXMexico Tabasco, Villahermosa0.024482See
MEXMexico Sinaloa, Culiacán0.0243103See
ESPSpain Murcia0.0240173See
USAUSA OPTN Asian0.0240261See
MEXMexico Jalisco, Zapopan0.0238168See
VENVenezuela Colonia Tovar0.023386See
MKDMacedonia pop 30.0230172See
MKDMacedonia pop 40.0230216See
PAKPakistan Baloch0.023066See
MARMorocco pop 20.0230110See
THAThailand pop 40.023016807See
PRTMadeira pop 20.0230173See
MEXMexico Michoacan Rural0.0229348See
BRABrazil REDOME Maranhao0.022710180See
GBRUnited Kingdom South West0.0225163See
MEXMexico Yucatan Rural0.0224132See
INDIndia sub-Himalayan West Bengal Kami4.40.0222158See
BRABrazil REDOME Parana0.0221341639See
SAUSaudi Arabia pop 44.00.0221499See
BRABrazil REDOME Mato Grosso0.022034649See
CHNChina Harbin Korean0.0220201See
CZECzech Republic Romani pop 24.40.021746See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
CHNChina Guangdong Province4.20.0212403See
BRABrazil REDOME Mato Grosso do Sul0.021195667See
RUSRussia Samara Region0.02102500See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.021094See
BRABrazil Parana Mixed race4.30.0210186See
CHNChina Wuhan4.10.0210121See
MEXMexico Tapachula, Chiapas Mestizo Population4.20.021072See
ALBAlbanian Kosovo0.0208120See
BRABrazil Curitiba-Parana Mixed0.0206264See
MEXMexico Yucatan, Merida0.0205192See
BRABrazil REDOME Alagoas0.020225349See
BRABrazil REDOME Piaui0.020146140See
ARMArmenia Lori0.0200102See
BRABrazil Rio Grande do Sul Black0.0200248See
BRABrazil Rio Grande do Norte Mestizo0.020012973See
BRABrazil Piaui Mixed0.020021943See
MTQMartinique0.0200100See
ITAItaly Rome4.00.0200100See
ARGArgentina Buenos Aires4.10.0200466See
RUSRussia Arkhangelsk Pomor0.020063See
TTOTrinidad African0.020067See
TWNTaiwan Chinese immigrants from North China0.0200152See
MNGMongolia Khalkha pop 20.0200202See
HRVCroatia pop 20.0200100See
MEXMexico Quintana Roo Rural0.020050See
BRABrazil South East Cord Blood0.020011409See
BRABrazil REDOME Rio Grande do Norte0.019946603See
MKDMacedonia MBMDR - Macedonian4.00.01991283See
BRABrazil REDOME Rondonia0.019854396See
BRABrazil REDOME Tocantins0.019720692See
BRABrazil REDOME Ceara0.0197101217See
ITAItaly North Pavia pop 30.0197685See
BRABrazil REDOME Sao Paulo0.0196800809See
BRABrazil REDOME Sergipe0.01937321See
MEXMexico Jalisco, Guadalajara city0.01931189See
MEXMexico Guanajuato, Leon0.019278See
CHLChile Santiago0.0190920See
BRABrazil Sao Paulo Bauru Mixed0.01903542See
SRBSerbia0.0190386See
BRABrazil Parana Afro Brazilian3.90.019077See
BRABrazil Parana Caucasian3.80.01902775See
RUSRussia Sakhalin Island Nivkhi0.019053See
ESPSpain North Cabuerniga0.019095See
BRABrazil REDOME Federal District0.018829549See
BRABrazil REDOME Goias0.018688574See
BRABrazil REDOME Bahia0.018547399See
BRABrazil REDOME Pernambuco0.018492332See
ECUEcuador Andes Mixed Ancestry0.0182824See
BRABrazil REDOME Espirito Santo0.018188485See
RUSRussia Northwest3.60.01811011See
ITAItaly South Campania Region3.60.01811089See
GRCGreece North0.0180500See
RUSRussia Northwest pop 23.60.0180346See
MEXMexico Veracruz, Cordoba0.017956See
MEXMexico Zacatecas, Zacatecas city0.017984See
MEXMexico Sonora Rural0.0178197See
MKDMacedonia0.0175286See
