Allele Frequencies in World Populations

HLA Database � Population Analysis at Amino Acid Content

This analysis tool has been introduced whereby frequency data on HLA alleles can be converted to the corresponding frequency data of amino acids. This application is useful to compare the frequency of amino acids in a population to other populations, especially in the context of a disease association study. Obviously, only those populations with 4 digits minimum resolution can be used for this tool. It is thus possible, knowing the frequency of the allele in a population, to ascertain and sum the frequencies of amino acid at each of the variable positions of the HLA molecule in that population.

Instructions

Select one of the existing populations from the Allele Frequency Net Database

   or

enter your data by loading your file (Click here to see an example of how your file should be formatted)
   
   

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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