Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 426 time(s) and present in 413 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MMRMyanmar Kayah89.10.654555See
MMRMyanmar Kachin82.50.634963See
INDIndia Kerala Hindu Pulaya0.531016See
MMRMyanmar Kayin75.00.477344See
MMRMyanmar Shan64.80.435254See
MMRMyanmar Bamar65.20.434846See
MMRMyanmar Rakhine68.80.427148See
CHNChina Yunnan Province Naxi0.3800118See
MMRMyanmar Chin63.60.363655See
TWNTaiwan Hakka pop 20.3610714See
TWNTaiwan Minnan and Hakka0.3580190See
TWNTaiwan Minnan pop 20.34907137See
PHLPhilippines National Capital Region0.333051See
VNMVietnam Hanoi0.330050See
TWNTaiwan Chinese immigrants from South China0.3140172See
INDIndia sub-Himalayan West Bengal Kami55.10.3101158See
CHNChina Guangdong Province51.40.3028403See
CHNChina Wuhan49.60.2930121See
MYSMalaysia Negeri Sembilan Minangkabau0.280034See
THAThailand pop 40.277016807See
THAThailand Northeast0.271066See
TWNTaiwan Chinese immigrants from Middle China0.2620211See
THAThailand Northeast pop 20.2330400See
MYSMalaysia pop 20.228062See
CHNChina Shanghai0.226026266See
MYSMalaysia Sarawak Iban0.225051See
MMRMyanmar Mon34.40.210964See
MYSMalaysia Sarawak Bidayuh0.210050See
MYSMalaysia pop 30.20901445See
INDIndia Bikaner Non-Raikas36.90.2060127See
CHNChina Shandong Province Linqu County36.70.2043139See
PAKPakistan Mixed Sindhi0.1960101See
CHNChina Shaanxi Province Han0.187010000See
CHNChina Jiangsu Province0.186020248See
TWNTaiwan Chinese immigrants from North China0.1800152See
PNGPapua New Guinea Wanigela Keapara0.176066See
MYSMalaysia Sabah Kadazan0.175057See
INDIndia North pop 30.1720587See
USAUSA OPTN Asian0.1710261See
TTOTrinidad South Asian0.170087See
ESPSpain Andalusia Romani0.169099See
CHNChina Harbin Manchu0.1620172See
ESPSpain Arratia Valley Basque0.160083See
BGDBangladesh Dhaka Bangalee0.1560141See
MYSMalaysia Perak Rawa0.150023See
INDIndia Kerala Malabar Muslim0.147034See
RUSRussia Murmansk Saomi Mixed0.140070See
CHNChina Shandong Province25.90.14007418See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.133094See
JPNJapan Aichi21.70.127050See
INDIndia North Gujarat23.70.1257338See
PAKPakistan Burusho0.125092See
KORSouth Korea pop 10.1240324See
CHNChina Yunnan Province Han pop 20.1230129See
CHNChina Harbin Korean0.1210201See
BRABrazil Parana Oriental24.20.121033See
JPNJapan pop 1122.60.120262See
MEXMexico Baja California Rural0.120050See
TWNTaiwan Aborigine0.1170111See
INDIndia Bikaner Raikas21.80.1160143See
INDIndia Kerala Syrian Christian0.113031See
FRAFrance Corsica Island0.1110100See
MNGMongolia Tarialan Khoton0.107085See
MNGMongolia Hoton0.107085See
MNGMongolia Khalkha pop 20.1060202See
INDIndia Kerala Hindu Ezhava0.104024See
KORSouth Korea pop 80.10407096See
GEOGeorgia Kurds0.103030See
AREUnited Arab Emirates pop 219.30.1020373See
IRNIran pop 40.1012855See
MNGMongolia Khalkha0.1000200See
ESPSpain Ibiza0.098088See
KURIraq Kurdistan Region18.70.0960209See
IRQIraq Erbil19.10.0956372See
JPNJapan Hyogo18.80.094032See
TURTurkey pop 50.0920142See
JPNJapan Hyogo Osaka and Nagano0.0920195See
ARMArmenia Shirak0.092076See
INDIndia Jalpaiguri Toto17.50.091740See
BRABrazil South Ribeirao Preto0.0910184See
JPNJapan Kyoto and Osaka0.0910165See
IRNIran Royan Cord Blood Bank17.30.090015600See
