Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 46 time(s) and present in 46 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SAUSaudi Arabia pop 6 (G)0.052828927See
GTMGuatemala Kaqchikel NA-DHS_8 (G)10.50.052619See
POLPoland BMR9.50.048623595See
INDIndia Andhra Pradesh Telugu Speaking9.70.0484186See
INDIndia Kerala Malayalam speaking9.60.0480356See
RUSRussia Nizhny Novgorod, Russians9.30.04771510See
GRCGreece Athens8.80.04401888See
IDNIndonesia Java pop 20.042036See
CRICosta Rica Central Valley Mestizo (G)8.20.0410221See
BRABrazil Rio de Janeiro Caucasian0.0403521See
RUSRussia Belgorod region7.80.0392153See
RUSRussia Bashkortostan, Tatars7.80.0391192See
USAUSA San Francisco Caucasian0.0390220See
RUSRussian Federation Vologda Region7.60.0378119See
ESPSpain, Canary Islands, Gran canaria island7.00.0372215See
NICNicaragua Mestizo (G)7.20.0360155See
BRABrazil Barra Mansa Rio State Black0.034273See
CANCanada Ojibwa NA-DHS_4 (G)6.70.033316See
RUSRussia Bashkortostan, Bashkirs6.70.0333120See
COLColombia Inga NA-DHS_11 (G)6.70.033316See
BRABrazil Barra Mansa Rio State Caucasian0.0321405See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.30.031316See
USAUSA Italy Ancestry0.0310273See
INDIndia Karnataka Kannada Speaking5.20.0260174See
MEXMexico Mixtec NA-DHS_5 (G)5.00.025020See
BOLBolivia/Chile Aymara NA-DHS_13 (G)5.00.025020See
USAUSA Mexican American Mestizo0.0240553See
BRABrazil Rio de Janeiro Black0.022168See
CHNChina Zhejiang Han0.02161734See
BRABrazil Rio de Janeiro Parda0.0206170See
CANCanada Chipewyan NA-DHS_2 (G)4.00.020025See
ZAFSouth African Indian population4.00.020050See
ZAFSouth African Mixed ancestry4.00.020050See
VNMVietnam Kinh4.00.0198101See
ENGEngland Blood Donors of Mixed Ethnicity3.90.0193519See
HKGHong Kong Chinese HKBMDR HLA 11 loci3.70.01835266See
CRICosta Rica Guanacaste Mestizo (G)3.60.0180110See
LBYLibya Cyrenaica0.0170118See
CRICosta Rica Amerindians (G)3.20.0160125See
SAUSaudi Arabia pop 53.20.0158158See
ZAFSouth African Black2.10.0106142See
CHNChina Jingpo Minority1.90.0100105See
IDNIndonesia Sundanese and Javanese0.0080201See
CRICosta Rica African -Caribbean (G)1.00.0050102See
USAUSA Spain Ancestry0.0040279See
USAUSA Arizona Gila River Pima0.00173000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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