This analysis tool has been introduced whereby frequency data on HLA
alleles can be converted to the corresponding frequency data of amino acids.
This application is useful to compare the frequency of amino acids
in a population to other populations, especially in the context of a disease
association study. Obviously, only those populations with 4 digits minimum
resolution can be used for this tool. It is thus possible, knowing the frequency
of the allele in a population, to ascertain and sum the frequencies of amino
acid at each of the variable positions of the HLA molecule in that population.