ESPSpain North Cabuerniga0.089095See
ROMRomania pop 316.90.08881469See
ESPSpain Majorca and Minorca0.088090See
SAUSaudi Arabia16.70.087318See
JPNJapan pop 20.0850916See
INDIndia Kerala Hindu Nair0.085041See
ARMArmenia Syunik0.0850117See
ESPSpain North Cantabria0.084083See
ARMArmenia living in Lebanon0.0820368See
ARMArmenia living in Iran0.082085See
GBRUnited Kingdom Orkney0.080088See
ITAItaly East Sicily16.00.080050See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks15.20.0800112See
GRCGreece North0.0800500See
CUBCuba Mixed0.080078See
ROMRomania pop 20.08006936See
GBRUnited Kingdom pop 20.0800101See
FRAFrance Rennes pop 30.0800200See
MEXMexico Nayarit Rural0.078164See
PRTPortugal Faro0.07701242See
ITAItaly Sardinia pop30.0770100See
MNGMongolia Oold0.0770104See
MNGMongolia Tsaatan0.0760144See
MKDMacedonia pop 30.0760172See
BRABrazil Parana Japanese14.00.0760192See
GBRUnited Kingdom North0.0756330See
GRCGreece pop 70.075311250See
PRTPortugal Beja0.0750699See
INDIndia Kerala Hindu Namboothiri0.075040See
RUSRussia Tatars0.0746355See
MEXMexico Durango, Durango city0.0742153See
RUSRussia South Ural Tatar14.80.0740135See
ESPSpain Sevilla14.80.0737278See
PRTPortugal Evora0.0730737See
PRTPortugal Portalegre0.07301254See
BRABrazil Sao Paulo Mixed14.00.0730239See
PRTPortugal Guarda0.0720797See
SVNSlovenia pop 313.90.0720130See
PRTPortugal North pop 20.07151801See
GBRUnited Kingdom Central0.0712135See
CHESwitzerland Aargau-Solothurn0.07081838See
MKDMacedonia MBMDR - Macedonian13.70.07011283See
SRBSerbia Vojvodina13.20.0700400See
PRTPortugal Bragança0.0700301See
RUSRussia Northwest pop 213.50.0700346See
PRTAzores Terceira Island0.0700130See
VENVenezuela Caracas Mestizo0.070050See
ESPSpain, Castilla y Leon, Northwest,13.60.07001743See
ALBAlbania pop 213.40.0694432See
MNGMongolia Ulaanbaatar Khalkha0.069041See
PRTPortugal Castelo Branco0.0690327See
PRTPortugal Aveiro0.06905933See
PRTPortugal Porto0.06907937See
FRAFrance Reims0.0690102See
IRLIreland South pop 20.068717624See
ENGEngland North West Mixed pop 213.70.0686379See
ARGArgentina Corrientes13.50.0680155See
PRTPortugal Center pop 20.0680562See
ARMArmenia Yerevan0.0680445See
FRAFrance Rennes pop 413.60.06791000See
ITAItaly North Pavia pop 30.0672685See
PRTPortugal Coimbra0.06705057See
ESPSpain Majorcans Jews0.0660103See
RUSRussia Moscow Pop 212.20.06542000See
CZECzech Republic Romani pop 213.00.065246See
ITAItaly pop 613.00.0652184See
SVKSlovakia pop 20.06514234See
RUSRussia Northwest pop 312.00.0650100See
PRTPortugal Setubal0.06505268See
PRTPortugal Lisbon0.065017420See
RUSRussia Samara Region0.06502500See
SCOScotland Orkney13.00.065099See
ESPSpain Minorca0.065094See
POLPoland pop 312.90.06442907See
PRTPortugal Viseu0.06402915See
VENVenezuela Colonia Tovar0.064086See
ARGArgentina Buenos Aires12.70.0640466See
ISRIsrael Moroccan Jews0.0640113See
ARMArmenia Lori0.0640102See
USAUSA OPTN Caucasian0.06308525See
RUSRussia Moscow0.06302650See
HRVCroatia pop 312.50.0625120See
PRTPortugal Viana do Castelo0.0620706See
ARMArmenia Ghegharkunik0.0620242See
ARMArmenia living in Karabakh0.0620445See
ENGEngland Leeds12.00.06195024See
DZAAlgeria pop 212.00.0619106See
CHESwitzerland Bern0.06183545See
BRABrazil Curitiba-Parana Mixed0.0615264See
