Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 113 time(s) and present in 57 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MYSMalaysia Kedah Kensiu9.50.048021See
ARGArgentina Rosario Toba3.50.017086See
CHNChina Guizhou Province Bouyei0.0160109See
GEOGeorgia Svaneti Region Svan0.013080See
SGPSingapore Riau Malay0.0120132See
INDIndia North pop 20.010072See
ASMAmerican Samoa0.010051See
VNMVietnam Kinh2.00.0099101See
MEXMexico Mexico City Tlalpan1.80.0091330See
ECUEcuador Amerindians0.007963See
CHNChina Guizhou Province Shui0.0070153See
CHNChina Guizhou Province Miao pop 20.006085See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0040146See
MYSMalaysia Peninsular Malay0.60.0032951See
IDNIndonesia Sundanese and Javanese0.0030201See
VNMVietnam Hanoi Kinh pop 20.0030170See
ISRIsrael Ashkenazi Jews pop 30.00294625See
USAUSA NMDP Vietnamese0.002343540See
ISRIsrael Libya Jews0.00213739See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
ISRIsrael Iraq Jews0.001413270See
ISRIsrael Tunisia Jews0.00129070See
ISRIsrael Argentina Jews0.00094307See
ISRIsrael YemenJews0.000815542See
ISRIsrael USSR Jews0.000545681See
INDIndia Tamil Nadu0.00042492See
ISRIsrael Morocco Jews0.000436718See
DEUGermany DKMS - Spain minority0.00051107See
ISRIsrael Iran Jews0.00038153See
USAUSA NMDP Filipino0.000350614See
DEUGermany DKMS - China minority0.00041282See
USAUSA NMDP Southeast Asian0.000327978See
ISRIsrael Bukhara Jews0.00032317See
ISRIsrael Kavkazi Jews0.00022840See
ISRIsrael Druze0.00025914See
USAUSA Hispanic pop 20.00031999See
ISRIsrael Poland Jews0.000213871See
ISRIsrael Arab pop 20.000112301See
DEUGermany pop 80.000139689See
CZECzech Republic NMDR0.00015099See
CHNChina Hubei Han0.00.00013732See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
ISRIsrael Georgia Jews0.00014471See
ISRIsrael Ethiopia Jews0.00015928See
ISRIsrael USA Jews0.00016058See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP Hawaiian or other Pacific Islander0.000011499See
SAUSaudi Arabia pop 6 (G)0.000028927See
USAUSA NMDP North American Amerindian0.000035791See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP Japanese0.000024582See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP Hispanic South or Central American0.0000146714See
USAUSA NMDP Mexican or Chicano0.0000261235See
USAUSA NMDP African American pop 20.0000416581See
USAUSA African American pop 40.00002411See
USAUSA Asian pop 20.00001772See
ZAFSouth Africa Natal Zulu0.00.0000100See
SGPSingapore Chinese0.00.0000149See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
DEUGermany pop 60.00018862See
CHNChina Tibet Region Tibetan0.0000158See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina North Han0.0000105See
HKGHong Kong Chinese0.00.0000569See
IDNIndonesia Java pop 20.000036See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Han Chinese0.0000504See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
PHLPhilippines Ivatan0.00.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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