Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 71 time(s) and present in 68 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Yunnan Province Wa0.5840119See
CHNChina Jingpo Minority70.90.4850105See
CHNChina Yunnan Province Nu0.4810107See
CHNChina Yunnan Province Lisu0.4550111See
CHNChina Yunnan Province Jinuo0.3670109See
CHNChina Guangdong Province Meizhou Han0.3030100See
HKGHong Kong Chinese HKBMDR HLA 11 loci50.60.29845266See
CHNChina Zhejiang Han0.25811734See
VNMVietnam Kinh41.00.2277101See
INDIndia Khandesh Region Pawra0.210050See
ZAFSouth African Indian population28.00.170050See
INDIndia Kerala Malayalam speaking31.20.1670356See
IDNIndonesia Sundanese and Javanese0.1640201See
CHNChina North Han0.1620105See
INDIndia Andhra Pradesh Telugu Speaking29.00.1586186See
IRNIran Baloch0.1460100See
IDNIndonesia Java pop 20.139036See
CHNChina Tibet Region Tibetan0.1300158See
INDIndia Karnataka Kannada Speaking17.80.1000174See
INDIndia Tamil Nadu Nadar0.098061See
INDIndia West Coast Parsi0.090050See
MNGMongolia Buryat0.0750141See
COLColombia Inga NA-DHS_11 (G)13.30.066716See
RUSRussia Belgorod region12.40.0654153See
POLPoland BMR11.80.060823595See
BRABrazil Barra Mansa Rio State Caucasian0.0605405See
ZAFSouth African Mixed ancestry10.00.060050See
ZAFSouth Africa Caucasians0.0600102See
USAUSA Italy Ancestry0.0600273See
ESPSpain, Canary Islands, Gran canaria island10.70.0581215See
ENGEngland Blood Donors of Mixed Ethnicity11.40.0578519See
JPNJapan Okinawa Ryukyuan0.0560143See
USAUSA San Francisco Caucasian0.0550220See
BRABrazil Barra Mansa Rio State Black0.054873See
BRABrazil Rio de Janeiro Black0.051568See
BRABrazil Rio de Janeiro Caucasian0.0480521See
MARMorocco Nador Metalsa pop 20.048073See
NICNicaragua Mestizo (G)9.60.0480155See
USAUSA Mexican American Mestizo0.0420553See
COLColombia Embera NA-DHS_19 (G)7.10.035714See
SAUSaudi Arabia pop 6 (G)0.035028927See
MARMorocco Settat Chaouya6.80.034098See
MARMorocco Atlantic Coast Chaouya0.034098See
MEXMexico Guadalajara Mestizo pop 20.0340103See
CRICosta Rica Guanacaste Mestizo (G)6.40.0320110See
BRABrazil Rio de Janeiro Parda0.0265170See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
LBYLibya Cyrenaica0.0250118See
RUSRussia Bashkortostan, Bashkirs5.00.0250120See
CPVCape Verde Northwestern Islands0.024062See
CPVCape Verde Southeastern Islands0.024062See
CRICosta Rica Central Valley Mestizo (G)4.60.0230221See
USAUSA Spain Ancestry0.0220279See
RUSRussian Federation Vologda Region4.20.0210119See
SAUSaudi Arabia pop 53.20.0158158See
ZAFSouth African Black2.80.0141142See
MEXMexico Hidalgo Mezquital Valley/ Otomi2.80.013972See
USAUSA African American pop 30.0130564See
USAUSA Arizona Pima0.0120100See
USAUSA South Dakota Lakota Sioux0.0120302See
CRICosta Rica African -Caribbean (G)1.00.0050102See
CRICosta Rica Amerindians (G)0.80.0040125See
RUSRussia Bashkortostan, Tatars0.50.0026192See
USAUSA Arizona Gila River Pima0.00093000See
RUSRussia Nizhny Novgorod, Russians0.10.00071510See
KORSouth Korea pop 30.0000485See
INDIndia West Bhil0.000050See
GNBGuinea Bissau0.000065See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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