SRBSerbia pop 311.90.06131992See
FRAFrance Lyon12.10.06104813See
WALWales pop 211.90.061039979See
ESPSpain Gipuzkoa Basque0.0610100See
FRAFrance Grenoble, Nantes and Rennes0.06106094See
RUSRussia Chuvash0.061082See
TURTurkey pop 20.0610228See
AUSAustralia West Caucasian11.90.0610891See
ENGEngland Liverpool11.80.06081343See
NORNorway ethnic Norwegians11.80.06064510See
CHESwitzerland Sion0.0601832See
BRABrazil Paraná Caucasian11.40.0601641See
RUSRussia Transbaikal Territory Buryats12.00.0600150See
RUSRussia Northwest11.60.05971011See
PRTPortugal South pop 20.05901021See
PRTPortugal Vila Real0.05901167See
PRTPortugal Leiria0.05901847See
ITAItaly North Pavia pop 211.30.05902416See
PRTPortugal Braga0.05801971See
PRTPortugal Santarem0.05803865See
RUSRussia South Ural Bashkir11.60.0580146See
CHESwitzerland Graubunden0.0580759See
FRAFrance Grenoble11.60.05801000See
ARGArgentina Cuyo Region11.20.0580420See
MEXMexico Jalisco Rural0.0580585See
MEXMexico Guanajuato, Leon0.057778See
MEXMexico San Luis Potosi Rural0.057587See
ENGEngland Newcastle11.10.05712739See
ENGEngland London Ashkenazi Jews0.0570500See
ARGArgentina Buenos Aires pop 211.10.05701216See
GRCGreece pop311.00.0566246See
ENGEngland Manchester11.00.05661640See
MEXMexico Chihuahua Rural0.0565236See
BRABrazil REDOME Sao Paulo0.0563800809See
ITAItaly North Pavia0.056081See
MEXMexico Mestizo pop 40.0558269See
MEXMexico Queretaro, Queretaro city0.055645See
GBRUnited Kingdom South West0.0552163See
BRABrazil Sao Paulo Bauru Mixed0.05503542See
BRABrazil REDOME Goias0.055088574See
BRABrazil Minas Gerais State Mixed10.70.05501000See
ENGEngland Sheffield10.70.05504755See
SWESweden pop 410.80.0549966See
MEXMexico Morelos, Cuernavaca0.054982See
BRABrazil REDOME Federal District0.054529549See
BRABrazil REDOME Minas Gerais0.0544211275See
MEXMexico Michoacan Rural0.0544348See
BRABrazil REDOME Parana0.0542341639See
CHESwitzerland Lausanne0.0542993See
ALBAlbanian Kosovo0.0542120See
BRABrazil REDOME Pernambuco0.054092332See
ISRIsrael Jews pop 210.40.054023000See
ARMArmenia living in USA0.0540233See
MEXMexico Jalisco, Zapopan0.0536168See
MEXMexico Zacatecas, Zacatecas city0.053684See
BRABrazil South East Cord Blood0.053611409See
BRABrazil REDOME Rondonia0.053654396See
BRABrazil REDOME Alagoas0.053325349See
MEXMexico Baja California, La Paz0.053375See
AUTAustria Cord Bloods0.05331368See
ITAItaly Lombardy10.70.0530674See
BRABrazil Rio Grande do Sul Caucasoid0.05304428See
BRABrazil REDOME Rio Grande do Sul0.0530241329See
NORNorway pop 20.0530576See
BRABrazil Parana Caucasian10.70.05302775See
BRABrazil REDOME Santa Catarina0.0528106673See
BRABrazil REDOME Mato Grosso do Sul0.052795667See
MKDMacedonia MBMDR - Macedonian Muslims10.50.052676See
MEXMexico Nuevo Leon Rural0.0523439See
GBRUnited Kingdom East0.0521163See
MEXMexico Zacatecas Rural0.0520266See
CHESwitzerland Lugano0.05201169See
BRABrazil Parana Cafuzo10.30.0520319See
ENGEngland Lancaster10.10.0518545See
CHESwitzerland St Gallen0.05162113See
MEXMexico Tamaulipas Rural0.0516125See
FRAFrance Marseille10.30.05141000See
GTMGuatemala, Guatemala City Mixed Ancestry10.20.0512127See
SWESweden Stockholm9.90.05101347See
FRAFrance Bordeaux10.20.0510990See
CHESwitzerland Zurich0.05104875See
BRABrazil REDOME Ceara0.0506101217See
