Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 80 time(s) and present in 72 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Hidalgo Mezquital Valley/ Otomi22.20.125072See
INDIndia Khandesh Region Pawra0.120050See
INDIndia Tamil Nadu Nadar0.074061See
SAUSaudi Arabia pop 6 (G)0.063228927See
INDIndia West Bhil0.060050See
USAUSA African American pop 20.0570149See
CPVCape Verde Northwestern Islands0.040062See
SAUSaudi Arabia pop 56.30.0348158See
CRICosta Rica African -Caribbean (G)6.80.0340102See
BRABrazil Belo Horizonte Caucasian5.30.032095See
ISRIsrael Arab Druze0.0300101See
ZAFSouth Africa Natal Zulu6.00.0300100See
USAUSA African American pop 30.0290564See
USAUSA Caucasian pop 30.028088See
BRABrazil Barra Mansa Rio State Caucasian0.0272405See
MARMorocco Settat Chaouya5.40.027098See
MARMorocco Atlantic Coast Chaouya0.027098See
ZAFSouth African Black4.90.0247142See
CUBCuba Mixed Race4.80.024042See
BRABrazil Rio de Janeiro Caucasian0.0230521See
GNBGuinea Bissau0.023065See
PAKPakistan Brahui0.0230104See
BRABrazil Rio de Janeiro Black0.022168See
MARMorocco Nador Metalsa pop 20.021073See
INDIndia West Coast Parsi0.020050See
ZAFSouth African Indian population4.00.020050See
RUSRussia Belgorod region3.90.0196153See
INDIndia Mumbai Maratha0.019091See
INDIndia North pop 20.019072See
GRCGreece Athens3.50.01751888See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0170146See
INDIndia Andhra Pradesh Telugu Speaking3.20.0161186See
USAUSA Italy Ancestry0.0160273See
ZAFSouth Africa Caucasians0.0150102See
CRICosta Rica Central Valley Mestizo (G)2.80.0140221See
CUBCuba Caucasian2.90.014070See
NICNicaragua Mestizo (G)2.60.0130155See
PAKPakistan Mixed Sindhi0.0130101See
USAUSA Eastern European0.0120558See
INDIndia Kerala Malayalam speaking2.20.0112356See
IRNIran Baloch0.0110100See
PAKPakistan Karachi Parsi0.011091See
USAUSA San Francisco Caucasian0.0110220See
POLPoland BMR2.10.010323595See
MEXMexico Guadalajara Mestizo pop 20.0100103See
BRABrazil Mixed0.0100108See
CPVCape Verde Southeastern Islands0.008062See
FRAFrance Southeast1.50.0080130See
USAUSA Mexican American Mestizo0.0080553See
USAUSA Alaska Yupik0.0080252See
ENGEngland Blood Donors of Mixed Ethnicity1.50.0077519See
NIRIreland Northern1.30.00701000See
MNGMongolia Buryat0.0070141See
BRABrazil Barra Mansa Rio State Black0.006873See
INDIndia Karnataka Kannada Speaking1.10.0060174See
ITAItaly Bergamo1.00.0060101See
BRABrazil Rio de Janeiro Parda0.0059170See
CHLChile Santiago Mixed1.00.005070See
CZECzech Republic0.0050106See
PAKPakistan Mixed Pathan0.0050100See
RUSRussian Federation Vologda Region0.80.0042119See
ZWEZimbabwe Harare Shona0.0040230See
USAUSA Spain Ancestry0.0020279See
CHNChina Zhejiang Han0.00061734See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.10.00035266See
USAUSA Arizona Gila River Pima0.00023000See
HKGHong Kong Chinese0.00.0000569See
CHNChina North Han0.0000105See
SGPSingapore Chinese0.00.0000149See
KORSouth Korea pop 30.0000485See
MEXMexico Mestizo0.00.000041See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Baloch0.000066See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional