Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 31 time(s) and present in 31 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ZAFSouth African Black20.40.1127142See
BRABrazil Rio de Janeiro Black0.080968See
COLColombia Wayuu NA-DHS_15 (G)13.30.066715See
CRICosta Rica Guanacaste Mestizo (G)12.80.0640110See
GTMGuatemala Kaqchikel NA-DHS_8 (G)10.50.052619See
ZAFSouth African Mixed ancestry10.00.050050See
CRICosta Rica African -Caribbean (G)9.80.0490102See
SAUSaudi Arabia pop 59.50.0475158See
ESPSpain, Canary Islands, Gran canaria island8.40.0442215See
BRABrazil Rio de Janeiro Parda0.0412170See
BRABrazil Barra Mansa Rio State Black0.034273See
SAUSaudi Arabia pop 6 (G)0.032128927See
NICNicaragua Mestizo (G)6.40.0320155See
USAUSA Mexican American Mestizo0.0280553See
BRABrazil Barra Mansa Rio State Caucasian0.0272405See
COLColombia Waunana NA-DHS_20 (G)5.00.025020See
BRABrazil Rio de Janeiro Caucasian0.0230521See
CRICosta Rica Central Valley Mestizo (G)4.00.0200221See
USAUSA Spain Ancestry0.0160279See
USAUSA Italy Ancestry0.0160273See
ZAFSouth African Indian population2.00.010050See
USAUSA San Francisco Caucasian0.0070220See
GRCGreece Athens1.40.00691888See
ENGEngland Blood Donors of Mixed Ethnicity1.40.0067519See
INDIndia Kerala Malayalam speaking0.80.0040356See
LBYLibya Cyrenaica0.0040118See
INDIndia Andhra Pradesh Telugu Speaking0.50.0027186See
USAUSA Arizona Gila River Pima0.00063000See
CHNChina Zhejiang Han0.00061734See
RUSRussia Nizhny Novgorod, Russians0.10.00031510See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.00.00025266See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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