BRABrazil REDOME Rio de Janeiro0.0504139322See
MEXMexico Chihuahua Chihuahua City0.0504119See
BRABrazil REDOME Mato Grosso0.050334649See
BRABrazil Rio Grande do Sul Mixed0.0500324See
BIHBosnia and Herzegovina pop 210.00.0500120See
ESPSpain Majorca0.0500407See
MEXMexico Jalisco, Tlajomulco0.050030See
MEXMexico San Luis Potosi, San Luis Potosi city0.050030See
MEXMexico Mexico City Mestizo0.0496121See
MEXMexico Jalisco, Guadalajara city0.04941189See
MEXMexico Hidalgo Rural0.049481See
BRABrazil REDOME Paraiba0.049343868See
BRABrazil REDOME Sergipe0.04907321See
CHESwitzerland Luzern0.04901553See
MKDMacedonia pop 40.0490216See
HRVCroatia pop 20.0490100See
TUNTunisia pop 30.0490104See
BRABrazil REDOME Acre0.0489859See
MEXMexico Nuevo Leon, Monterrey city0.0487226See
MEXMexico Mexico City Center0.0487152See
BRABrazil REDOME Tocantins0.048620692See
BRABrazil REDOME Rio Grande do Norte0.048546603See
BIHBosnia and Herzegovina0.0485134See
BRABrazil Rio Grande do Norte Mestizo0.048012973See
ITAItaly Bergamo8.90.0480101See
CHESwitzerland Basel0.04761888See
CHESwitzerland Geneva pop 20.04761267See
BRABrazil REDOME Roraima0.04714140See
BRABrazil REDOME Espirito Santo0.047188485See
BRABrazil Piaui Mixed0.047021943See
PRTMadeira pop 30.0470538See
IRQIraq Arabs9.40.0470149See
RUSRussia South Ural Russian8.70.0460207See
BRABrazil REDOME Bahia0.045947399See
MEXMexico Guanajuato, Guanajuato city0.045522See
MEXMexico Sonora, Ciudad Obregón0.0455143See
MEXMexico Baja Californa, Mexicali0.0450100See
ARGArgentina La Plata9.00.0450100See
SWESweden Uppsala8.70.0444300See
BRABrazil REDOME Piaui0.044246140See
NORNorway Sami0.0440200See
PERPeru Arequipa Mestizo8.80.0440168See
ESPSpain Murcia0.0440173See
DEUGermany Essen8.60.0440174See
RUSRussia North Ossetian7.10.0433127See
FRAFrance Southeast8.50.0430130See
ESPSpain Pas Valley0.043088See
BRABrazil Parana Mixed race8.60.0430186See
USAUSA OPTN Hispanic0.04301580See
BRABrazil REDOME Para0.042472637See
MEXMexico Aguascalientes state0.042195See
BRABrazil REDOME Maranhao0.041910180See
CHLChile Santiago0.0418920See
MEXMexico Tapachula, Chiapas Mestizo Population8.30.041772See
MEXMexico Nayarit, Tepic0.041297See
MEXMexico Sinaloa Rural0.0410183See
MEXMexico Sonora, Hermosillo0.040499See
BRABrazil REDOME Amazonas0.040224129See
BRABrazil REDOME Amapa0.040117864See
ESPSpain Catalonia Girona0.040088See
GRCGreece Crete0.0400135See
ISRIsrael Ashkenazi Jews pop 20.0400132See
ITAItaly Rome8.00.0400100See
ECUEcuador Coast Mixed Ancestry0.0399238See
GAZGaza Palestinians0.0390165See
BRABrazil Para State8.90.03905000See
IRNIran pop 10.039064See
MEXMexico Sinaloa, Culiacán0.0388103See
MEXMexico Jalisco, Tlaquepaque0.038539See
MEXMexico Mexico City South0.038552See
SDNSudan East Rashaida7.40.037727See
MEXMexico Mestizo7.30.037041See
MEXMexico Michoacan, Morelia0.0364150See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.036096See
MARMorocco pop 20.0360110See
MEXMexico Sinaloa Mestizo0.036056See
MEXMexico Durango Rural0.0352326See
MKDMacedonia MBMDR - Albanian6.30.0352128See
MEXMexico Coahuila, Torreon0.0350396See
PRTMadeira pop 20.0350173See
MEXMexico Queretaro Rural0.034943See
MEXMexico Colima Rural0.034143See
SAUSaudi Arabia pop 20.0340383See
CZECzech Republic Kurd6.80.033874See
