Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 37 time(s) and present in 36 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
RUSRussia Bashkortostan, Bashkirs27.50.1417120See
RUSRussia Bashkortostan, Tatars14.60.0781192See
POLPoland BMR10.70.055223595See
RUSRussia Nizhny Novgorod, Russians10.30.05301510See
CHNChina Zhejiang Han0.04701734See
RUSRussia Belgorod region7.80.0458153See
RUSRussian Federation Vologda Region7.60.0378119See
GRCGreece Athens6.90.03441888See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.30.031316See
ZAFSouth African Black4.90.0247142See
USAUSA Italy Ancestry0.0240273See
BRABrazil Rio de Janeiro Parda0.0235170See
ENGEngland Blood Donors of Mixed Ethnicity4.60.0231519See
BRABrazil Barra Mansa Rio State Black0.020573See
INDIndia Karnataka Kannada Speaking4.00.0200174See
LBYLibya Cyrenaica0.0170118See
HKGHong Kong Chinese HKBMDR HLA 11 loci3.40.01695266See
ESPSpain, Canary Islands, Gran canaria island3.30.0163215See
INDIndia Andhra Pradesh Telugu Speaking3.20.0161186See
SAUSaudi Arabia pop 6 (G)0.016028927See
USAUSA Spain Ancestry0.0160279See
BRABrazil Rio de Janeiro Black0.014968See
BRABrazil Rio de Janeiro Caucasian0.0144521See
USAUSA San Francisco Caucasian0.0140220See
NICNicaragua Mestizo (G)2.60.0130155See
USAUSA Mexican American Mestizo0.0130553See
SAUSaudi Arabia pop 51.90.0127158See
IDNIndonesia Sundanese and Javanese0.0120201See
CRICosta Rica Amerindians (G)2.40.0120125See
VNMVietnam Kinh2.00.0099101See
BRABrazil Barra Mansa Rio State Caucasian0.0099405See
CRICosta Rica Guanacaste Mestizo (G)1.80.0090110See
INDIndia Kerala Malayalam speaking1.70.0080356See
CRICosta Rica Central Valley Mestizo (G)1.00.0050221See
CRICosta Rica African -Caribbean (G)1.00.0050102See
USAUSA Arizona Gila River Pima0.00033000See
IDNIndonesia Java pop 20.000036See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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