MEXMexico Guerrero state0.0174144See
BRABrazil REDOME Paraiba0.017443868See
NGANigeria3.50.0174258See
RUSRussia South Ural Bashkir3.40.0170146See
MEXMexico Mexico City Mestizo0.0170121See
TWNTaiwan Chinese immigrants from Middle China0.0170211See
TURTurkey pop 20.0170228See
BRABrazil Minas Gerais State Mixed3.20.01701000See
POLPoland pop 33.40.01692907See
MEXMexico Chihuahua Chihuahua City0.0168119See
HRVCroatia pop 33.30.0167120See
SVKSlovakia pop 20.01664234See
BRABrazil Paraná Caucasian3.10.0164641See
BRABrazil REDOME Acre0.0163859See
BRABrazil REDOME Minas Gerais0.0160211275See
BRABrazil Rio Grande do Sul Caucasoid0.01604428See
BRABrazil Rio Grande do Sul Mixed0.0160324See
IRNIran pop 10.016064See
BRABrazil South Ribeirao Preto0.0160184See
ITAItaly North Pavia pop 23.20.01602416See
SAUSaudi Arabia pop 20.0160383See
INDIndia Kerala Syrian Christian0.016031See
USAUSA African American Bethesda3.20.0160187See
COLColombia Barranquilla0.0160188See
GTMGuatemala, Guatemala City Mixed Ancestry3.20.0157127See
MEXMexico Nayarit, Tepic0.015597See
BRABrazil REDOME Rio de Janeiro0.0153139322See
BRABrazil REDOME Santa Catarina0.0150106673See
GAZGaza Palestinians0.0150165See
RUSRussia Northwest pop 33.00.0150100See
MEXMexico Baja Californa, Mexicali0.0150100See
BRABrazil REDOME Rio Grande do Sul0.0147241329See
ESPSpain Sevilla2.90.0144278See
MEXMexico Zacatecas, Fresnillo0.0143103See
PAKPakistan Brahui0.0140104See
ITAItaly0.0140159311See
USAUSA OPTN African American0.01401510See
ESPSpain, Castilla y Leon, Northwest,2.70.01391743See
RUSRussia Transbaikal Territory Buryats3.00.0130150See
ITAItaly Lombardy2.70.0130674See
ARGArgentina Cuyo Region2.60.0130420See
SENSenegal Dakar2.70.0130112See
ARGArgentina Corrientes2.60.0130155See
PRTPortugal Beja0.0130699See
ECUEcuador Amazonia Mixed Ancestry0.012839See
COLColombia San Basilio de Palenque0.012042See
GBRUnited Kingdom Orkney0.012088See
FRAFrance Southeast2.30.0120130See
PERPeru Lamas City Lama0.012083See
ARGArgentina Buenos Aires pop 22.40.01201216See
GRCGreece pop32.40.0120246See
SRBSerbia pop 32.20.01181992See
PRTPortugal Aveiro0.01105933See
PRTPortugal Setubal0.01105268See
PRTPortugal Lisbon0.011017420See
ESPSpain Minorca0.011094See
FRAFrance Marseille2.20.01081000See
GBRUnited Kingdom North0.0108330See
MEXMexico Campeche Rural0.010647See
MEXMexico Quintana Roo, Cancun0.010448See
PHLPhilippines National Capital Region0.010051See
MEXMexico Puebla Mestizo0.010099See
PRTPortugal Portalegre0.01001254See
PRTPortugal Leiria0.01001847See
PRTPortugal Faro0.01001242See
MYSMalaysia Negeri Sembilan Minangkabau0.010034See
RUSRussia Murmansk Saomi Mixed0.010070See
FRAFrance Reims0.0100102See
ESPSpain North2.00.0100156See
FRAFrance Lyon2.00.00994813See
FRAFrance Grenoble2.00.00981000See
MEXMexico Mexico City Center0.0097152See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks1.80.0090112See
PRTPortugal Braga0.00901971See
PRTPortugal Castelo Branco0.0090327See
PRTPortugal Coimbra0.00905057See
PRTPortugal Santarem0.00903865See
DEUGermany1.80.009011407See
ARGArgentina Chiriguano1.90.009054See
SWESweden pop 41.70.0088966See
MEXMexico Sinaloa Capomos Mayo Yoremes0.008360See
BIHBosnia and Herzegovina pop 21.70.0083120See
