Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 24 time(s) and present in 23 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA San Francisco Caucasian0.1470220See
ENGEngland Blood Donors of Mixed Ethnicity25.60.1339519See
POLPoland BMR18.40.096023595See
USAUSA Italy Ancestry0.0880273See
SAUSaudi Arabia pop 515.20.0854158See
LBYLibya Cyrenaica0.0640118See
ZAFSouth African Black11.30.0599142See
ESPSpain, Canary Islands, Gran canaria island11.20.0558215See
USAUSA Mexican American Mestizo0.0410553See
CRICosta Rica Central Valley Mestizo (G)7.20.0360221See
CRICosta Rica Guanacaste Mestizo (G)7.20.0360110See
NICNicaragua Mestizo (G)7.20.0360155See
CRICosta Rica African -Caribbean (G)6.80.0340102See
ZAFSouth African Indian population4.00.020050See
ZAFSouth African Mixed ancestry4.00.020050See
INDIndia Andhra Pradesh Telugu Speaking3.20.0188186See
INDIndia Karnataka Kannada Speaking3.40.0170174See
CRICosta Rica Amerindians (G)3.20.0160125See
USAUSA Spain Ancestry0.0140279See
INDIndia Kerala Malayalam speaking2.80.0140356See
MEXMexico Hidalgo Mezquital Valley/ Otomi2.80.013972See
IDNIndonesia Sundanese and Javanese0.0030201See
USAUSA Arizona Gila River Pima0.00063000See
IDNIndonesia Java pop 20.000036See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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