Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 123 time(s) and present in 72 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael YemenJews0.086215542See
INDIndia West Coast Parsi0.040050See
IRNIran Yazd0.035756See
IRNIran Gorgan0.031064See
STPSao Tome Island Angolar0.031032See
INDIndia Andhra Pradesh Golla0.0240111See
ZAFSouth Africa Natal Tamil0.020051See
USAUSA NMDP Filipino0.019250614See
STPSao Tome Island Forro0.015066See
INDIndia Tamil Nadu0.01372492See
INDIndia South UCBB2.70.013611446See
SGPSingapore SGVP. Indian INS0.013086See
MYSMalaysia Peninsular Indian2.20.0111271See
LKASri Lanka Colombo2.10.0110714See
VENVenezuela Perja Mountain Bari0.011055See
IRNIran Tabriz Azeris0.010397See
USAUSA NMDP Hawaiian or other Pacific Islander0.010211499See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0090146See
ISRIsrael Bukhara Jews0.00872317See
IRNIran Saqqez-Baneh Kurds0.008360See
IRNIran Kurd pop 20.008060See
ISRIsrael Iraq Jews0.007513270See
USAUSA NMDP South Asian Indian0.0071185391See
INDIndia East UCBB1.40.00712403See
INDIndia West UCBB1.10.00525829See
USAUSA NMDP Southeast Asian0.005027978See
USAUSA San Diego1.00.0050496See
CHNChina North Han0.0050105See
SENSenegal Niokholo Mandenka0.0050165See
SGPSingapore Riau Malay0.0050132See
ISRIsrael Kavkazi Jews0.00392840See
ISRIsrael Georgia Jews0.00354471See
INDIndia Central UCBB0.60.00324204See
RUSRussia Tuva pop 20.0030169See
ISRIsrael Ethiopia Jews0.00285928See
USAUSA Asian pop 20.00261772See
INDIndia North UCBB0.40.00215849See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
USAUSA NMDP Vietnamese0.001243540See
ISRIsrael Iran Jews0.00128153See
ISRIsrael Morocco Jews0.001136718See
ISRIsrael Ashkenazi Jews pop 30.00114625See
USAUSA NMDP Caribean Indian0.001014339See
ISRIsrael USSR Jews0.000745681See
ISRIsrael Druze0.00065914See
ISRIsrael Tunisia Jews0.00069070See
ISRIsrael Arab pop 20.000512301See
HKGHong Kong Chinese cord blood registry0.00043892See
ISRIsrael Libya Jews0.00043739See
HKGHong Kong Chinese BMDR0.00037595See
DEUGermany DKMS - China minority0.00041282See
ISRIsrael Argentina Jews0.00024307See
USAUSA Hispanic pop 20.00031999See
ISRIsrael Poland Jews0.000213871See
SAUSaudi Arabia pop 6 (G)0.000228927See
USAUSA NMDP Korean0.000277584See
ISRIsrael USA Jews0.00026058See
USAUSA NMDP Caribean Black0.000233328See
USAUSA NMDP Chinese0.000199672See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
KORSouth Korea pop 100.00014128See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
CZECzech Republic NMDR0.00015099See
USAUSA NMDP North American Amerindian0.000135791See
USAUSA NMDP Mexican or Chicano0.0001261235See
USAUSA NMDP Hispanic South or Central American0.0000146714See
USAUSA NMDP Japanese0.000024582See
USAUSA NMDP African0.000028557See
USAUSA NMDP African American pop 20.0000416581See
USAUSA NMDP European Caucasian0.00001242890See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP Caribean Hispanic0.0000115374See
SGPSingapore SGVP Malay MAS0.000089See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
USAUSA African American pop 40.00002411See
ZAFSouth Africa Natal Zulu0.00.0000100See
HKGHong Kong Chinese0.00.0000569See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina Inner Mongolia Region0.0000102See
CHNChina Qinghai Province Hui0.0000110See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
KORSouth Korea pop 30.0000485See
SGPSingapore SGVP Chinese CHS0.000096See
SGPSingapore Chinese0.00.0000149See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PHLPhilippines Ivatan0.00.000050See

See also higher resolution data of this allele

Allele  Number of Populations 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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