Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 60 time(s) and present in 55 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia Tamil Nadu Nadar0.205061See
RUSRussian Federation Vologda Region36.10.1891119See
USAUSA San Francisco Caucasian0.1480220See
POLPoland BMR24.80.132323595See
ENGEngland Blood Donors of Mixed Ethnicity24.90.1320519See
ZAFSouth Africa Caucasians0.1200102See
CRICosta Rica Central Valley Mestizo (G)22.20.1180221See
CPVCape Verde Northwestern Islands0.113062See
BRABrazil Rio de Janeiro Parda0.1118170See
RUSRussia Belgorod region20.90.1111153See
BRABrazil Rio de Janeiro Black0.095668See
INDIndia Mumbai Maratha0.093091See
CRICosta Rica African -Caribbean (G)16.60.0880102See
USAUSA African American pop 30.0860564See
GRCGreece Athens17.20.08591888See
BRABrazil Barra Mansa Rio State Caucasian0.0827405See
BRABrazil Rio de Janeiro Caucasian0.0806521See
CMRCameroon Yaounde0.077092See
BRABrazil Barra Mansa Rio State Black0.075373See
ESPSpain, Canary Islands, Gran canaria island14.00.0698215See
INDIndia Kerala Malayalam speaking12.90.0690356See
CPVCape Verde Southeastern Islands0.065062See
ZAFSouth African Black12.70.0634142See
INDIndia Karnataka Kannada Speaking12.60.0630174See
GNBGuinea Bissau0.062065See
ZAFSouth African Mixed ancestry10.00.060050See
SAUSaudi Arabia pop 6 (G)0.059028927See
IRNIran Baloch0.0560100See
NICNicaragua Mestizo (G)11.00.0550155See
INDIndia Andhra Pradesh Telugu Speaking10.80.0538186See
MARMorocco Settat Chaouya9.40.047098See
MARMorocco Atlantic Coast Chaouya0.047098See
CHNChina Inner Mongolia Region0.0440102See
CHNChina Qinghai Province Hui0.0410110See
CRICosta Rica Guanacaste Mestizo (G)8.20.0410110See
INDIndia West Bhil0.040050See
MARMorocco Nador Metalsa pop 20.034073See
ZAFSouth African Indian population6.00.030050See
MNGMongolia Buryat0.0290141See
CHNChina North Han0.0290105See
CHNChina Tibet Region Tibetan0.0250158See
CRICosta Rica Amerindians (G)2.40.0160125See
CHNChina Zhejiang Han0.01501734See
MEXMexico Chihuahua Tarahumara0.011044See
CHNChina Jingpo Minority1.90.0100105See
HKGHong Kong Chinese HKBMDR HLA 11 loci1.80.00915266See
MEXMexico Hidalgo Mezquital Valley/ Otomi1.40.006972See
CHNChina Guizhou Province Miao pop 20.006085See
VNMVietnam Kinh1.00.0050101See
JPNJapan Okinawa Ryukyuan0.0040143See
RUSRussia Nizhny Novgorod, Russians0.80.00401510See
USAUSA Arizona Gila River Pima0.00113000See
KORSouth Korea pop 30.0000485See
INDIndia West Coast Parsi0.000050See
INDIndia Khandesh Region Pawra0.000050See
CHNChina Guizhou Province Bouyei0.0000109See
CHNChina Guizhou Province Shui0.0000153See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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