SVNSlovenia pop 31.50.0080130See
PRTPortugal Evora0.0080737See
PRTPortugal Viseu0.00802915See
TWNTaiwan Hakka pop 20.0080714See
TWNTaiwan Minnan pop 20.00807137See
CUBCuba Mixed pop 20.0080189See
PRTPortugal South pop 20.00801021See
FRAFrance Bordeaux1.60.0078990See
GBRUnited Kingdom Central0.0075135See
PRTPortugal Porto0.00707937See
CUBCuba Mixed0.007078See
USAUSA OPTN Caucasian0.00708525See
PERPeru Arequipa Mestizo1.40.0070168See
MEXMexico Mayan Pop 30.007066See
AUSAustralia West Caucasian1.50.0070891See
PAKPakistan Kalash0.007069See
FRAFrance Rennes pop 41.40.00671000See
MEXMexico Mexico City East0.006379See
PRTPortugal Vila Real0.00601167See
PRTMadeira pop 30.0060538See
DEUGermany Essen1.20.0060174See
ESPSpain Ibiza0.006088See
ESPSpain North Cantabria0.006083See
PRTPortugal Center pop 20.0060562See
FRAFrance Grenoble, Nantes and Rennes0.00606094See
MEXMexico San Luis Potosi Rural0.005787See
ENGEngland Newcastle1.10.00552739See
ENGEngland Manchester1.00.00501640See
GBRUnited Kingdom pop 20.0050101See
TWNTaiwan Minnan and Hakka0.0050190See
WALWales pop 21.00.005039979See
PRTPortugal Viana do Castelo0.0050706See
PRTPortugal Bragança0.0050301See
FRAFrance Rennes pop 30.0050200See
MOZMozambique0.0050202See
ENGEngland Sheffield0.90.00454755See
ENGEngland Leeds0.80.00405024See
WALWales0.90.00401798See
PRTAzores0.00401050See
MKDMacedonia MBMDR - Albanian0.80.0039128See
PRTPortugal North pop 20.00371801See
GBRUnited Kingdom East0.0031163See
IRLIreland South pop 20.003017624See
PRTPortugal Guarda0.0030797See
TWNTaiwan Chinese immigrants from South China0.0030172See
ESPSpain Majorca0.0030407See
NORNorway ethnic Norwegians0.50.00244510See
ENGEngland Liverpool0.40.00201343See
SWESweden Uppsala0.30.0015300See
ENGEngland Lancaster0.20.0010545See
USAUSA NMDP Black South or Central American0.00014889See
TZATanzania Dodoma Kongwa0.0000212See
CHNChina North Han0.0000105See
SAUSaudi Arabia0.00.000018See
INDIndia Kerala Hindu Pulaya0.000016See
INDIndia Kerala Hindu Ezhava0.000024See
INDIndia Kerala Kurichiya0.000010See
USAUSA Caucasian Bethesda0.00.0000307See
TWNTaiwan Aborigine0.0000111See
PRTPortugal North0.000046See
ARGArgentina La Plata0.00.0000100See
RUSRussia Nenet Mixed0.000055See
SCOScotland Orkney0.00.000099See
ZAFSouth Africa Natal Zulu0.00.0000100See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Morelos Rural0.000030See
MEXMexico Queretaro Rural0.000043See

See also higher resolution data of this allele


Allele  Number of Populations 
 B*52:01 235 
 B*52:01:01 103 
 B*52:01:01:01 
 B*52:01:01:02 
 B*52:01:02 61 
 B*52:01:02:01 
 B*52:01:03 
 B*52:01:04 
 B*52:01:05 
 B*52:01:06 
 B*52:01:10 
 B*52:01:11 
 B*52:01:29 
 B*52:02 27 
 B*52:03 18 
 B*52:04 35 
 B*52:05 24 
 B*52:06 10 
 B*52:06:01 
 B*52:06:02 
 B*52:07 
 B*52:08 
 B*52:09 
 B*52:10 10 
 B*52:11 10 
 B*52:12 
 B*52:13 
 B*52:14 
 B*52:15 
 B*52:16 
 B*52:17 
 B*52:18 
 B*52:19 
 B*52:21:01 
 B*52:25 
 B*52:30 
 B*52:37 
 B*52:40 
 B*52:50 
 B*52:51 
 B*52:53 
 B*52:64 
 B*52:80 
 B*52:81 
 B*52:88 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

support@allelefrequencies.net


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