MEXMexico Guanajuato Rural0.0337162See
MEXMexico Yucatan, Merida0.0333192See
MEXMexico Mexico City Metropolitan Area Rural0.0329150See
MEXMexico Colima, Colima city0.032861See
BRABrazil Para Cord Blood Unit6.20.0321841See
MARMorocco Casablanca0.0300100See
ESPSpain Andalusia0.030099See
RUSRussia Arkhangelsk Pomor0.030063See
MEXMexico Jalisco, Tonala0.028635See
MEXMexico Zacatecas, Fresnillo0.0286103See
MEXMexico Chiapas, Tuxtla Gutierrez0.028352See
MEXMexico Chihuahua, Ciudad Juarez0.0278106See
MEXMexico Coahuila Rural0.0275216See
CUBCuba Mixed pop 20.0270189See
MEXMexico Veracruz, Cordoba0.026856See
COLColombia Barranquilla0.0265188See
MEXMexico Veracruz, Veracruz city0.0262171See
MEXMexico Yucatan Rural0.0261132See
ECUEcuador Amazonia Mixed Ancestry0.025639See
ECUEcuador Mixed Ancestry0.02511173See
MEXMexico Veracruz, Orizaba0.025060See
BRABrazil Pernambuco Mixed0.0250101See
MEXMexico Tabasco Rural0.0246142See
SAUSaudi Arabia pop 44.60.0241499See
BRABrazil Rio Grande do Sul Black0.0240248See
ARGArgentina Rosario Toba4.70.023086See
ECUEcuador Andes Mixed Ancestry0.0225824See
MEXMexico Puebla, Puebla city0.02231994See
MEXMexico Veracruz, Poza Rica0.022245See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
MEXMexico Campeche Rural0.021347See
MEXMexico Guerrero state0.0208144See
MEXMexico Chiapas Rural0.0207121See
MEXMexico Puebla Rural0.0204833See
SDNSudan Khartoum0.020498See
MEXMexico Sonora Rural0.0203197See
MEXMexico Baja California, Tijuana0.020025See
MEXMexico Mexico City North0.0199751See
MEXMexico Mexico City Mestizo pop 30.0190256See
RUSRussia Sakhalin Island Nivkhi0.019053See
MEXMexico Tabasco, Villahermosa0.018382See
MEXMexico Sinaloa Capomos Mayo Yoremes0.016760See
MEXMexico Mexico City West0.015233See
GTMGuatemala Mayan0.0150132See
MEXMexico Puebla Mestizo0.015099See
BOLBolivia Quechua0.014569See
MEXMexico Oaxaca Rural0.0133485See
BRABrazil Parana Afro Brazilian2.60.013077See
TUNTunisia Ghannouch0.012082See
MEXMexico Veracruz Rural0.0120539See
USAUSA OPTN African American0.01101510See
TTOTrinidad African0.010067See
MEXMexico Quintana Roo Rural0.010050See
MEXMexico Oaxaca, Oaxaca city0.0099151See
MEXMexico Tlaxcala Rural0.0090830See
ARGArgentina Chiriguano1.90.009054See
MEXMexico Veracruz, Coatzacoalcos0.008955See
MEXMexico Tlaxcala, Tlaxcala city0.0083181See
MEXMexico Coahuila, Saltillo0.006872See
BOLBolivia La Paz Aymaras0.006087See
MEXMexico Veracruz, Xalapa0.0053187See
RUSRussia Nenet Mixed0.004055See
ZAFSouth Africa Natal Zulu0.00.0000100See
CUBCuba Mixed Race0.00.000042See
ARGArgentina Salta Wichi pop 20.00.000019See
MEXMexico Huasteca Region Teenek0.000055See
CHNChina North Han0.0000105See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
MEXMexico Mexico City East0.000079See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Morelos Rural0.000030See

See also higher resolution data of this allele

Allele  Number of Populations 
 A*11:01 284 
 A*11:01:01 75 
 A*11:02 117 
 A*11:02:01 11 
 A*11:03 91 
 A*11:04 113 
 A*11:05 52 
 A*11:06 35 
 A*11:07 18 
 A*11:08 21 
 A*11:09 30 
 A*11:10 18 
 A*11:11 18 
 A*11:12 37 
 A*11:13 14 
 A*11:14 10 
 A*11:15 12 
 A*11:19 21 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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